PGF - placental growth factor Gene

Also Known as PGFL; PIGF; PLGF; PlGF-2; D12S1900; SHGC-10760

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 5228

About PGF

Cytogenetic location: 14q24.3 Genomic coordinates (GRCh38): 14:74,941,830-74,955,764 (from NCBI)

This gene has 8 transcripts (splice variants), 224 orthologues and 4 paralogues. Biased expression in placenta (RPKM 36.3), thyroid (RPKM 24.1) and 13 other tissues.

Summary

This gene encodes a growth factor found in placenta which is homologous to vascular endothelial growth factor. Alternatively spliced transcripts encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011]

PGF Products (3)

mRNA	Protein	Name
NM_001207012.1	NP_001193941.1	placenta growth factor isoform 2 precursor
NM_001293643.1	NP_001280572.1	placenta growth factor isoform 3 precursor
NM_002632.6	NP_002623.2	placenta growth factor isoform 1 precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables growth factor activity	IMP IMP: Inferred from mutant phenotype	21215706	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	14684734	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in positive regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	21215706	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PGF Protein Structure

PDGF

0
100
200
221 a.a.

Protein Preferred Names	Protein Names
placenta growth factor	placental growth factor, vascular endothelial growth factor-related protein

Recombinant PGF Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70749	PLGF-2 Protein, Human (HEK293, His)	P49763-3 (L19-R170)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P74626	PLGF-2 Protein, Human (HEK293, mFc)	P49763-3/NP_002623.2 (L19-R170)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P74627	PLGF-1 Protein, Human	P49763-2 (L19-R149)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P74627A	PLGF-1 Protein, Human (N-His)	P49763-2 (L19-R149)	≥ 95%, as determined by reducing SDS-PAGE.

