Hydroxyevodiamine
Hydroxyevodiamine inhibits aldose reductase with an IC50 value of 24.1 μM.
For research use only. We do not sell to patients.
- CAS No.: 1238-43-3
- Formula: C19H17N3O2
- Molecular Weight:319.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | GI50 |
<0.003 μM
Compound: 10j
|
Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human A549 cells incubated for 72 hrs by MTT assay
|
[PMID: 22867019] |
| A549 | IC50 |
0.084 μM
Compound: 1b
|
Antiproliferative activity against human A549 cells incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human A549 cells incubated for 72 hrs by CCK8 assay
|
[PMID: 32292547] |
| HCT-116 | GI50 |
<0.003 μM
Compound: 10j
|
Cytotoxicity against human HCT116 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human HCT116 cells incubated for 72 hrs by MTT assay
|
[PMID: 22867019] |
| HCT-116 | IC50 |
0.055 μM
Compound: 1b
|
Antiproliferative activity against human HCT116 cells incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human HCT116 cells incubated for 72 hrs by CCK8 assay
|
[PMID: 32292547] |
| MCF7 | IC50 |
0.27 μM
Compound: 1b
|
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by CCK8 assay
Antiproliferative activity against human MCF7 cells incubated for 72 hrs by CCK8 assay
|
[PMID: 32292547] |
| MDA-MB-435 | GI50 |
<0.003 μM
Compound: 10j
|
Cytotoxicity against human MDA-MB-435 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human MDA-MB-435 cells incubated for 72 hrs by MTT assay
|
[PMID: 22867019] |
Chemical Information
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CAS No. 1238-43-3
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Molecular Weight 319.36
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Formula C19H17N3O2
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SMILES
O=C1C2=C(N(C3(C4=C(CCN13)C5=C(C=CC=C5)N4)O)C)C=CC=C2
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)