NM107 (Standard)
NM107 (Standard) is the analytical standard of NM107. This product is intended for research and analytical applications. NM107 (2'-C-Methylcytidine) is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, the EC50 of NM107 in the wild-type replicon cells is 1.85 μM.
For research use only. We do not sell to patients.
- Purity: 98%
- CAS No.: 20724-73-6
- Formula: C10H15N3O5
- Molecular Weight:257.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 20724-73-6
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Molecular Weight 257.24
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Formula C10H15N3O5
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SMILES
OC[C@@H]1[C@@H](O)[C@](O)(C)[C@H](N2C(N=C(N)C=C2)=O)O1
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Synonyms
2'-C-Methylcytidine (Standard)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Mathy JE, et al, Combinations of cyclophilin inhibitor NIM811 with hepatitis C Virus NS3-4A Protease or NS5B polymerase inhibitors enhance antiviral activity and suppress the emergence of resistance. Antimicrob Agents Chemother. 2008 Sep;52(9):3267-75. [Content Brief]
[2]. Guedj J, et al. Modeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-life. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3991-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)