1. Apoptosis
  2. Apoptosis
  3. HER2-IN-11

HER2-IN-11 is a psoralen derivative. HER2-IN-11 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-11 induces apoptosis.

For research use only. We do not sell to patients.

HER2-IN-11 Chemical Structure

HER2-IN-11 Chemical Structure

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HER2-IN-11 is a psoralen derivative. HER2-IN-11 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-11 induces apoptosis[1].

In Vitro

HER2-IN-11 (50 µM) has phototoxicity against SK-BR-3 cells with the IC50 of 2.71 µM[1].
HER2-IN-11 (1-50 µM; 48 h) changes the morphology of the SK-BR-3 cells under UVA irradiation and increases the apoptotic index[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis[1]

Cell Line: SK-BR-3 cells
Concentration: 1, 2.5, 5, 10, 20 and 50 µM
Incubation Time: 48 hours
Result: Broken down cells into apoptotic bodies at higher concentrations (10, 20, and 50 µM) and cell shrinkage, plasma membrane blebbing at lower concentrations (1, 2.5, and 5 µM).
Molecular Weight







Room temperature in continental US; may vary elsewhere.


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Purity & Documentation
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HER2-IN-11 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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