PGF Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81689	PLGF Antibody (YA1434)	FC, ELISA	Human
HY-P82067	PLGF Antibody (YA1812)	WB, ICC/IF, IHC-P	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Placental Insufficiency	Uteroplacental Vascular Insufficiency
Placenta Disease	Placenta Diseases Placenta Disorder Pregnancy Complications Placenta Disorders
Severe Pre-Eclampsia	Severe Preeclampsia Antepartum Severe Pre-Eclampsia Postpartum Severe Pre-Eclampsia Severe Pre-Eclampsia, With Delivery Severe Toxemia Severe Pre-Eclampsia, Antepartum Condition Or Complication Severe Pre-Eclampsia, Postpartum Condition Or Complication Severe Puerperal Pre-Eclampsia Severe Pre-Eclamptic Toxaemia Severe Pet - [Pre-Eclamptic Toxaemia]
Pre-Eclampsia	Preeclampsia Gestational Hypertension Hypertension Induced By Pregnancy Pre-Eclamptic Toxaemia Pregnancy Associated Hypertension Proteinuric Hypertension Of Pregnancy Hypertension, Pregnancy-Induced, Susceptibility To Preeclampsia/Eclampsia Pregnancy Toxemia Toxaemia Of Pregnancy Gestational Proteinuric Hypertension Pregnancy-Induced Hypertension Toxemia Of Pregnancy Preeclampsia, Susceptibility To Transient Hypertension Of Pregnancy Gestational [Pregnancy-Induced] Hypertension Without Significant Proteinuria Gestational Hypertension Nos Mild Proteinuric Hypertension Of Pregnancy Pih - [Pregnancy-Induced Hypertension] Pregnancy-Induced Hypertension Nos Gestational [Pregnancy-Induced] Hypertension With Significant Proteinuria Pe - [Pre-Eclampsia] Pre-Eclampsia Nos Pre-Eclamptic Nos Pregnancy Pre-Eclampsia Puerperal Pre-Eclampsia Pre-Eclampsia Toxaemia Toxaemia In Pregnancy Pet - [Pre-Eclamptic Toxaemia] Maternal Toxaemia
Placenta Accreta
Twin-To-Twin Transfusion Syndrome	Twin To Twin Transfusion Syndrome Twin Twin Transfusion Syndrome Fetal Blood Loss From Fetal Hemorrhage Into Co-Twin Fetal Hemorrhage Into Co-Twin Twin To Twin Transfusion Twin-To-Twin Blood Transfer Fetal Transfusion Syndrome Fetofetal Transfusion Syndrome Ttts Feto-Fetal Transfusion Syndrome Fetofetal Transfusion Fetus-To-Fetus Placental Transfusion Syndrome
Eclampsia	Eclampsia In Puerperium Postpartum Eclampsia Eclampsia, Postpartum Puerperal Eclampsia
Hellp Syndrome	Hemolysis, Elevated Liver Enzymes, Lowered Platelets Hemolysis, Elevated Liver Enzymes, Low Platelets In Pregnancy Hemolysis-Elevated Liver Enzymes-Low Platelets Syndrome Hellp - [Syndrome Of Haemolysis, Elevated Liver Enzymes And Low Platelet] Haemolysis-Elevated Liver Enzymes-Low Platelet Count Syndrome
Macular Degeneration, Age-Related, 1	Macular Degeneration Age-Related Macular Degeneration Macular Degeneration, Age-Related Age Related Macular Degeneration Age Related Macular Degeneration 1 ARMD1 Senile Macular Degeneration Maculopathy, Age-Related, 1 Macular Degeneration, Age-Related, Reduced Risk Of Age Related Maculopathy 1 Age Related Maculopathies Age Related Maculopathy Senile Macular Retinal Degeneration Macular Degeneration Of Retina Age-Related Maculopathy Amd Armd Age-Related Maculopathy, Susceptibility To Maculopathy Age-Related Macular Degeneration, Age-Related, 1, Susceptibility To Maculopathy, Age-Related Macular Degeneration, Age-Related, Type 1 Macular Degeneration, Age-Related, 2
