SNCA - synuclein alpha Gene

Also Known as PD1; NACP; PARK1; PARK4

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 6622

About SNCA

Cytogenetic location: 4q22.1 Genomic coordinates (GRCh38): 4:89,724,099-89,838,304 (from NCBI)

This gene has 17 transcripts (splice variants), 189 orthologues, 2 paralogues and is associated with 7 phenotypes. Biased expression in brain (RPKM 59.2), bone marrow (RPKM 24.6) and 2 other tissues.

Summary

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit Phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016]

SNCA Products (18)

mRNA	Protein	Name
NM_001146054.2	NP_001139526.1	alpha-synuclein isoform NACP140
NM_001375285.1	NP_001362214.1	alpha-synuclein isoform NACP140
NR_164676.1
XM_047416097.1	XP_047272053.1	alpha-synuclein isoform X1
NM_001375290.1	NP_001362219.1	alpha-synuclein isoform 3
NM_007308.3	NP_009292.1	alpha-synuclein isoform NACP112
NM_001146055.2	NP_001139527.1	alpha-synuclein isoform NACP140
NM_001375286.1	NP_001362215.1	alpha-synuclein isoform NACP140
XM_011532207.2	XP_011530509.1	alpha-synuclein isoform X1
XM_011532205.3	XP_011530507.1	alpha-synuclein isoform X1
NR_164675.1
NM_001375288.1	NP_001362217.1	alpha-synuclein isoform NACP140
XM_011532203.2	XP_011530505.1	alpha-synuclein isoform X1
XM_011532204.4	XP_011530506.1	alpha-synuclein isoform X1
NM_000345.4	NP_000336.1	alpha-synuclein isoform NACP140
XM_011532206.2	XP_011530508.1	alpha-synuclein isoform X1
NM_001375287.1	NP_001362216.1	alpha-synuclein isoform NACP140
NR_164674.1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables Hsp70 protein binding	IPI IPI: Inferred from physical interaction	18975920	GOA
enables SNARE binding	IDA IDA: Inferred from direct assay	20798282	GOA
enables actin binding	IPI IPI: Inferred from physical interaction	18331289	GOA
enables alpha-tubulin binding	IPI IPI: Inferred from physical interaction	11698390	GOA
enables calcium ion binding	IDA IDA: Inferred from direct assay	11312271	GOA
enables copper ion binding	IDA IDA: Inferred from direct assay	21319811	GOA
enables cuprous ion binding	IMP IMP: Inferred from mutant phenotype	25495902	GOA
enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process	IDA IDA: Inferred from direct assay	10818098	GOA
enables dynein complex binding	IPI IPI: Inferred from physical interaction	16176937	GOA
NOT enables fatty acid binding	IDA IDA: Inferred from direct assay	16687662	GOA
enables ferrous iron binding	IDA IDA: Inferred from direct assay	11850416	GOA
enables histone binding	IDA IDA: Inferred from direct assay	16959795	GOA
enables identical protein binding	IDA IDA: Inferred from direct assay	24936070	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	15502874	GOA
enables kinesin binding	IPI IPI: Inferred from physical interaction	16176937	GOA
enables lipid binding	EXP EXP: Inferred from Experiment	11286556	GOA
enables lipid binding	IDA IDA: Inferred from direct assay	8901511	GOA
enables magnesium ion binding	IDA IDA: Inferred from direct assay	11850416	GOA
enables molecular adaptor activity	EXP EXP: Inferred from Experiment	11286556	GOA
enables oxidoreductase activity	IDA IDA: Inferred from direct assay	21320589	GOA
NOT enables phospholipase D inhibitor activity	IDA IDA: Inferred from direct assay	19146388	GOA
enables phospholipid binding	IDA IDA: Inferred from direct assay	17222866	GOA
enables phosphoprotein binding	IDA IDA: Inferred from direct assay	21127069	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	10319874	GOA
enables tau protein binding	IDA IDA: Inferred from direct assay	17408955	GOA
enables zinc ion binding	IDA IDA: Inferred from direct assay	11850416	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in SNARE complex assembly	IDA IDA: Inferred from direct assay	20798282	GOA
involved in activation of cysteine-type endopeptidase activity involved in apoptotic process	IDA IDA: Inferred from direct assay	21050448	GOA
involved in amyloid fibril formation	EXP EXP: Inferred from Experiment	8901511	GOA
NOT involved in calcium ion homeostasis	IDA IDA: Inferred from direct assay	12239163	GOA
involved in cellular response to copper ion	IDA IDA: Inferred from direct assay	21320589	GOA
involved in negative regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	10818098	GOA
involved in negative regulation of chaperone-mediated autophagy	IMP IMP: Inferred from mutant phenotype	20697033	GOA
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	IMP IMP: Inferred from mutant phenotype	10818098	GOA
involved in negative regulation of dopamine uptake involved in synaptic transmission	IDA IDA: Inferred from direct assay	12958153	GOA
involved in negative regulation of exocytosis	IMP IMP: Inferred from mutant phenotype	12239163	GOA
involved in negative regulation of microtubule polymerization	IDA IDA: Inferred from direct assay	21127069	GOA
involved in negative regulation of monooxygenase activity	IDA IDA: Inferred from direct assay	11943812	GOA
involved in negative regulation of norepinephrine uptake	IDA IDA: Inferred from direct assay	17156375	GOA
involved in negative regulation of platelet-derived growth factor receptor signaling pathway	IDA IDA: Inferred from direct assay	12239163	GOA
involved in negative regulation of serotonin uptake	IDA IDA: Inferred from direct assay	16882008	GOA
involved in negative regulation of thrombin-activated receptor signaling pathway	IDA IDA: Inferred from direct assay	12239163	GOA
involved in negative regulation of transporter activity	IDA IDA: Inferred from direct assay	16882008	GOA
involved in positive regulation of SNARE complex assembly	IDA IDA: Inferred from direct assay	20798282	GOA
involved in positive regulation of endocytosis	IDA IDA: Inferred from direct assay	18980610	GOA
involved in positive regulation of exocytosis	IMP IMP: Inferred from mutant phenotype	30404828	GOA
involved in positive regulation of glutathione peroxidase activity	IDA IDA: Inferred from direct assay	23507046	GOA
involved in positive regulation of hydrogen peroxide catabolic process	IDA IDA: Inferred from direct assay	23507046	GOA
involved in positive regulation of inflammatory response	IDA IDA: Inferred from direct assay	25533483	GOA
involved in positive regulation of inositol phosphate biosynthetic process	IDA IDA: Inferred from direct assay	15641770	GOA
involved in positive regulation of protein localization to cell periphery	IGI IGI: Inferred from genetic interaction	25533483	GOA
involved in positive regulation of protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	21127069	GOA
involved in positive regulation of receptor recycling	IDA IDA: Inferred from direct assay	18980610	GOA
involved in positive regulation of release of sequestered calcium ion into cytosol	IDA IDA: Inferred from direct assay	15641770	GOA
involved in protein destabilization	IDA IDA: Inferred from direct assay	21320589	GOA
involved in protein tetramerization	IDA IDA: Inferred from direct assay	21841800	GOA
involved in receptor internalization	IDA IDA: Inferred from direct assay	18980610	GOA
involved in regulation of norepinephrine uptake	IGI IGI: Inferred from genetic interaction	18331289	GOA
involved in regulation of phospholipase activity	IDA IDA: Inferred from direct assay	15641770	GOA
involved in regulation of presynapse assembly	IGI IGI: Inferred from genetic interaction	25533483	GOA
involved in regulation of transmembrane transporter activity	IGI IGI: Inferred from genetic interaction	18331289	GOA
involved in response to interleukin-1	IDA IDA: Inferred from direct assay	12406186	GOA
involved in response to iron(II) ion	IDA IDA: Inferred from direct assay	11850416	GOA
involved in response to lipopolysaccharide	IDA IDA: Inferred from direct assay	12406186	GOA
involved in response to magnesium ion	IDA IDA: Inferred from direct assay	11850416	GOA
involved in response to type II interferon	IDA IDA: Inferred from direct assay	19157893	GOA
involved in synaptic vesicle exocytosis	IDA IDA: Inferred from direct assay	28288128	GOA
involved in synaptic vesicle priming	IMP IMP: Inferred from mutant phenotype	30404828	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in actin cytoskeleton	IDA IDA: Inferred from direct assay	17408955	GOA
located in axon	IDA IDA: Inferred from direct assay	12958153	GOA
located in cell cortex	IDA IDA: Inferred from direct assay	19157893	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	12406186	GOA
located in cytosol	IDA IDA: Inferred from direct assay	8248242	GOA
located in extracellular region	IDA IDA: Inferred from direct assay	15863497	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	24936070	GOA
located in growth cone	IDA IDA: Inferred from direct assay	12958153	GOA
located in inclusion body	IDA IDA: Inferred from direct assay	17222866	GOA
located in membrane	IDA IDA: Inferred from direct assay	24936070	GOA
located in nucleus	IDA IDA: Inferred from direct assay	12406186	GOA
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	20039155	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	12958153	GOA
colocalizes with platelet alpha granule membrane	IDA IDA: Inferred from direct assay	12239163	GOA
part of protein-containing complex	IMP IMP: Inferred from mutant phenotype	31034892	GOA
located in supramolecular fiber	IDA IDA: Inferred from direct assay	17222866	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNCA Protein Structure

