Hypnophilin
Hypnophilin has a variety of activities, including anti-Gram-positive bacteria, negative bacteria, yeast, mold and tumor activities.
For research use only. We do not sell to patients.
- CAS No.: 80677-96-9
- Formula: C15H20O3
- Molecular Weight:248.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| BC | IC50 |
>20 μg/mL
Compound: 7
|
Cytotoxicity against human BC cells by SRB assay
Cytotoxicity against human BC cells by SRB assay
|
[PMID: 16309322] |
| KB | IC50 |
>20 μg/mL
Compound: 7
|
Cytotoxicity against human KB cells by SRB assay
Cytotoxicity against human KB cells by SRB assay
|
[PMID: 16309322] |
| NCI-H187 | IC50 |
>20 μg/mL
Compound: 7
|
Cytotoxicity against human NCI-H187 cells by SRB assay
Cytotoxicity against human NCI-H187 cells by SRB assay
|
[PMID: 16309322] |
| Vero | IC50 |
>50 μg/mL
Compound: 7
|
Cytotoxicity against african green monkey Vero cells by SRB assay
Cytotoxicity against african green monkey Vero cells by SRB assay
|
[PMID: 16309322] |
Chemical Information
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CAS No. 80677-96-9
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Molecular Weight 248.32
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Formula C15H20O3
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SMILES
C[C@]12[C@@]3(C[C@]4([H])[C@@]2([H])[C@H](C(C)(C4)C)O)[C@](C(C1=C)=O)([H])O3
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Structure Classification
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Initial Source
Pleurotellus hypnophilus 539
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Gram Staining of Tissue Sections
Gram staining of tissue sections is a histochemical technique used to differentiate Gram-positive and Gram-negative bacteria within histological specimens based on differences in bacterial cell wall structure and dye retention, adapted from classical bacteriological Gram staining into tissue-compatible “histological Gram stain” variants. In tissue applications, modifications of the Brown-Hopps and Brown-Brenn methods are commonly used to improve differentiation of microorganisms embedded within host connective tissue and to reduce overstaining or loss of Gram-negative signal, which are known limitations of earlier approaches. The principle relies on crystal violet-iodine complex retention in Gram-positive organisms and subsequent decolorization and counterstaining steps that allow contrast visualization of Gram-negative organisms against tissue background.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)