IMP-1575
IMP-1575 is the most potent Hedgehog acyltransferase (HHAT) inhibitor, with an IC50 of 0.75 μM for inhibition of purified HHAT. IMP-1575 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 3026255-85-3
- Formula: C19H25N3OS
- Molecular Weight:343.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293-A | CC50 |
>100 μM
Compound: 30; IMP-1575
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Cytotoxicity against human SHH+ HEK293a cells assessed as cell viability measured after 72 hrs by MTS assay
Cytotoxicity against human SHH+ HEK293a cells assessed as cell viability measured after 72 hrs by MTS assay
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[PMID: 38198226] |
Chemical Information
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CAS No. 3026255-85-3
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Molecular Weight 343.49
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Formula C19H25N3OS
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SMILES
O=C(N1CCC2=C([C@@H]1C3=NC(C)=CC=C3)C=CS2)CNCC(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
IMP-1575 Related Classifications
HY-161175 Related Classifications
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