Synuclein

0
100
140 a.a.

Protein Preferred Names	Protein Names
alpha-synuclein	I+/--synuclein non A-beta component of AD amyloid synuclein alpha-140 synuclein, alpha (non A4 component of amyloid precursor)

SNCA Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	SNCA	P37840	SGSM1	Homo sapiens	Q2NKQ1-4	Validated Y2H	32814053
Intra	SNCA	P37840	SGSM1	Homo sapiens	Q2NKQ1-4	Y2H Array	32814053
Intra	SNCA	P37840	SGSM1	Homo sapiens	Q2NKQ1-4	Y2H Pooling	32814053
Intra	SNCA	P37840	ARL16	Homo sapiens	Q0P5N6	Y2H Pooling	32814053
Intra	SNCA	P37840	ARL16	Homo sapiens	Q0P5N6	Y2H Array	32814053
Intra	SNCA	P37840	ARL16	Homo sapiens	Q0P5N6	Validated Y2H	32814053
Intra	SNCA	P37840	FKBP1A	Homo sapiens	Q0VDC6	Validated Y2H	32814053
Intra	SNCA	P37840	FKBP1A	Homo sapiens	Q0VDC6	Y2H Array	32814053
Intra	SNCA	P37840	FKBP1A	Homo sapiens	Q0VDC6	Y2H Pooling	32814053
Intra	SNCA	P37840	FOXR1	Homo sapiens	Q6PIV2	Y2H Array	32814053
Intra	SNCA	P37840	FOXR1	Homo sapiens	Q6PIV2	Validated Y2H	32814053
Intra	SNCA	P37840	FOXR1	Homo sapiens	Q6PIV2	Y2H Pooling	32814053
Intra	SNCA	P37840	LHX6	Homo sapiens	Q9UPM6	Y2H Array	32814053
Intra	SNCA	P37840	LHX6	Homo sapiens	Q9UPM6	Validated Y2H	32814053
Intra	SNCA	P37840	LHX6	Homo sapiens	Q9UPM6	Y2H Pooling	32814053
Intra	SNCA	P37840	KRTAP9-2	Homo sapiens	Q9BYQ4	Y2H Pooling	32814053
Intra	SNCA	P37840	KRTAP9-2	Homo sapiens	Q9BYQ4	Validated Y2H	32814053
Intra	SNCA	P37840	KRTAP9-2	Homo sapiens	Q9BYQ4	Y2H Array	32814053
Intra	SNCA	P37840	TBR1	Homo sapiens	Q16650	Validated Y2H	32814053
Intra	SNCA	P37840	TBR1	Homo sapiens	Q16650	Y2H Array	32814053
Intra	SNCA	P37840	TBR1	Homo sapiens	Q16650	Y2H Pooling	32814053
Intra	SNCA	P37840	SEPTIN4	Homo sapiens	O43236	Y2H Array	32814053
Intra	SNCA	P37840	SEPTIN4	Homo sapiens	O43236	Y2H Pooling	32814053
Intra	SNCA	P37840	SEPTIN4	Homo sapiens	O43236	Validated Y2H	32814053
Intra	SNCA	P37840	ATG10	Homo sapiens	Q9H0Y0	Y2H Array	32814053
Intra	SNCA	P37840	ATG10	Homo sapiens	Q9H0Y0	Y2H Pooling	32814053
Intra	SNCA	P37840	ATG10	Homo sapiens	Q9H0Y0	Validated Y2H	32814053
Intra	SNCA	P37840	CLPP	Homo sapiens	Q16740	Y2H Pooling	32814053
Intra	SNCA	P37840	CLPP	Homo sapiens	Q16740	Validated Y2H	32814053
Intra	SNCA	P37840	CLPP	Homo sapiens	Q16740	Y2H Array	32814053
Intra	SNCA	P37840	CHMP1A	Homo sapiens	Q9HD42	Validated Y2H	32814053
Intra	SNCA	P37840	CHMP1A	Homo sapiens	Q9HD42	Y2H Pooling	32814053
Intra	SNCA	P37840	CHMP1A	Homo sapiens	Q9HD42	Y2H Array	32814053
Intra	SNCA	P37840	OTUB1	Homo sapiens	Q96FW1	Validated Y2H	32814053
Intra	SNCA	P37840	OTUB1	Homo sapiens	Q96FW1	Y2H Pooling	32814053
Intra	SNCA	P37840	OTUB1	Homo sapiens	Q96FW1	Y2H Array	32814053
Intra	SNCA	P37840	MAGEC3	Homo sapiens	Q8TD91-2	Validated Y2H	32814053
Intra	SNCA	P37840	MAGEC3	Homo sapiens	Q8TD91-2	Y2H Pooling	32814053
Intra	SNCA	P37840	MAGEC3	Homo sapiens	Q8TD91-2	Y2H Array	32814053
Intra	SNCA	P37840	ARFGAP1	Homo sapiens	Q8N6T3-3	Validated Y2H	32814053
Intra	SNCA	P37840	ARFGAP1	Homo sapiens	Q8N6T3-3	Y2H Array	32814053
Intra	SNCA	P37840	ARFGAP1	Homo sapiens	Q8N6T3-3	Y2H Pooling	32814053
Intra	SNCA	P37840	C6orf141	Homo sapiens	Q5SZD1	Y2H Pooling	32814053
Intra	SNCA	P37840	C6orf141	Homo sapiens	Q5SZD1	Validated Y2H	32814053
Intra	SNCA	P37840	C6orf141	Homo sapiens	Q5SZD1	Y2H Array	32814053
Intra	SNCA	P37840	MTF2	Homo sapiens	Q9Y483-4	Validated Y2H	32814053
Intra	SNCA	P37840	MTF2	Homo sapiens	Q9Y483-4	Y2H Pooling	32814053
Intra	SNCA	P37840	MTF2	Homo sapiens	Q9Y483-4	Y2H Array	32814053
Intra	SNCA	P37840	ZNF557	Homo sapiens	Q8N988-2	Validated Y2H	32814053
Intra	SNCA	P37840	ZNF557	Homo sapiens	Q8N988-2	Y2H Array	32814053
Intra	SNCA	P37840	ZNF557	Homo sapiens	Q8N988-2	Y2H Pooling	32814053
Intra	SNCA	P37840	BAG6	Homo sapiens	P46379-2	Validated Y2H	32814053
Intra	SNCA	P37840	BAG6	Homo sapiens	P46379-2	Y2H Pooling	32814053
Intra	SNCA	P37840	BAG6	Homo sapiens	P46379-2	Y2H Array	32814053
Intra	SNCA	P37840	CLU	Homo sapiens	P10909	Anti Bait CoIP	31270237
Intra	SNCA	P37840	CLU	Homo sapiens	P10909	Anti Bait CoIP	28887769
Intra	SNCA	P37840	LDHAL6B	Homo sapiens	Q9BYZ2	Y2H Array	32814053
Intra	SNCA	P37840	LDHAL6B	Homo sapiens	Q9BYZ2	Validated Y2H	32814053
Intra	SNCA	P37840	LDHAL6B	Homo sapiens	Q9BYZ2	Y2H Pooling	32814053
Intra	SNCA	P37840	VPS29	Homo sapiens	Q9UBQ0-2	Y2H Array	32814053
Intra	SNCA	P37840	VPS29	Homo sapiens	Q9UBQ0-2	Validated Y2H	32814053
Intra	SNCA	P37840	VPS29	Homo sapiens	Q9UBQ0-2	Y2H Pooling	32814053
Intra	SNCA	P37840	AP2B1	Homo sapiens	P63010-2	Y2H Pooling	32814053
Intra	SNCA	P37840	AP2B1	Homo sapiens	P63010-2	Validated Y2H	32814053
Intra	SNCA	P37840	AP2B1	Homo sapiens	P63010-2	Y2H Array	32814053
Intra	SNCA	P37840	UBXN1	Homo sapiens	Q04323-2	Validated Y2H	32814053
Intra	SNCA	P37840	UBXN1	Homo sapiens	Q04323-2	Y2H Pooling	32814053
Intra	SNCA	P37840	UBXN1	Homo sapiens	Q04323-2	Y2H Array	32814053
Intra	SNCA	P37840	SPAG8	Homo sapiens	Q99932-2	Validated Y2H	32814053
Intra	SNCA	P37840	SPAG8	Homo sapiens	Q99932-2	Y2H Pooling	32814053
Intra	SNCA	P37840	SPAG8	Homo sapiens	Q99932-2	Y2H Array	32814053
Intra	SNCA	P37840	L3MBTL3	Homo sapiens	Q96JM7-2	Validated Y2H	32814053