Sickle Cell Disease	Hbs Disease Hemoglobin S Disease Scd Sickle Cell Disorders Sickling Disorder Due To Hemoglobin S Anemia, Sickle Cell Hb-Ss Disease Without Crisis Hbss Without Crisis Sickle-Cell Anaemia Without Crisis Scd - [Sickle Cell Disease] Sca - [Sickle Cell Anaemia] Sickle Cell Disease Nos Sickle Cell Disorder Sickle Cell Syndrome Sickle-Cell Anaemia Nos Sickle-Cell Disorder Nos Haemoglobin S Disease Haemoglobin Ss Disease Hb S Disease Hb Ss Disease Herrick Anaemia Hereditary Haemoglobinopathy Disorder Homozygous For Haemoglobin S Sickle-Cell Haemoglobin Disease Sickling Disorder Due To Haemoglobin S Hb-Ss Disease With Crisis Sickle Cell Crisis Sickle-Cell Disorder With Crisis Sickle-Cell Anaemia With Crisis Hbss With Crisis Hb S Disease With Mention Of Crisis Haemoglobin Ss Disease With Crisis Hb-Ss Disease With Vaso-Occlusive Pain Vaso-Occlusive Crisis
Gestational Diabetes	Gestational Diabetes Mellitus GDM Diabetes Mellitus Arising In Pregnancy Maternal Gestational Diabetes Mellitus Diabetes Mellitus, Gestational Diabetes Mellitus, Pregnancy Related Diabetes, Pregnancy-Induced Diabetes Gestational Diabetes, Gestational Diabetes Of Pregnancy Gdm - [Gestational Diabetes Mellitus] Gestational Diabetes Mellitus Nos Gestational Diabetes Complicating Pregnancy, Childbirth, Or The Puerperium
Kuhnt-Junius Degeneration	Neovascular Age-Related Macular Degeneration Exudative Senile Macular Degeneration Of Retina Senile Macular Degeneration, Wet Wet Senile Macular Retinal Degeneration Exudative Age-Related Macular Degeneration Exudative Macular Degeneration
Macular Retinal Edema	Macular Edema Macular Oedema Macular Retinal Oedema Macular Edema, Cystoid
Retinal Vascular Occlusion	Retinal Vasc. Occlusion Occlusion Of Retinal Vessels Retinal Obstruction
Intermittent Claudication	Charcot'S Syndrome Amyotrophic Lateral Sclerosis
Blood Group, Globoside System	Globe Disease GLOB Blood Group System, Globoside
Diabetic Macular Edema
Choriocarcinoma	Chorioepithelioma
Neovascular Glaucoma	Glaucoma, Neovascular Secondary Angle-Closure Glaucoma With Rubeosis Glaucoma Neovascular
Mild Pre-Eclampsia	Mild Toxemia
Antiphospholipid Syndrome	Antiphospholipid Antibody Syndrome Hughes Syndrome Familial Antiphospholipid Syndrome Aps Lupus Anticoagulant, Familial Anti-Phospholipid Syndrome Apls Classic Apls Classic Antiphospholipid Syndrome Acromegaloid Facial Appearance Syndrome Anticardiolipin Syndrome
Microvascular Complications Of Diabetes 5	Diabetic Retinopathy Microvascular Complications Of Diabetes, Susceptibility To, 5 MVCD5 Retinopathy, Diabetic Diabetic Nephropathy Retinopathy, Diabetic, Susceptibility To Retinal Abnormality - Diabetes-Related
Central Retinal Vein Occlusion	Crvo
Hypertension, Essential	Essential Hypertension Hypertension High Blood Pressure Hypertension, Essential, Susceptibility To Hypertensive Disease Primary Hypertension EHT Hypertension, Salt-Sensitive Essential, Susceptibility To Hyperpiesia Idiopathic Hypertension Hypertensive Disorder Hypertension, Essential, Susceptibility To, 3 Hypertension, Essential 3 Hypertension, Essential, Salt-Sensitive Hypertension, Essential, Susceptibility To, 6 Hypertension, Essential 6 Hypertension, Salt-Sensitive Essential Hypertension, Susceptibility To Hypertension, Essential, Susceptibility To, 4 Hypertension, Essential 4 