HO-PEG14-OH
Based on 1 Customer Validation
HO-PEG14-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 1189112-05-7
- Formula: C28H58O15
- Molecular Weight:634.75
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1189112-05-7
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Appearance Liquid (Density: 1.116 g/cm3)
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Molecular Weight 634.75
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Formula C28H58O15
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Color Colorless to light yellow
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SMILES
OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (157.54 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5754 mL | 7.8771 mL | 15.7542 mL | 39.3856 mL |
| 5 mM | 0.3151 mL | 1.5754 mL | 3.1508 mL | 7.8771 mL | |
| 10 mM | 0.1575 mL | 0.7877 mL | 1.5754 mL | 3.9386 mL | |
| 15 mM | 0.1050 mL | 0.5251 mL | 1.0503 mL | 2.6257 mL | |
| 20 mM | 0.0788 mL | 0.3939 mL | 0.7877 mL | 1.9693 mL | |
| 25 mM | 0.0630 mL | 0.3151 mL | 0.6302 mL | 1.5754 mL | |
| 30 mM | 0.0525 mL | 0.2626 mL | 0.5251 mL | 1.3129 mL | |
| 40 mM | 0.0394 mL | 0.1969 mL | 0.3939 mL | 0.9846 mL | |
| 50 mM | 0.0315 mL | 0.1575 mL | 0.3151 mL | 0.7877 mL | |
| 60 mM | 0.0263 mL | 0.1313 mL | 0.2626 mL | 0.6564 mL | |
| 80 mM | 0.0197 mL | 0.0985 mL | 0.1969 mL | 0.4923 mL | |
| 100 mM | 0.0158 mL | 0.0788 mL | 0.1575 mL | 0.3939 mL |
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