Intra	SNCA	P37840	L3MBTL3	Homo sapiens	Q96JM7-2	Y2H Array	32814053
Intra	SNCA	P37840	L3MBTL3	Homo sapiens	Q96JM7-2	Y2H Pooling	32814053
Intra	SNCA	P37840	ZSCAN1	Homo sapiens	Q8NBB4-2	Y2H Array	32814053
Intra	SNCA	P37840	ZSCAN1	Homo sapiens	Q8NBB4-2	Y2H Pooling	32814053
Intra	SNCA	P37840	ZSCAN1	Homo sapiens	Q8NBB4-2	Validated Y2H	32814053
Intra	SNCA	P37840	CENPV	Homo sapiens	Q7Z7K6	Validated Y2H	32814053
Intra	SNCA	P37840	CENPV	Homo sapiens	Q7Z7K6	Y2H Array	32814053
Intra	SNCA	P37840	CENPV	Homo sapiens	Q7Z7K6	Lumier	32814053
Intra	SNCA	P37840	CENPV	Homo sapiens	Q7Z7K6	Y2H Pooling	32814053
Intra	SNCA	P37840	VHL	Homo sapiens	P40337-2	Y2H Array	32814053
Intra	SNCA	P37840	VHL	Homo sapiens	P40337-2	Y2H Pooling	32814053
Intra	SNCA	P37840	VHL	Homo sapiens	P40337-2	Validated Y2H	32814053
Intra	SNCA	P37840	APOE	Homo sapiens	P02649	Aggregation	26921451
Intra	SNCA	P37840	APOE	Homo sapiens	P02649	GMS	31270237
Intra	SNCA	P37840	APOE	Homo sapiens	P02649	ELISA	31270237
Intra	SNCA	P37840	APOE	Homo sapiens	P02649	TEM	31270237
Intra	SNCA	P37840	APOE	Homo sapiens	P02649	Anti Bait CoIP	31270237
Intra	SNCA	P37840	APOE	Homo sapiens	P02649	Anti Bait CoIP	28887769
Intra	SNCA	P37840	APOE	Homo sapiens	P02649	Solid Phase Assay	26921451
Intra	SNCA	P37840	IFI35	Homo sapiens	P80217-2	Validated Y2H	32814053
Intra	SNCA	P37840	IFI35	Homo sapiens	P80217-2	Y2H Pooling	32814053
Intra	SNCA	P37840	IFI35	Homo sapiens	P80217-2	Y2H Array	32814053
Intra	SNCA	P37840	PLEKHG7	Homo sapiens	Q6ZR37	Y2H Pooling	32814053
Intra	SNCA	P37840	PLEKHG7	Homo sapiens	Q6ZR37	Validated Y2H	32814053
Intra	SNCA	P37840	PLEKHG7	Homo sapiens	Q6ZR37	Y2H Array	32814053
Intra	SNCA	P37840	RABGEF1	Homo sapiens	Q9UJ41-4	Validated Y2H	32814053
Intra	SNCA	P37840	RABGEF1	Homo sapiens	Q9UJ41-4	Y2H Array	32814053
Intra	SNCA	P37840	RABGEF1	Homo sapiens	Q9UJ41-4	Y2H Pooling	32814053
Intra	SNCA	P37840	PARP11	Homo sapiens	Q9NR21-5	Y2H Pooling	32814053
Intra	SNCA	P37840	PARP11	Homo sapiens	Q9NR21-5	Validated Y2H	32814053
Intra	SNCA	P37840	PARP11	Homo sapiens	Q9NR21-5	Y2H Array	32814053
Intra	SNCA	P37840	UIMC1	Homo sapiens	Q96RL1-2	Validated Y2H	32814053
Intra	SNCA	P37840	UIMC1	Homo sapiens	Q96RL1-2	Y2H Array	32814053
Intra	SNCA	P37840	UIMC1	Homo sapiens	Q96RL1-2	Y2H Pooling	32814053
Intra	SNCA	P37840	TWIST2	Homo sapiens	Q8WVJ9	Y2H Pooling	32814053
Intra	SNCA	P37840	TWIST2	Homo sapiens	Q8WVJ9	Validated Y2H	32814053
Intra	SNCA	P37840	TWIST2	Homo sapiens	Q8WVJ9	Y2H Array	32814053
Intra	SNCA	P37840	PRKN	Homo sapiens	O60260-5	Y2H Array	32814053
Intra	SNCA	P37840	SERF1A	Homo sapiens	O75920-2	FPS	22854022
Intra	SNCA	P37840	RNF111	Homo sapiens	Q6ZNA4-2	Y2H Pooling	32814053
Intra	SNCA	P37840	RNF111	Homo sapiens	Q6ZNA4-2	Validated Y2H	32814053
Intra	SNCA	P37840	RNF111	Homo sapiens	Q6ZNA4-2	Y2H Array	32814053
Intra	SNCA	P37840	SYMPK	Homo sapiens	Q92797-2	Validated Y2H	32814053
Intra	SNCA	P37840	SYMPK	Homo sapiens	Q92797-2	Y2H Array	32814053
Intra	SNCA	P37840	SYMPK	Homo sapiens	Q92797-2	Y2H Pooling	32814053
Intra	SNCA	P37840	IQSEC1	Homo sapiens	Q6DN90-2	Y2H Pooling	32814053
Intra	SNCA	P37840	IQSEC1	Homo sapiens	Q6DN90-2	Validated Y2H	32814053
Intra	SNCA	P37840	IQSEC1	Homo sapiens	Q6DN90-2	Y2H Array	32814053
Intra	SNCA	P37840	ABHD17C	Homo sapiens	Q6PCB6	Validated Y2H	32814053
Intra	SNCA	P37840	ABHD17C	Homo sapiens	Q6PCB6	Y2H Pooling	32814053
Intra	SNCA	P37840	ABHD17C	Homo sapiens	Q6PCB6	Y2H Array	32814053
Intra	SNCA	P37840	RAPSN	Homo sapiens	Q13702-2	Y2H Pooling	32814053
Intra	SNCA	P37840	RAPSN	Homo sapiens	Q13702-2	Validated Y2H	32814053
Intra	SNCA	P37840	RAPSN	Homo sapiens	Q13702-2	Y2H Array	32814053
Intra	SNCA	P37840	LNX2	Homo sapiens	Q8N448	Y2H Pooling	32814053
Intra	SNCA	P37840	LNX2	Homo sapiens	Q8N448	Validated Y2H	32814053
Intra	SNCA	P37840	LNX2	Homo sapiens	Q8N448	Y2H Array	32814053
Intra	SNCA	P37840	KLK6	Homo sapiens	Q92876	Validated Y2H	32814053
Intra	SNCA	P37840	KLK6	Homo sapiens	Q92876	Y2H Array	32814053
Intra	SNCA	P37840	KLK6	Homo sapiens	Q92876	Y2H Pooling	32814053
Intra	SNCA	P37840	MPND	Homo sapiens	Q8N594	Validated Y2H	32814053
Intra	SNCA	P37840	MPND	Homo sapiens	Q8N594	Y2H Pooling	32814053
Intra	SNCA	P37840	MPND	Homo sapiens	Q8N594	Y2H Array	32814053
Cross	SNCA	P37840	N	SARS-CoV-2	P0DTC9	MST	34860005
Intra	SNCA	P37840	PACS1	Homo sapiens	Q6VY07	Validated Y2H	32814053
Intra	SNCA	P37840	PACS1	Homo sapiens	Q6VY07	Y2H Array	32814053
Intra	SNCA	P37840	PACS1	Homo sapiens	Q6VY07	Y2H Pooling	32814053
Intra	SNCA	P37840	RNF112	Homo sapiens	Q9ULX5	Validated Y2H	32814053
Intra	SNCA	P37840	RNF112	Homo sapiens	Q9ULX5	Y2H Pooling	32814053
Intra	SNCA	P37840	RNF112	Homo sapiens	Q9ULX5	Y2H Array	32814053
Intra	SNCA	P37840	OTUD7B	Homo sapiens	Q6GQQ9-2	Y2H Array	32814053
Intra	SNCA	P37840	OTUD7B	Homo sapiens	Q6GQQ9-2	Validated Y2H	32814053
Intra	SNCA	P37840	OTUD7B	Homo sapiens	Q6GQQ9-2	Y2H Pooling	32814053
Intra	SNCA	P37840	SULT4A1	Homo sapiens	Q9BR01-2	Validated Y2H	32814053
Intra	SNCA	P37840	SULT4A1	Homo sapiens	Q9BR01-2	Y2H Array	32814053
Intra	SNCA	P37840	SULT4A1	Homo sapiens	Q9BR01-2	Y2H Pooling	32814053
Intra	SNCA	P37840	LHX5	Homo sapiens	Q9H2C1	Y2H Array	32814053