Hypertension, Essential, Susceptibility To, 2 Hypertension, Essential 2 Hypertension, Essential, Susceptibility To, 1 Hypertension, Essential 1 Hypertension, Essential, Susceptibility To, 5 Hypertension, Essential 5 Htn Vascular Hypertensive Disorder Systemic Primary Arterial Hypertension Hbp - [High Blood Pressure] Systemic Arterial Hypertensive Disorder Elevated Blood Pressure Arterial Hypertension Nos Hypertension Nos Benign Hypertension Systemic Arterial Hypertension Systemic Hypertension Artery Htn Benign Htn Vascular Htn Vascular Hypertension Cholesterol Hypertension Cholesterol Htn Idiopathic Htn Malignant Hypertension Malignant Htn Raised Blood Pressure Cardiovascular Hypertension Primary Htn - [Hypertension] High Arterial Tension High Blood Pressure Disorder Ht - [Hypertension] Htn - [Hypertension] Hypertensive Vascular Disease Hypertensive Vascular Degeneration
Persistent Fetal Circulation Syndrome	Persistent Fetal Circulation Fetal Circulation Persistent Pulmonary Hypertension Of The Newborn Congenital Alveolar Capillary Dysplasia With Misalignment Of Pulmonary Veins Persistent Foetal Circulation Persistent Foetal Circulation Syndrome Pfc - [Persistent Fetal Circulation] Syndrome Pphn - [Persistent Pulmonary Hypertension Of The Newborn] Newborn Pulmonary Hypertension Primary Pulmonary Hypertension Of Newborn
Neonatal Anemia	Anemia Neonatal Anemia, Neonatal Anaemia Neonatal Neonatal Anaemia
Placental Abruption	Abruptio Placentae Abruptio Placenta Abortion, Threatened Threatened Miscarriage Haemorrhage Specified As Due To Threatened Abortion Spontaneous Threatened Abortion
Rubeosis Iridis
Ischemia	Acute Coronary Syndrome
Background Diabetic Retinopathy	Non Proliferative Diabetic Retinopathy Non-Proliferative Diabetic Retinopathy Nonproliferative Diabetic Retinopathy
Patau Syndrome	Trisomy 13 Complete Trisomy 13 Syndrome Trisomy 13 Syndrome D1 Trisomy Patau'S Syndrome Complete Trisomy 13 Chromosome 13, Trisomy 13 Complete D Trisomy Syndrome Bartholin-Patau Syndrome Chromosome 13 Duplication D1 Trisomy Syndrome D>1< Trisomy Syndrome Patau Chromosome 13 Trisomy Abnormal Autosomes 13
Down Syndrome	Trisomy 21 Complete Trisomy 21 Syndrome Down'S Syndrome Trisomy 21 Syndrome Down'S Syndrome - Trisomy 21 Downs Syndrome G Trisomy 47,Xx,+21 47,Xy,+21 Trisomy G Down Syndrome, Susceptibility To Chromosome 21 Trisomy Trisomy 21 Nos Abnormal Autosomes 21
Endophthalmitis
Severe Nonproliferative Diabetic Retinopathy	High Risk Non Proliferative Diabetic Retinopathy Severe Npdr
Degeneration Of Macula And Posterior Pole	Degeneration Of Macula And Posterior Pole Of Retina Degeneration Of Macula Or Posterior Pole Macular Degeneration Nos Degenerative Disorder Of Macula Drusen Macular Degeneration Posterior Pole Macular Degeneration Of Eye Macular Eye Degeneration Macular Degeneration Of Retina, Unspecified Pseudohole Degeneration Of Macula Of Retina
Retinal Artery Occlusion	Retina Artery Narrowing Retinal Artery Spasm Spasm Of Ophthalmic Artery Retinal Spasm Vasospasm Of Retina
Conjunctival Vascular Disease	Vascular Abnormalities Of Conjunctiva Conjunctival Vascular Abnormality Vascular Abnormality Of Conjunctiva
