Ioxynil
Based on 1 Customer Validation
Ioxynil is an herbicide that act as endocrine disruptor. Ioxynil can disrupt vascular and heart development in zebrafish.
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- Pureté: 98.0%
- CAS No.: 1689-83-4
- Formule: C7H3I2NO
- Masse moléculaire:370.91
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Stockage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 1689-83-4
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Appearance Solid
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Masse moléculaire 370.91
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Formule C7H3I2NO
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Color White to off-white
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SMILES
N#CC1=CC(I)=C(C(I)=C1)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvant et solubilité
DMSO : 100 mg/mL (269.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureté et documentation
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Fiche technique (271 KB)
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SDS (789 KB)
- English - EN (789 KB)
- Français - FR (789 KB)
- Deutsch - DE (789 KB)
- Norwegian - NO (789 KB)
- Español - ES (789 KB)
- Swedish - SV (789 KB)
- Italian - IT (789 KB)
- Korean - KR (789 KB)
- Portuguese - PT (789 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Holtze MS, et, al. Microbial degradation of the benzonitrile herbicides dichlobenil, bromoxynil and ioxynil in soil and subsurface environments--insights into degradation pathways, persistent metabolites and involved degrader organisms. Environ Pollut. 2008 Jul;154(2):155-68. [Content Brief]
[2]. Li YF, et, al. Ioxynil and diethylstilbestrol disrupt vascular and heart development in zebrafish. Environ Int. 2019 Mar:124:511-520. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6961 mL | 13.4804 mL | 26.9607 mL | 67.4018 mL |
| 5 mM | 0.5392 mL | 2.6961 mL | 5.3921 mL | 13.4804 mL | |
| 10 mM | 0.2696 mL | 1.3480 mL | 2.6961 mL | 6.7402 mL | |
| 15 mM | 0.1797 mL | 0.8987 mL | 1.7974 mL | 4.4935 mL | |
| 20 mM | 0.1348 mL | 0.6740 mL | 1.3480 mL | 3.3701 mL | |
| 25 mM | 0.1078 mL | 0.5392 mL | 1.0784 mL | 2.6961 mL | |
| 30 mM | 0.0899 mL | 0.4493 mL | 0.8987 mL | 2.2467 mL | |
| 40 mM | 0.0674 mL | 0.3370 mL | 0.6740 mL | 1.6850 mL | |
| 50 mM | 0.0539 mL | 0.2696 mL | 0.5392 mL | 1.3480 mL | |
| 60 mM | 0.0449 mL | 0.2247 mL | 0.4493 mL | 1.1234 mL | |
| 80 mM | 0.0337 mL | 0.1685 mL | 0.3370 mL | 0.8425 mL | |
| 100 mM | 0.0270 mL | 0.1348 mL | 0.2696 mL | 0.6740 mL |
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