Intra	SNCA	P37840	LHX5	Homo sapiens	Q9H2C1	Y2H Pooling	32814053
Intra	SNCA	P37840	LHX5	Homo sapiens	Q9H2C1	Validated Y2H	32814053
Intra	SNCA	P37840	TERF2	Homo sapiens	Q15554-4	Validated Y2H	32814053
Intra	SNCA	P37840	TERF2	Homo sapiens	Q15554-4	Y2H Array	32814053
Intra	SNCA	P37840	TERF2	Homo sapiens	Q15554-4	Y2H Pooling	32814053
Intra	SNCA	P37840	ANKRD13D	Homo sapiens	Q6ZTN6-2	Validated Y2H	32814053
Intra	SNCA	P37840	ANKRD13D	Homo sapiens	Q6ZTN6-2	Y2H Array	32814053
Intra	SNCA	P37840	ANKRD13D	Homo sapiens	Q6ZTN6-2	Y2H Pooling	32814053
Intra	SNCA	P37840	DKFZp547K2416	Homo sapiens	Q8NDP9	Y2H Array	32814053
Intra	SNCA	P37840	DKFZp547K2416	Homo sapiens	Q8NDP9	Y2H Pooling	32814053
Intra	SNCA	P37840	DKFZp547K2416	Homo sapiens	Q8NDP9	Validated Y2H	32814053
Intra	SNCA	P37840	HNRNPLL	Homo sapiens	Q8WVV9-3	Validated Y2H	32814053
Intra	SNCA	P37840	HNRNPLL	Homo sapiens	Q8WVV9-3	Y2H Array	32814053
Intra	SNCA	P37840	HNRNPLL	Homo sapiens	Q8WVV9-3	Y2H Pooling	32814053
Intra	SNCA	P37840	CAMKK1	Homo sapiens	Q8N5S9-2	Validated Y2H	32814053
Intra	SNCA	P37840	CAMKK1	Homo sapiens	Q8N5S9-2	Y2H Pooling	32814053
Intra	SNCA	P37840	CAMKK1	Homo sapiens	Q8N5S9-2	Y2H Array	32814053
Intra	SNCA	P37840	OOSP2	Homo sapiens	Q86WS3	Validated Y2H	32814053
Intra	SNCA	P37840	OOSP2	Homo sapiens	Q86WS3	Y2H Pooling	32814053
Intra	SNCA	P37840	OOSP2	Homo sapiens	Q86WS3	Y2H Array	32814053
Intra	SNCA	P37840	HES4	Homo sapiens	Q9HCC6	Y2H Pooling	32814053
Intra	SNCA	P37840	HES4	Homo sapiens	Q9HCC6	Validated Y2H	32814053
Intra	SNCA	P37840	HES4	Homo sapiens	Q9HCC6	Y2H Array	32814053
Intra	SNCA	P37840	ZMAT2	Homo sapiens	Q96NC0	Validated Y2H	32814053
Intra	SNCA	P37840	ZMAT2	Homo sapiens	Q96NC0	Y2H Array	32814053
Intra	SNCA	P37840	ZMAT2	Homo sapiens	Q96NC0	Y2H Pooling	32814053
Intra	SNCA	P37840	KLF15	Homo sapiens	Q9UIH9	Y2H Pooling	32814053
Intra	SNCA	P37840	KLF15	Homo sapiens	Q9UIH9	Validated Y2H	32814053
Intra	SNCA	P37840	KLF15	Homo sapiens	Q9UIH9	Y2H Array	32814053
Intra	SNCA	P37840	ZNF366	Homo sapiens	Q8N895	Validated Y2H	32814053
Intra	SNCA	P37840	ZNF366	Homo sapiens	Q8N895	Y2H Array	32814053
Intra	SNCA	P37840	ZNF366	Homo sapiens	Q8N895	Y2H Pooling	32814053
Intra	SNCA	P37840	BRK1	Homo sapiens	Q8WUW1	Validated Y2H	32814053
Intra	SNCA	P37840	BRK1	Homo sapiens	Q8WUW1	Y2H Pooling	32814053
Intra	SNCA	P37840	BRK1	Homo sapiens	Q8WUW1	Y2H Array	32814053
Intra	SNCA	P37840	RAN	Homo sapiens	P62826	Validated Y2H	32814053
Intra	SNCA	P37840	RAN	Homo sapiens	P62826	Y2H Array	32814053
Intra	SNCA	P37840	RAN	Homo sapiens	P62826	Y2H Pooling	32814053
Intra	SNCA	P37840	CRLF3	Homo sapiens	Q8IUI8	Validated Y2H	32814053
Intra	SNCA	P37840	CRLF3	Homo sapiens	Q8IUI8	Y2H Array	32814053
Intra	SNCA	P37840	CRLF3	Homo sapiens	Q8IUI8	Y2H Pooling	32814053
Intra	SNCA	P37840	ARFGAP3	Homo sapiens	Q9NP61	Y2H Array	32814053
Intra	SNCA	P37840	ARFGAP3	Homo sapiens	Q9NP61	Validated Y2H	32814053
Intra	SNCA	P37840	ARFGAP3	Homo sapiens	Q9NP61	Y2H Pooling	32814053
Intra	SNCA	P37840	HDAC10	Homo sapiens	Q969S8	Validated Y2H	32814053
Intra	SNCA	P37840	HDAC10	Homo sapiens	Q969S8	Y2H Pooling	32814053
Intra	SNCA	P37840	HDAC10	Homo sapiens	Q969S8	Y2H Array	32814053
Intra	SNCA	P37840	YWHAH	Homo sapiens	Q04917	Y2H Array	32814053
Intra	SNCA	P37840	YWHAH	Homo sapiens	Q04917	Validated Y2H	32814053
Intra	SNCA	P37840	YWHAH	Homo sapiens	Q04917	Y2H Pooling	32814053
Intra	SNCA	P37840	SQSTM1	Homo sapiens	Q13501	Y2H Array	32814053
Intra	SNCA	P37840	SQSTM1	Homo sapiens	Q13501	Validated Y2H	32814053
Intra	SNCA	P37840	SQSTM1	Homo sapiens	Q13501	Y2H Pooling	32814053
Intra	SNCA	P37840	TDG	Homo sapiens	Q13569	Validated Y2H	32814053
Intra	SNCA	P37840	TDG	Homo sapiens	Q13569	Y2H Array	32814053
Intra	SNCA	P37840	TDG	Homo sapiens	Q13569	Y2H Pooling	32814053
Intra	SNCA	P37840	COPS3	Homo sapiens	Q9UNS2	Y2H Array	32814053
Intra	SNCA	P37840	COPS3	Homo sapiens	Q9UNS2	Y2H Pooling	32814053
Intra	SNCA	P37840	COPS3	Homo sapiens	Q9UNS2	Validated Y2H	32814053
Intra	SNCA	P37840	GNB2	Homo sapiens	P62879	Y2H Pooling	32814053
Intra	SNCA	P37840	GNB2	Homo sapiens	P62879	Validated Y2H	32814053
Intra	SNCA	P37840	GNB2	Homo sapiens	P62879	Y2H Array	32814053
Intra	SNCA	P37840	UBA52	Homo sapiens	P62987	Y2H Array	32814053
Intra	SNCA	P37840	UBA52	Homo sapiens	P62987	Validated Y2H	32814053
Intra	SNCA	P37840	UBA52	Homo sapiens	P62987	Y2H Pooling	32814053
Intra	SNCA	P37840	PSMC1	Homo sapiens	P62191	Validated Y2H	32814053
Intra	SNCA	P37840	PSMC1	Homo sapiens	P62191	Y2H Array	32814053
Intra	SNCA	P37840	PSMC1	Homo sapiens	P62191	Y2H Pooling	32814053
Intra	SNCA	P37840	SKIC8	Homo sapiens	Q9GZS3	Y2H Array	32814053
Intra	SNCA	P37840	SKIC8	Homo sapiens	Q9GZS3	Y2H Pooling	32814053
Intra	SNCA	P37840	SKIC8	Homo sapiens	Q9GZS3	Validated Y2H	32814053
Intra	SNCA	P37840	MAPT	Homo sapiens	P10636-8	Pull Down	21985244
Intra	SNCA	P37840	INA	Homo sapiens	Q16352	Y2H Pooling	32814053
Intra	SNCA	P37840	INA	Homo sapiens	Q16352	Validated Y2H	32814053
Intra	SNCA	P37840	INA	Homo sapiens	Q16352	Y2H Array	32814053
Intra	SNCA	P37840	GSK3B	Homo sapiens	P49841	Pull Down	21985244
Intra	SNCA	P37840	TPPP	Homo sapiens	O94811	BiFC	27671864