Exudative Vitreoretinopathy 1	Retinopathy Of Prematurity Retrolental Fibroplasia EVR1 Criswick-Schepens Syndrome Rop Exudative Vitreoretinopathy, Familial, Autosomal Dominant Fevr, Autosomal Dominant Premature Retinopathy Vitreoretinopathy, Exudative 1 Autosomal Dominant Familial Exudative Vitreoretinopathy Fevr Vitreoretinopathy, Exudative, Type 1 Retinopathy Of Prematurity Nos Rlf- [Retrolental Fibroplasia] Rop - [Retinopathy Of Prematurity] Terry Syndrome
Cerebral Angioma	Hemangioma Of Cerebrum Cerebral Hemangioma
Placenta Praevia	Placenta Previa Haemorrhage From Placenta Previa Placenta Previa Haemorrhage Lateral Placenta Low Implantation Of Placenta Nos Or With Haemorrhage Total Placenta Previa Total Placenta Praevia Nos Or With Haemorrhage Placental Previa Haemorrhage Pp - [Placenta Previa] Placenta Previa Marginalis Placenta Previa Partialis Partial Placenta Previa Placenta Previa Centralis Low Implantation Of Placenta Low Implantation Or Insertion Of Placenta Low Insertion Of Placenta Low Lying Placenta Marginal Placenta Marginal Placenta Praevia Nos Or With Haemorrhage Marginal Placenta Previa Marginal Placental Haemorrhage Partial Placenta Praevia Nos Or With Haemorrhage
Vaginal Adenoma
Vein Disease	Disorder Of Vein
Vitreous Detachment	Posterior Vitreous Detachment Vitreous Syneresis
Retinal Perforation	Retinal Break Retinal Perforations Retinal Dialysis Retinal Tear Retinal Break Nos Ruptured Retina
Angioid Streaks
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Retinal Vascular Disease	Retinal Vascular Retinal Vascular Disorder Retina Circulation Disorder
Degenerative Myopia	Pathological Myopia Myopia, Degenerative Degenerative Progressive High Myopia Progressive High Myopia Progressive High Myopia
Vaginal Benign Neoplasm
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Puerperal Pulmonary Embolism	Obstetric Pulmonary Embolism
Retinal Ischemia
Myocardial Infarction	Heart Attack Myocardial Infarction, Susceptibility To Myocardial Infarction 1 Myocardial Infarction, Protection Against Myocardial Infarction, Decreased Susceptibility To Myocardial Infarction, Decreased Myocardial Infarct MCI1 Premature Myocardial Infarction Myocardial Infarction, Susceptibility To, Type 1
Pulmonary Hypertension	Primary Pulmonary Hypertension Hypertension Pulmonary Hypertension, Pulmonary Hypertension, Pulmonary, Primary Idiopathic Pulmonary Hypertension Idiopathic Pulmonary Arterial Hypertension Pulmonary Htn - [Hypertension]
Hypertensive Encephalopathy	Encephalopathy, Hypertensive
Preterm Premature Rupture Of The Membranes	Preterm Premature Rupture Of Membranes PPROM Preterm Premature Rupture Of The Membranes, Susceptibility To Pprom - [Preterm Premature Rupture Of Membranes] Preterm Rupture Of Membranes
Oligohydramnios	Oligohydramnios - Delivered Antepartum Oligohydramnios Delivered Oligohydramnios Oligohydramnios, Antepartum Condition Or Complication Deficient Liquor Oligohydramnios, Unspecified Trimester Reduced Liquor Volume
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Peripheral Vascular Disease	Peripheral Arterial Disease Arterial Occlusive Disease Arterial Occlusive Diseases Pad Peripheral Vascular Diseases Peripheral Occlusive Disease Peripheral Arterial Diseases Helicobacter Infections
Malignant Renovascular Hypertension	Secondary Malignant Renovascular Hypertension
