2. MAPK/ERK Pathway
  3. MAP4K
  4. HPK1-IN-41

HPK1-IN-41 (compound Z389) is a HPK1 inhibitor with an IC50 value of 0.21 μM. HPK1-IN-41 can be used for the research of preventing and/or treating diseases or conditions associated with HPK1 activity.

For research use only. We do not sell to patients.

HPK1-IN-41

HPK1-IN-41 Chemical Structure

CAS No. : 2828455-23-6

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HPK1-IN-41 Related Antibodies

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MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

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Description

HPK1-IN-41 (compound Z389) is a HPK1 inhibitor with an IC50 value of 0.21 μM. HPK1-IN-41 can be used for the research of preventing and/or treating diseases or conditions associated with HPK1 activity[1].

IC50 & Target

IC50: 0.21 μM (HPK1)[1].
Molecular Weight

471.59

Formula

C28H33N5O2
CAS No.
SMILES

CC1=CNC2=C1C=C(C3=CC(CCN(C(N4CC5OC(CC5)C4)=O)C6)=C6C([C@@H]7CCCN7)=C3)C=N2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HPK1-IN-41 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HPK1-IN-412828455-23-6MAP4KMAPK Kinase Kinase KinaseHPK1cancerInhibitorinhibitorinhibit

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