Intra	SNCA	P37840	TPPP	Homo sapiens	O94811	Imaging	17027006
Intra	SNCA	P37840	MT-CO3	Homo sapiens	P00414	Y2H	12059041
Intra	SNCA	P37840	FEZ2	Homo sapiens	Q9UHY8	Validated Y2H	32814053
Intra	SNCA	P37840	FEZ2	Homo sapiens	Q9UHY8	Y2H Pooling	32814053
Intra	SNCA	P37840	FEZ2	Homo sapiens	Q9UHY8	Y2H Array	32814053
Intra	SNCA	P37840	MGARP	Homo sapiens	Q8TDB4	Y2H Array	32814053
Intra	SNCA	P37840	MGARP	Homo sapiens	Q8TDB4	Y2H Pooling	32814053
Intra	SNCA	P37840	MGARP	Homo sapiens	Q8TDB4	Validated Y2H	32814053
Intra	SNCA	P37840	CYCS	Homo sapiens	P99999	Validated Y2H	32814053
Intra	SNCA	P37840	CYCS	Homo sapiens	P99999	Y2H Array	32814053
Intra	SNCA	P37840	CYCS	Homo sapiens	P99999	Y2H Pooling	32814053
Intra	SNCA	P37840	HTT	Homo sapiens	P42858	BiFC	22119730
Intra	SNCA	P37840	HTT	Homo sapiens	P42858	IF	22119730
Intra	SNCA	P37840	TUBA1B	Homo sapiens	P68363	Validated Y2H	32814053
Intra	SNCA	P37840	TUBA1B	Homo sapiens	P68363	Y2H Array	32814053
Intra	SNCA	P37840	TUBA1B	Homo sapiens	P68363	Y2H Pooling	32814053
Intra	SNCA	P37840	BAX	Homo sapiens	Q07812	Validated Y2H	32814053
Intra	SNCA	P37840	BAX	Homo sapiens	Q07812	Y2H Pooling	32814053
Intra	SNCA	P37840	BAX	Homo sapiens	Q07812	Y2H Array	32814053
Intra	SNCA	P37840	VAMP2	Homo sapiens	P63027	Anti Bait CoIP	20798282
Intra	SNCA	P37840	ABL1	Homo sapiens	P00519-1	Protein Kinase Assay	24412932
Intra	SNCA	P37840	ABL1	Homo sapiens	P00519-1	NMR	24412932
Intra	SNCA	P37840	LRRK2	Homo sapiens	Q5S007	Confocal	23183827
Intra	SNCA	P37840	HSPA1A	Homo sapiens	P08107	Fluorescence	19875982
Intra	SNCA	P37840	HSPA1A	Homo sapiens	P08107	Pull Down	21985244
Intra	SNCA	P37840	HSPA1A	Homo sapiens	P08107	Comig Non-Denat Gel	19875982
Intra	SNCA	P37840	HSPA1A	Homo sapiens	P08107	NMR	19875982
Intra	SNCA	P37840	HSPA1A	Homo sapiens	P08107	FRET	19875982
Intra	SNCA	P37840	PCMTD2	Homo sapiens	Q9NV79	Validated Y2H	32814053
Intra	SNCA	P37840	PCMTD2	Homo sapiens	Q9NV79	Y2H Array	32814053
Intra	SNCA	P37840	PCMTD2	Homo sapiens	Q9NV79	Y2H Pooling	32814053
Intra	SNCA	P37840	SLC6A3	Homo sapiens	Q01959	Anti Bait CoIP	22163275
Intra	SNCA	P37840	APOA1	Homo sapiens	P02647	Anti Bait CoIP	31270237
Intra	SNCA	P37840	APOA1	Homo sapiens	P02647	Anti Bait CoIP	28887769
Intra	SNCA	P37840	PRKCE	Homo sapiens	Q02156	Validated Y2H	32814053
Intra	SNCA	P37840	PRKCE	Homo sapiens	Q02156	Y2H Array	32814053
Intra	SNCA	P37840	PRKCE	Homo sapiens	Q02156	Y2H Pooling	32814053
Intra	SNCA	P37840	SPATA22	Homo sapiens	Q8NHS9	Validated Y2H	32814053
Intra	SNCA	P37840	SPATA22	Homo sapiens	Q8NHS9	Y2H Array	32814053
Intra	SNCA	P37840	SPATA22	Homo sapiens	Q8NHS9	Y2H Pooling	32814053
Intra	SNCA	P37840	ASB13	Homo sapiens	Q8WXK3	Y2H Pooling	32814053
Intra	SNCA	P37840	ASB13	Homo sapiens	Q8WXK3	Validated Y2H	32814053
Intra	SNCA	P37840	ASB13	Homo sapiens	Q8WXK3	Y2H Array	32814053
Intra	SNCA	P37840	RABAC1	Homo sapiens	Q9UI14	Pull Down	21798244
Intra	SNCA	P37840	RABAC1	Homo sapiens	Q9UI14	IF	21798244
Intra	SNCA	P37840	STX1A	Homo sapiens	Q16623	Anti Bait CoIP	20798282
Intra	SNCA	P37840	RNF10	Homo sapiens	Q8N5U6	Y2H Pooling	32814053
Intra	SNCA	P37840	RNF10	Homo sapiens	Q8N5U6	Validated Y2H	32814053
Intra	SNCA	P37840	RNF10	Homo sapiens	Q8N5U6	Y2H Array	32814053
Intra	SNCA	P37840	KLHL20	Homo sapiens	Q9Y2M5	Y2H Pooling	32814053
Intra	SNCA	P37840	KLHL20	Homo sapiens	Q9Y2M5	Validated Y2H	32814053
Intra	SNCA	P37840	KLHL20	Homo sapiens	Q9Y2M5	Y2H Array	32814053
Intra	SNCA	P37840	PDZK1IP1	Homo sapiens	Q13113	Validated Y2H	32814053
Intra	SNCA	P37840	PDZK1IP1	Homo sapiens	Q13113	Y2H Pooling	32814053
Intra	SNCA	P37840	PDZK1IP1	Homo sapiens	Q13113	Y2H Array	32814053
Intra	SNCA	P37840	SNCAIP	Homo sapiens	Q9Y6H5	Crosslink	19762560
Intra	SNCA	P37840	SNCAIP	Homo sapiens	Q9Y6H5	Y2H	10319874
Intra	SNCA	P37840	SNCAIP	Homo sapiens	Q9Y6H5	Anti Tag CoIP	10319874
Intra	SNCA	P37840	SNCAIP	Homo sapiens	Q9Y6H5	FCS	19762560
Intra	SNCA	P37840	SNCAIP	Homo sapiens	Q9Y6H5	Pull Down	10319874
Intra	SNCA	P37840	SNCAIP	Homo sapiens	Q9Y6H5	NMR	19762560
Intra	SNCA	P37840	SNCAIP	Homo sapiens	Q9Y6H5	Pull Down	19762560
Intra	SNCA	P37840	CASP6	Homo sapiens	P55212	Y2H Pooling	32814053
Intra	SNCA	P37840	CASP6	Homo sapiens	P55212	Validated Y2H	32814053
Intra	SNCA	P37840	CASP6	Homo sapiens	P55212	Y2H Array	32814053
Intra	SNCA	P37840	SNCB	Homo sapiens	Q16143	Y2H Pooling	32814053
Intra	SNCA	P37840	SNCB	Homo sapiens	Q16143	Validated Y2H	32814053
Intra	SNCA	P37840	SNCB	Homo sapiens	Q16143	Y2H Array	32814053
Intra	SNCA	P37840	LNX1	Homo sapiens	Q8TBB1	Validated Y2H	32814053
Intra	SNCA	P37840	LNX1	Homo sapiens	Q8TBB1	Y2H Array	32814053
Intra	SNCA	P37840	LNX1	Homo sapiens	Q8TBB1	Y2H Pooling	32814053
Intra	SNCA	P37840	RBM11	Homo sapiens	P57052	Y2H Pooling	32814053
Intra	SNCA	P37840	RBM11	Homo sapiens	P57052	Validated Y2H	32814053
Intra	SNCA	P37840	RBM11	Homo sapiens	P57052	Y2H Array	32814053
Intra	SNCA	P37840	RNF183	Homo sapiens	Q96D59	Validated Y2H	32814053
Intra	SNCA	P37840	RNF183	Homo sapiens	Q96D59	Y2H Pooling	32814053
Intra	SNCA	P37840	RNF183	Homo sapiens	Q96D59	Y2H Array	32814053
Intra	SNCA	P37840	TOLLIP	Homo sapiens	Q9H0E2	Y2H Pooling	32814053