Orofaciodigital Syndrome Viii	Edwards Syndrome Trisomy 18 Complete Trisomy 18 Syndrome OFD8 Orofaciodigital Syndrome 8 Trisomy 18 Syndrome Oral-Facial-Digital Syndrome With Hypoplastic Epiglottis E3 Trisomy Oral-Facial-Digital Syndrome Type 8 Orofaciodigital Syndrome Type 8 Ofds Viii Oral-Facial-Digital Syndrome, Type Viii Ofd Syndrome 8 Ofds 8 Oral Facial Digital Syndrome 8 Oral Facial Digital Syndrome Type 8 18 Trisomy Chromosome 18 Trisomy Trisomy 16-18 Trisomy E Trisomy E Syndrome Chromosome 18 Duplication Oral-Facial-Digital Syndrome, Edwards Type Orofaciodigital Syndrome, Edwards Type Chromosome 18, Trisomy Cleft Lip/Palate With Abnormal Thumbs And Microcephaly Trisomy 18 Chromosome Abnormal Autosomes 18
Gestational Trophoblastic Neoplasm	Hydatidiform Mole Molar Pregnancy Gestational Trophoblastic Neoplasia Gestational Trophoblastic Tumor Gtn Gestational Trophoblastic Disease Gestational Trophoblastic Neoplasms Hydatidiform Mole, Recurrent, 1 Hydatidiform Mole Benign Trophoblastic Disease Trophoblastic Disease Nos Trophoblastic Disorder Vesicular Mole Nos Vesicular Mole Hydatidiform Mole Nos
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Familiar Ovarian Carcinoma
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Anomaly Coronary Artery Disease, Susceptibility To Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Eye Degenerative Disease
Medulloblastoma	MDB Cpnet Localized Primitive Neuroectodermal Tumor Classic Medulloblastoma Medulloblastoma Predisposition Syndrome Medulloblastoma, Somatic Brain Medulloblastoma Cns Pnet Infratentorial Primitive Neuroectodermal Tumor Neuroectodermal Tumors, Primitive Medulloblastomas Desmoplastic Medulloblastoma Medulloblastoma, With Extensive Nodularity Medulloblastoma Of Unspecified Site Medullomyoblastoma Of Unspecified Site
Vulvar Leiomyoma
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Diabetes Mellitus	Diabetes
Meningioma, Familial	Meningioma Familial Meningioma Meningioma, Familial, Susceptibility To Meningeal Neoplasm Meningeal Neoplasms Meningiomas Meningioma, Nf2-Related, Somatic Meningioma, Sis-Related Meningothelial Cell Tumor Neoplasm Of The Meninges Primary Meningeal Tumor Familial Multiple Meningioma MNGMA Meningioma, Benign, No Icd-O Subtype Intracranial Meningioma Meningothelial Cell Neoplasm Supratentorial Meningioma Primary Neoplasm Of Spinal Meninges Benign Intracranial Meningioma Benign Meningioma Meningeal Tumours Meningeal Sarcoma Of Unspecified Site Meningothelial Sarcoma Of Unspecified Site
Gastrointestinal Stromal Tumor	GIST Gastrointestinal Stromal Tumors Gastrointestinal Stromal Sarcoma Gastrointestinal Stromal Tumor, Familial Gant Gastrointestinal Stromal Tumour Stromal Tumor Of Gastrointestinal Tract Stromal Tumour Of Gastrointestinal Tract Gastrointestinal Stromal Neoplasm Paraganglioma And Gastric Stromal Sarcoma Plexosarcoma
Eye Disease	Eye Diseases Abnormality Of The Eye Toxoplasma Oculopathy
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Type 2 Diabetes Diabetes Mellitus, Non-Insulin-Dependent T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12956	Dinoprost		99.84%	Unkown
HY-12956A	Dinoprost tromethamine salt		98.0%	Unkown
HY-128428	Carboprost		99.84%	Unkown
HY-116733	Tafluprost ethyl ester	Agonist	/	Unkown
HY-124219	17-Phenoxy trinor prostaglandin F2α ethyl amide	Agonist	/	Unkown

Clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Phase
HY-101438	Darbufelone	Inhibitor	99.49%	Phase 3
HY-106037	PGF2α-isopropyl ester		/	Phase 3
HY-112284	Ebopiprant	Antagonist	98.65%	Phase 2

Pre-clinical Phase

Bioactive Molecules (136)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-113209	8-Isoprostaglandin F2α		99.9%	Unkown
HY-12956S	Dinoprost-d4		99.9%	Unkown
HY-100449	AL-8810		99.00%	Unkown
HY-107381	(+)-Cloprostenol	Agonist	98.06%	Unkown
HY-108415	Cloprostenol sodium salt	Agonist	99.84%	Unkown
HY-113209S	8-Isoprostaglandin F2α-d4		98.41%	Unkown
HY-113246	15-keto-Prostaglandin F2a		99.2%	Unkown
HY-116161A	17-Phenyl trinor PGF2α isopropyl ester		99.76%	Unkown
HY-118816	11β-Prostaglandin F2α		95.0%	Unkown
HY-121314	Cloprostenol		99.86%	Unkown
HY-113208	13,14-Dihydro-15-keto Prostaglandin F2α		99.0%	Unkown
HY-129953	9α,11β-Prostaglandin F2α		99.9%	Unkown
HY-101438A	Darbufelone mesylate	Inhibitor	99.65%	Unkown
HY-111478	Tiaprost		98.0%	Unkown
HY-114656	Dihydro-PGF1α		/	Unkown
HY-125774S	Bimatoprost acid-d4		95.25%	Unkown
HY-131632	1a,1b-Dihomo prostaglandin F2α		/	Unkown
HY-132277S	15-Keto Bimatoprost-d5		96.65%	Unkown
HY-125774	Bimatoprost acid	Agonist	99.96%	Unkown
HY-101235	ICI 185282	Antagonist	/	Unkown
HY-105953	Froxiprost		/	Unkown
HY-108415R	Cloprostenol sodium salt (Standard)	Agonist	/	Unkown
HY-111097	AF3442	Inhibitor	/	Unkown
HY-113208A	11β-13,14-Dihydro-15-keto Prostaglandin F2α		/	Unkown
HY-113208AS1	11β-13,14-Dihydro-15-keto Prostaglandin F2α-d4		/	Unkown
HY-113209R	8-Isoprostaglandin F2α (Standard)		/	Unkown
HY-113209S2	8-Isoprostaglandin F2α-13C5		/	Unkown
HY-113459S1	13,14-Dihydro-15-keto Prostaglandin F2α-d4		/	Unkown
HY-113778	15-keto-17-phenyl trinor Prostaglandin F2α		/	Unkown
HY-113887	Prostaglandin F1β	Agonist	/	Unkown
HY-113887A	11β-Prostaglandin F1β	Control	/	Unkown
HY-113887S	Prostaglandin F1β-d9		/	Unkown
HY-113909	Dinoprost (methoxyamine)		/	Unkown
HY-114660	9,11-Methane-epoxy prostaglandin F1α		/	Unkown
HY-114687	5,7-Dihydroxy-11-ketotetranorprostanoic acid		/	Unkown
HY-114850	5-trans Prostaglandin F2β		/	Unkown
HY-114850A	(5R)-Dinoprost tromethamine		/	Unkown
HY-114867	(15R)-Bimatoprost	Control	/	Unkown
HY-116051	16,16-Dimethylprostaglandin F2α		/	Unkown
HY-116051A	16,16-Dimethylprostaglandin F2β		/	Unkown
HY-116161	Bimatoprost isopropyl ester		/	Unkown
HY-116549	Prostaglandin F2α alcohol	Agonist	/	Unkown
HY-116591	8-Iso-15-keto prostaglandin F2β		/	Unkown
HY-118294	15-OH Tafluprost	Control	/	Unkown
HY-118648	Prostaglandin F2α methyl ester	Agonist	/	Unkown
HY-118652	Δ17-6-keto Prostaglandin F1α	Agonist	/	Unkown
HY-120197	17-Phenyl trinor prostaglandin F2α methyl amide	Inhibitor	/	Unkown
HY-124085	Prostaglandin F1α alcohol		/	Unkown
HY-125150	AL-3138	Antagonist	/	Unkown
HY-125396	11-Deoxyprostaglandin F2β		/	Unkown
HY-125626	8-iso-15-keto Prostaglandin F2α	Agonist	/	Unkown
HY-126762	Fenprostalene		/	Unkown
HY-129397S	2,3-Dinor-11β-prostaglandin F2α-d9		/	Unkown
HY-12956B	(5R)-Dinoprost		/	Unkown
HY-12956S1	Dinoprost-d9		/	Unkown
HY-12956S2	Dinoprost-13C5		/	Unkown
HY-129764	Prostaglandin F3α	Substrate	/	Unkown
HY-129764A	(17E)-Prostaglandin F3α	Control	/	Unkown
HY-129953A	5-trans Prostaglandin F2α		/	Unkown
HY-129953B	15(R)-Prostaglandin F2α		/	Unkown
HY-129953C	5-trans Prostaglandin F2α tromethamine		/	Unkown
HY-129953F	Prostaglandin F2α-biotin		/	Unkown
HY-129953S	9α,11β-Prostaglandin F2α-d4		/	Unkown
HY-129953S1	9α,11β-Prostaglandin F2α-d9		/	Unkown
HY-131617	Prostaglandin F2α 1,11-lactone	Control	/	Unkown
HY-131696	11-deoxy Prostaglandin F1α	Control	/	Unkown
HY-131729	16-Phenoxy tetranor Prostaglandin A2		/	Unkown
HY-132277	15-Keto Bimatoprost	Control	/	Unkown
HY-136494	Fluprostenol		/	Unkown
HY-136627	PGF2α analogue-1		/	Unkown
HY-137024	15-Keto-PGA1	Activator	/	Unkown
HY-137412	PGF2α 1,15-lactone		/	Unkown
