HPK1-IN-48
HPK1-IN-48 (compound 14g) is a potent Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor with a IC50 of 0.15 nM. HPK1-IN-48 significantly suppresses the phosphorylation of SLP76 with a IC50 of 27.92 nM.
For research use only. We do not sell to patients.
- Formula: C33H38N8O3
- Molecular Weight:594.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All MAP4K Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 594.71
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Formula C33H38N8O3
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SMILES
COC1=C(C=CC(N2CC(N(C(C2)C)C)C)=C1)NC3=C(C=NC(NC4=CC=C(C=C4)C(NCC5=CC=CC=C5)=O)=N3)C(N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)