Intra	SNCA	P37840	TOLLIP	Homo sapiens	Q9H0E2	Validated Y2H	32814053
Intra	SNCA	P37840	TOLLIP	Homo sapiens	Q9H0E2	Y2H Array	32814053
Intra	SNCA	P37840	RNF138	Homo sapiens	Q8WVD3	Y2H Array	32814053
Intra	SNCA	P37840	RNF138	Homo sapiens	Q8WVD3	Validated Y2H	32814053
Intra	SNCA	P37840	RNF138	Homo sapiens	Q8WVD3	Y2H Pooling	32814053
Intra	SNCA	P37840	UBAC1	Homo sapiens	Q9BSL1	Validated Y2H	32814053
Intra	SNCA	P37840	UBAC1	Homo sapiens	Q9BSL1	Y2H Array	32814053
Intra	SNCA	P37840	UBAC1	Homo sapiens	Q9BSL1	Y2H Pooling	32814053
Intra	SNCA	P37840	H3C13	Homo sapiens	Q71DI3	Y2H Pooling	32814053
Intra	SNCA	P37840	H3C13	Homo sapiens	Q71DI3	Validated Y2H	32814053
Intra	SNCA	P37840	H3C13	Homo sapiens	Q71DI3	Y2H Array	32814053
Intra	SNCA	P37840	RYBP	Homo sapiens	Q8N488	Validated Y2H	32814053
Intra	SNCA	P37840	RYBP	Homo sapiens	Q8N488	Y2H Pooling	32814053
Intra	SNCA	P37840	RYBP	Homo sapiens	Q8N488	Y2H Array	32814053
Intra	SNCA	P37840	BCL2L1	Homo sapiens	Q07817	Y2H Array	32814053
Intra	SNCA	P37840	BCL2L1	Homo sapiens	Q07817	Y2H Pooling	32814053
Intra	SNCA	P37840	BCL2L1	Homo sapiens	Q07817	Validated Y2H	32814053
Cross	SNCA	P37840	Slc6a3	Mus musculus	Q61327	IF	22163275
Cross	SNCA	P37840	Slc6a3	Mus musculus	Q61327	Anti Bait CoIP	22163275
Intra	SNCA	P37840	H3C1	Homo sapiens	P68431	Y2H Pooling	32814053
Intra	SNCA	P37840	H3C1	Homo sapiens	P68431	Validated Y2H	32814053
Intra	SNCA	P37840	H3C1	Homo sapiens	P68431	Y2H Array	32814053
Intra	SNCA	P37840	SPPL2B	Homo sapiens	Q8TCT7-2	Validated Y2H	32814053
Intra	SNCA	P37840	SPPL2B	Homo sapiens	Q8TCT7-2	Y2H Array	32814053
Intra	SNCA	P37840	SPPL2B	Homo sapiens	Q8TCT7-2	Y2H Pooling	32814053
Intra	SNCA	P37840	METTL27	Homo sapiens	Q8N6F8	Validated Y2H	32814053
Intra	SNCA	P37840	METTL27	Homo sapiens	Q8N6F8	Y2H Array	32814053
Intra	SNCA	P37840	METTL27	Homo sapiens	Q8N6F8	Y2H Pooling	32814053
Intra	SNCA	P37840	ZNF57	Homo sapiens	Q68EA5	Y2H Array	32814053
Intra	SNCA	P37840	ZNF57	Homo sapiens	Q68EA5	Validated Y2H	32814053
Intra	SNCA	P37840	ZNF57	Homo sapiens	Q68EA5	Y2H Pooling	32814053
Intra	SNCA	P37840	ZNF296	Homo sapiens	Q8WUU4	Y2H Pooling	32814053
Intra	SNCA	P37840	ZNF296	Homo sapiens	Q8WUU4	Validated Y2H	32814053
Intra	SNCA	P37840	ZNF296	Homo sapiens	Q8WUU4	Y2H Array	32814053
Intra	SNCA	P37840	CSNK1D	Homo sapiens	P48730-2	Y2H Array	32814053
Intra	SNCA	P37840	CSNK1D	Homo sapiens	P48730-2	Y2H Pooling	32814053
Intra	SNCA	P37840	CSNK1D	Homo sapiens	P48730-2	Validated Y2H	32814053
Intra	SNCA	P37840	MSRB2	Homo sapiens	Q9Y3D2	Y2H Array	32814053
Intra	SNCA	P37840	MSRB2	Homo sapiens	Q9Y3D2	Y2H Pooling	32814053
Intra	SNCA	P37840	MSRB2	Homo sapiens	Q9Y3D2	Validated Y2H	32814053
Intra	SNCA	P37840	RNF168	Homo sapiens	Q8IYW5	Validated Y2H	32814053
Intra	SNCA	P37840	RNF168	Homo sapiens	Q8IYW5	Y2H Array	32814053
Intra	SNCA	P37840	RNF168	Homo sapiens	Q8IYW5	Y2H Pooling	32814053
Intra	SNCA	P37840	ENKUR	Homo sapiens	Q8TC29	Validated Y2H	32814053
Intra	SNCA	P37840	ENKUR	Homo sapiens	Q8TC29	Y2H Array	32814053
Intra	SNCA	P37840	ENKUR	Homo sapiens	Q8TC29	Y2H Pooling	32814053
Intra	SNCA	P37840	ABL1	Homo sapiens	P00519-2	Anti Bait CoIP	24412932
Intra	SNCA	P37840	ABL1	Homo sapiens	P00519-2	Confocal	24412932
Intra	SNCA	P37840	SMURF1	Homo sapiens	Q9HCE7-2	Validated Y2H	32814053
Intra	SNCA	P37840	SMURF1	Homo sapiens	Q9HCE7-2	Y2H Array	32814053
Intra	SNCA	P37840	SMURF1	Homo sapiens	Q9HCE7-2	Y2H Pooling	32814053
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Biophysical	21443877
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Biophysical	16330551
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	BiFC	22119730
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Fluorescence	19745811
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	GMS	19875982
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Comig Non-Denat Gel	22119730
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Cosedimentation	16764865
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	DLS	19745811
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	AFM	19745811
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	GMS	16330551
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	3D-EM	16330551
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	EM	19745811
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Pull Down	18614564
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Comigration in SDS	15502874
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	SLC	21358815
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Comig Non-Denat Gel	16330551
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Biophysical	19745811
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	NMR	19745811
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Fluorescence Spectr	16330551
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	TEM	16330551
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Aggregation	22854022
Intra	SNCA	P37840	SNCA	Homo sapiens	P37840	Filter Binding	22854022
Intra	SNCA	P37840	SOD1	Homo sapiens	P00441	SLC	26643113
Intra	SNCA	P37840	SOD1	Homo sapiens	P00441	Crosslink	26643113

