HeE1-2Tyr (Standard)
HeE1-2Tyr (Standard) is the analytical standard of HeE1-2Tyr (HY-100749). This product is intended for research and analytical applications. HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. HeE1-2Tyr significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 μM) activity in vitro.
For research use only. We do not sell to patients.
- CAS No.: 2245195-67-7
- Formula: C33H30N2O6S
- Molecular Weight:582.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 2245195-67-7
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Molecular Weight 582.67
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Formula C33H30N2O6S
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SMILES
OC(C=C1)=CC=C1C[C@@H](C(O)=O)NC(C(C=C2C3=CC=CC=C3)=C4SC5=CC=C(OC6CCCCC6)C=C5N4C2=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Delia Tarantino, et al. Targeting flavivirus RNA dependent RNA polymerase through a pyridobenzothiazole inhibitor. Antiviral Res. 2016 Oct;134:226-235. [Content Brief]
[2]. Milan Dejmek, et al. Non-Nucleotide RNA-Dependent RNA Polymerase Inhibitor That Blocks SARS-CoV-2 Replication. Viruses. 2021 Aug 11;13(8):1585. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)