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Cat. No.: HY-176245

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Illudinine

Illudinine, a sesquiterpenoid alkaloid, is a monoamine oxidase B (MAO-B) inhibitor with an IC₅₀ of 18.3 μM. Illudinine can be used for research on neurological diseases.

For research use only. We do not sell to patients.

CAS No.: 18500-63-5
Formula: C₁₆H₁₇NO₃
Molecular Weight:271.31

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Illudinine Chemical Structure

CAS No.: 18500-63-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Illudinine, a sesquiterpenoid alkaloid, is a monoamine oxidase B (MAO-B) inhibitor with an IC₅₀ of 18.3 μM. Illudinine can be used for research on neurological diseases^[1].

IC₅₀ & Target^[1]

MAO-B

18.3 μM (IC₅₀)

All Monoamine Oxidase Isoforms :

MAO-A
MAO-B

Chemical Information

CAS No. 18500-63-5
Molecular Weight 271.31
Formula C₁₆H₁₇NO₃
SMILES

O=C(C1=C(CC(C)(C2)C)C2=C(OC)C3=C1C=CN=C3)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gaston R Jr, et al. Synthesis of Illudinine from Dimedone and Identification of Activity as a Monoamine Oxidase Inhibitor. J Org Chem. 2020 Nov 6;85(21):13429-13437. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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