Hedgehog IN-3
Based on 1 publication(s) in Google Scholar
Hedgehog IN-3 (compound 3) is a hedgehog pathway inhibitor (IC50 = 0.01 µM). Hedgehog IN-3 can be used in cancer research.
For research use only. We do not sell to patients.
- CAS No.: 1128191-09-2
- Formula: C18H13ClF3N5O
- Molecular Weight:407.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Hedgehog IN-3
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Biological Activity
IC50: 0.01 µM (Hedgehog pathway)[1].
Hedgehog IN-3 (compound 3; 0-10 µM; 72 h) inhibits hedgehog pathway, with an IC50 value of 0.01 µM in C3H10T1/2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:C3H10T1/2 cells
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Concentration:0-10 µM
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Incubation Time:72 h
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Result:Inhibited hedgehog pathway (IC50 = 0.01 µM).
Chemical Information
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CAS No. 1128191-09-2
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Molecular Weight 407.78
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Formula C18H13ClF3N5O
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SMILES
O=C(C1=CC=C(C(F)(F)F)N=C1C)NC2=CC=C(C(C3=NC=C(N)N=C3)=C2)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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J Mol Histol
CLDN11 deficiency upregulates FOXM1 to facilitate breast tumor progression through hedgehog signaling pathway. [Abstract]2024 Dec;55(6):1259-1270. PMID: 39438406
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Hedgehog IN-3 Related Classifications
HY-153457 Related Classifications
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