HY-137504	20-ethyl Prostaglandin F2α		/	Unkown
HY-137544	16-Phenyl tetranor Prostaglandin F2α		/	Unkown
HY-138244	8-iso Prostaglandin F2β		/	Unkown
HY-139063	16-Phenoxy tetranor prostaglandin F2α		/	Unkown
HY-139119	Prostaglandin F2α dimethyl amide	Antagonist	/	Unkown
HY-139121	15(R)-17-Phenyl trinor Prostaglandin F2α	Agonist	/	Unkown
HY-139124	15(R)-15-Methyl Prostaglandin F2α	Agonist	/	Unkown
HY-157660	15(R)-Prostaglandin F1α		/	Unkown
HY-158571	17-Phenoxy trinor prostaglandin F2α		/	Unkown
HY-158595	15(R),19(R)-Hydroxy prostaglandin F2α		/	Unkown
HY-158937	15(R)-15-Methyl prostaglandin F2α methyl ester	Control	/	Unkown
HY-163376	17-Trifluoromethylphenyl trinor prostaglandin F2α ethyl amide		/	Unkown
HY-163784	AKR1C3-IN-14		/	Unkown
HY-165587	BM-573	Modulator	/	Unkown
HY-172574	8-iso-17-Phenyl trinor prostaglandin F2α		/	Unkown
HY-175105	17-Phenoxy trinor prostaglandin F2α isopropyl ester		/	Unkown
HY-176011	17-Phenyl trinor prostaglandin F2α glycinamide methyl ester	Agonist	/	Unkown
HY-178792	TGI-15	Antagonist	/	Unkown
HY-179367	AR-102 free acid		/	Unkown
HY-N12119	ent-Prostaglandin F2α		/	Unkown
HY-N7857	19(R)-Hydroxy-prostaglandin F2α		/	Unkown
HY-RS10381	PGF Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS11383	Ptgfr Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W399193	PGF2α 1,9-lactone	Inhibitor	/	Unkown
HY-W746888	17-Phenyl trinor prostaglandin F2α diethyl amide		/	Unkown
HY-100449A	(S)-AL-8810	Antagonist	/	Unkown
HY-105142	M-5011	Inhibitor	/	Unkown
HY-112284A	Ebopiprant hydrochloride	Antagonist	/	Unkown
HY-113209S1	8-Isoprostaglandin F2α-d9		/	Unkown
HY-114841	ONO 207		/	Unkown
HY-116008	8-iso Prostaglandin F3α		/	Unkown
HY-116502	13,14-Dihydro-15-keto prostaglandin F2α isopropyl ester		/	Unkown
HY-116679	17-trifluoromethylphenyl trinor Prostaglandin F2α		/	Unkown
HY-117717	(Rac)-SC-31391	Activator	/	Unkown
HY-118754	13,14-Dihydro-15-keto PGF1α		/	Unkown
HY-118765	Ro 23-3423		/	Unkown
HY-120752	CAY10509	Inhibitor	/	Unkown
HY-120982	(+)-15-epi Cloprostenol		/	Unkown
HY-124175	16-Phenoxy prostaglandin F2α ethyl amide		/	Unkown
HY-124209	9-keto Fluprostenol		/	Unkown
HY-133941	2,3-Dinor-6-keto-prostaglandin F1α		/	Unkown
HY-137520	16-Phenoxy tetranor Prostaglandin F2α cyclopropyl methyl amide		/	Unkown
HY-137547	20-Hydroxy-PGF2α		/	Unkown
HY-149588	17-Trifluoromethylphenyl trinor prostaglandin F2α methyl ester		/	Unkown
HY-158782	5-trans Bimatoprost acid		/	Unkown
HY-164997	15-keto Prostaglandin F1α		/	Unkown
HY-168799	3-Methoxy prostaglandin F1α		/	Unkown
HY-168800	19(R)-Hydroxy prostaglandin F1α		/	Unkown
HY-169472	11-Deoxy prostaglandin F1β		/	Unkown
HY-172571	15(R),19(R)-Hydroxy prostaglandin F1α		/	Unkown
HY-172634	8-Iso-17-phenyl trinor prostaglandin F2β		/	Unkown
HY-175062	8-iso Prostaglandin F2α ethanolamide		/	Unkown
HY-175097	AL 8810 Ethyl amide		/	Unkown
HY-176014	17-Phenyl trinor prostaglandin F2α glycinamide		/	Unkown
HY-176017	2,3-Dinor fluprostenol		/	Unkown
HY-176096	1α-Monohomo-17-phenyl trinor Prostaglandin F2α		/	Unkown
HY-176833	Prostaglandin F2α diethyl amide		/	Unkown
HY-181444	16-Phenoxy tetranor Prostaglandin F2α methyl amide	Ligand	/	Unkown
HY-23190	17-Trifluoromethylphenyl-13,14-dihydro trinor prostaglandin F1α		/	Unkown
HY-RS18329	Pgf Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24808	Pgf Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W436495	6,15-Diketo-13,14-dihydro prostaglandin F1α		/	Unkown
HY-W701877	Latanoprost tris(triethylsilyl) ether	Control	/	Unkown
HY-W746889	17-Phenyl trinor prostaglandin F2α 1,15-lactone		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PGF	MGD	MGI:105095
Felis catus	PGF	VGNC	VGNC:80879
Bos taurus	PGF	VGNC	VGNC:32787
Macaca mulatta	PGF	VGNC	VGNC:75964
Canis familiaris	PGF	VGNC	VGNC:44457
Rattus norvegicus	PGF	RGD	RGD:619850
Others	PGF	NCBI