2. Apoptosis
  3. Apoptosis
  4. HER2-IN-11

HER2-IN-11 is a psoralen derivative. HER2-IN-11 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-11 induces apoptosis.

For research use only. We do not sell to patients.

HER2-IN-11 Chemical Structure

HER2-IN-11 Chemical Structure

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HER2-IN-11 Related Antibodies

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Description

HER2-IN-11 is a psoralen derivative. HER2-IN-11 has anti-breast cancer activity and light-activated cytotoxicity. HER2-IN-11 induces apoptosis[1].

In Vitro

HER2-IN-11 (50 µM) has phototoxicity against SK-BR-3 cells with the IC50 of 2.71 µM[1].
HER2-IN-11 (1-50 µM; 48 h) changes the morphology of the SK-BR-3 cells under UVA irradiation and increases the apoptotic index[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

HER2-IN-11 Related Antibodies

Apoptosis Analysis[1]

Cell Line: SK-BR-3 cells
Concentration: 1, 2.5, 5, 10, 20 and 50 µM
Incubation Time: 48 hours
Result: Broken down cells into apoptotic bodies at higher concentrations (10, 20, and 50 µM) and cell shrinkage, plasma membrane blebbing at lower concentrations (1, 2.5, and 5 µM).
Molecular Weight

325.27

Formula

C17H11NO6
SMILES

O=C(C1=CC=CO1)NC(C2=C(OC=C2)C(OC)=C3O4)=C3C=CC4=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HER2-IN-11 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HER2-IN-11Apoptosispsoralen derivativeanti-breast cancerlight-activated cytotoxicitySK-BR-3 cellsInhibitorinhibitorinhibit

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HER2-IN-11
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HY-151118
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