IDO1-IN-36
IDO1-IN-36 is a selective, mixed-type IDO1 inhibitor with an IC50 of 0.72 μM against hIDO1. IDO1-IN-36 exhibits extremely low cytotoxicity in cancer cells. IDO1-IN-36 can be used for the research of breast cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2131827-12-6
- 分子式: C14H12N4O
- 分子量:252.27
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
[1]|
hIDO1 0.72 μM (IC50) |
体外実験
IDO1-IN-36 (Compound 5a) (10 μM) inhibits purified hIDO1 enzyme, with an IC50 of 0.72 μM and an inhibition rate of 98% at a concentration of 10 μM[1].
IDO1-IN-36 inhibits IFN-γ-induced IDO1 activity in MDA-MB-231 breast cancer cells, with an EC50 of 381 nM[1].
IDO1-IN-36 exhibits 17-fold higher selectivity for purified hIDO1 over purified hTDO, with an IC50 of 12.3 μM against TDO[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2131827-12-6
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分子量 252.27
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分子式 C14H12N4O
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SMILES
O=C(C1=NNC2=C1C=CC=C2)NNC3=CC=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
IDO1-IN-36 関連分類
HY-184105 関連分類
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