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant SNCA Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70577	SNCA Protein, Human	P37840-1 (M1-A140)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P71327	SNCA Protein, Human (His)	P37840-1 (M1-A140)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P78805	SNCA Protein, Human (Biotinylated, HEK293, His-Avi)	P37840-1 (M1-A140)	≥ 95%, as determined by reducing SDS-PAGE.

SNCA Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P81739	Phospho-alpha Synuclein (Ser129) Antibody (YA1484)	WB, ICC/IF	Human, Mouse, Rat
HY-P82328	alpha Synuclein Antibody (YA2073)	WB, IHC-P, IP	Human, Rat
HY-P82328A	alpha Synuclein Antibody (YA2073)(PBS only)	WB, IHC-P, IP	Human, Rat
HY-P85380	alpha Synuclein Antibody (YA5072)	IHC-P; IHC-F; IF-Tissue	Human
HY-P86127	alpha Synuclein Antibody (YA5819)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
HY-P86701	alpha Synuclein Antibody (YA6393)	WB	Rat, Mouse, Human
HY-P86749	alpha Synuclein Antibody (YA6441)	WB, IHC-P, IHC-F, IF-Tissue	Human
HY-P86749A	alpha Synuclein Antibody (YA6441)(PBS only)	WB, IHC-P, IHC-F, IF-Tissue	Human

