HO-PEG11-OH
Based on 1 Customer Validation
HO-PEG11-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.41%
- CAS No.: 6809-70-7
- Formula: C22H46O12
- Molecular Weight:502.59
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6809-70-7
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Appearance Solid-Liquid Mixture
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Molecular Weight 502.59
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Formula C22H46O12
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Color Colorless to off-white
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SMILES
OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (198.97 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9897 mL | 9.9485 mL | 19.8969 mL | 49.7423 mL |
| 5 mM | 0.3979 mL | 1.9897 mL | 3.9794 mL | 9.9485 mL | |
| 10 mM | 0.1990 mL | 0.9948 mL | 1.9897 mL | 4.9742 mL | |
| 15 mM | 0.1326 mL | 0.6632 mL | 1.3265 mL | 3.3162 mL | |
| 20 mM | 0.0995 mL | 0.4974 mL | 0.9948 mL | 2.4871 mL | |
| 25 mM | 0.0796 mL | 0.3979 mL | 0.7959 mL | 1.9897 mL | |
| 30 mM | 0.0663 mL | 0.3316 mL | 0.6632 mL | 1.6581 mL | |
| 40 mM | 0.0497 mL | 0.2487 mL | 0.4974 mL | 1.2436 mL | |
| 50 mM | 0.0398 mL | 0.1990 mL | 0.3979 mL | 0.9948 mL | |
| 60 mM | 0.0332 mL | 0.1658 mL | 0.3316 mL | 0.8290 mL | |
| 80 mM | 0.0249 mL | 0.1244 mL | 0.2487 mL | 0.6218 mL | |
| 100 mM | 0.0199 mL | 0.0995 mL | 0.1990 mL | 0.4974 mL |
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