HOTN
HOTN is a hypochlorous acid (HClO) Fluorescent indicator. HOTN is oxidized by HClO, causing cleavage of its Py+-N+ moiety and a change in hydrophobicity, which in turn triggers aggregation-induced emission to generate a strong fluorescent signal. HOTN is used for in vivo imaging of inflammation and hepatocellular carcinoma, as these diseases typically result in high levels of HClO.
For research use only. We do not sell to patients.
- CAS No.: 2677830-11-2
- Formula: C39H40Br2N2O
- Molecular Weight:712.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 2677830-11-2
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Molecular Weight 712.56
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Formula C39H40Br2N2O
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SMILES
C[N+](C)(CCC[N+]1=CC=C(C=C1)/C=C/C2=CC=C(C=C2)/C(C3=CC=CC=C3)=C(C4=CC=C(C=C4)O)\C5=CC=CC=C5)C.[Br-].[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)