HER2-IN-11
HER2-IN-11 is a psoralen derivative. HER2-IN-11 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-11 induces apoptosis.
For research use only. We do not sell to patients.
- Formula: C17H11NO6
- Molecular Weight:325.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
HER2-IN-11 (50 µM) has phototoxicity against SK-BR-3 cells with the IC50 of 2.71 µM[1].
HER2-IN-11 (1-50 µM; 48 h) changes the morphology of the SK-BR-3 cells under UVA irradiation and increases the apoptotic index[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:SK-BR-3 cells
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Concentration:1, 2.5, 5, 10, 20 and 50 µM
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Incubation Time:48 hours
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Result:Broken down cells into apoptotic bodies at higher concentrations (10, 20, and 50 µM) and cell shrinkage, plasma membrane blebbing at lower concentrations (1, 2.5, and 5 µM).
Chemical Information
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Molecular Weight 325.27
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Formula C17H11NO6
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SMILES
O=C(C1=CC=CO1)NC(C2=C(OC=C2)C(OC)=C3O4)=C3C=CC4=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HER2-IN-11 Related Classifications
HY-151118 Related Classifications
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