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Cat. No.: HY-106463

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Hexaprofen

Hexaprofen is a 2-arylpropionic acid derivative. Hexaprofen inhibits CXCL8-induced chemotaxis, while no activity is detected against CXCL1-induced chemotaxis.

For research use only. We do not sell to patients.

CAS No.: 24645-20-3
Formula: C₁₅H₂₀O₂
Molecular Weight:232.32

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Hexaprofen Chemical Structure

CAS No.: 24645-20-3

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Sample (0.1mg)

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

Hexaprofen is a 2-arylpropionic acid derivative. Hexaprofen inhibits CXCL8-induced chemotaxis, while no activity is detected against CXCL1-induced chemotaxis^[1].

All CXCR Isoforms :

In Vitro

Hexaprofen (compound 5) (10 nM) inhibits CXCL8-induced chemotaxis of human polymorphonuclear neutrophils (PMNs) by 10%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 24645-20-3
Molecular Weight 232.32
Formula C₁₅H₂₀O₂
SMILES

O=C(O)C(C1=CC=C(C=C1)C2CCCCC2)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Moriconi A, et al. Design of noncompetitive interleukin-8 inhibitors acting on CXCR1 and CXCR2. J Med Chem. 2007;50(17):3984-4002. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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