IAA65
IAA65 is a potent T-type calcium channel inhibitor with a IC50 value of 18.9 µM. IAA65 can be used for epilepsy research.
For research use only. We do not sell to patients.
- CAS No.: 2987139-96-6
- Formula: C16H13F6NO2
- Molecular Weight:365.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Calcium Channel Isoforms
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Biological Activity
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T-type calcium channel |
IAA65 (50 µM; differentiated ND7/23 cells) causes a significant reduction in the current density generated by T-type Ca2+ channel activation[1].
IAA65 (50 µM; differentiated ND7/23 cells) alters the steady-state inactivation of Cav3.2 and Cav3.3 T-type Ca2+ channels, which resulted in a significant increase in the inactivation recovery time of the channels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2987139-96-6
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Molecular Weight 365.27
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Formula C16H13F6NO2
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SMILES
O=C(NC1=CC(CC(C)C1)=O)C2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IAA65 Related Classifications
HY-150541 Related Classifications
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