Related Diseases

Diseases	Alias
Tremor	Medicament-Induced Tremor Medication-Induced Postural Tremor
Subjective Cognitive Decline
Olivopontocerebellar Atrophy	Thomas Syndrome Olivopontocerebellar Atrophies Dejerine-Thomas Syndrome Thomas' Syndrome Wadia-Swami Syndrome Opca Potter Sequence-Cleft Lip/Palate-Cardiopathy Syndrome Spinocerebellar Ataxia Type 2
Toxic Encephalopathy	Neurotoxicity Neurotoxicity Syndromes Neurotoxicity Syndrome Encephalopathy, Toxic
Juvenile-Onset Parkinson'S Disease	Juvenile-Onset Parkinson Disease
Mild Cognitive Impairment
Multiple System Atrophy 1	Multiple System Atrophy Shy-Drager Syndrome Msa MSA1 Multiple System Atrophy 1, Susceptibility To Sporadic Olivopontocerebellar Atrophy Multisystem Atrophy Msa1, Susceptibility To Multiple System Atrophy, Susceptibility To Opca Progressive Autonomic Failure With Multiple System Atrophy Sds
Autosomal Dominant Cerebellar Ataxia	Spinocerebellar Ataxia Adca Pierre Marie Cerebellar Ataxia Ataxia, Spinocerebellar Sca Autosomal Dominant Spinocerebellar Ataxia Spinocerebellar Ataxias
Early-Onset Parkinson'S Disease	Early-Onset Parkinson Disease
Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1	FTDALS1 Frontotemporal Dementia And/Or Motor Neuron Disease Ftdmnd Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia Alsftd Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis-1 Frontotemporal Dementia With Motor Neuron Disease Ftdals Ftd-Als Ftd-Mnd Frontotemporal Dementia With Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis With Frontotemporal Dementia 1 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Dementia, Frontotemporal, And/Or Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis And/Or Frontotemporal Dementia 1 Frontotemporal Lobar Degeneration Grn-Related Frontotemporal Dementia
Arteriolosclerosis
Parkinson Disease, Late-Onset	Parkinson Disease Parkinson'S Disease PD PARK Parkinson Disease, Susceptibility To Late Onset Parkinson'S Disease Late Onset Parkinson Disease Paralysis Agitans Primary Parkinsonism Idiopathic Parkinson Disease Parkinson'S Parkinson Disease, Late-Onset, Susceptibility To Parkinson Disease, Age Of Onset, Modifier Lewy Body Parkinson Disease Idiopathic Parkinson'S Disease Pd - [Parkinson Disease] Parkinson Disease Nos Parkinson, Nos Primary Parkinson Disease
Speech And Communication Disorders	Language Disorder Communication Disorder Language Disorders Communication Disorders Speech Language Disorder Speech-Language Disorder Communication Impairment Speech And Language Disorder
Coenzyme Q10 Deficiency, Primary, 1	COQ10D1 Ubiquinone Deficiency 1 Coenzyme Q Deficiency 1 Coq Deficiency 1 Coq10 Deficiency, Primary, 1 Primary Coenzyme Q10 Deficiency 1 Primary Coq10 Deficiency 1 Coenzyme Q10 Deficiency, Primary, Type 1
Kuru	Kuru, Susceptibility To Kuru Encephalopathy Kuru Encephalitis Kuru Disease
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Disease Of Mental Health	Mental Health Mental Disorders
Supranuclear Palsy, Progressive, 1	Progressive Supranuclear Palsy Steele-Richardson-Olszewski Syndrome Supranuclear Palsy, Progressive Psp Progressive Supranuclear Ophthalmoplegia PSNP1 Familial Progressive Supranuclear Palsy Richardson'S Syndrome Psp Syndrome Progressive Supranuclear Palsy 1 Supranuclear Palsy Progressive Ophthalmoplegia, Supranuclear, Progressive Steele-Richardson-Olszewksi Syndrome
Amyotrophic Lateral Sclerosis 1	Amyotrophic Lateral Sclerosis ALS Lou Gehrig Disease Amyotrophic Lateral Sclerosis Type 1 Charcot Disease ALS1 Amyotrophic Lateral Sclerosis, Susceptibility To Fals Lou Gehrig'S Disease Mnd Motor Neuron Disease Familial Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis 1, Familial Amyotrophic Lateral Sclerosis 1, Autosomal Dominant Motor Neuron Disease, Bulbar Motor Neurone Disease Amyotrophic Lateral Sclerosis With Dementia Dementia With Amyotrophic Lateral Sclerosis Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic Sclerosis, Lateral, Amyotrophic, Type 1 Amyotrophic Sclerosis Als - [Amyotrophic Lateral Sclerosis] Wasting Palsy Amyotrophic Paralysis Amyotrophy Lateral Sclerosis Wasting Paralysis Spinal Progressive Amyotrophy Progressive Atrophic Paralysis
Niemann-Pick Disease	Sphingomyelin/Cholesterol Lipidosis Niemann-Pick Diseases Lipoid Histiocytosis Sphingomyelin Lipidosis Sphingomyelinase Deficiency Disease Lipid Histiocytosis Neuronal Cholesterol Lipidosis Neuronal Lipidosis Npd Sphingomyelinase Deficiency Niemann-Pick Disease, Type A
Retinitis Pigmentosa	RP Rod-Cone Dystrophy Autosomal Recessive Retinitis Pigmentosa Non-Syndromic Retinitis Pigmentosa Pericentral Pigmentary Retinopathy Pigmentary Retinopathy Tapetoretinal Degeneration Rcd Retinitis Pigmentosa Autosomal Recessive ARRP Retinitis Pigmentosa, Autosomal Recessive Retinitis Pigmentosa 1
Choreatic Disease	Chorea Hereditary Chorea
Cerebral Degeneration	Brain Degeneration Degenerative Brain Disorder
Alzheimer Disease 7	Ad7 Alzheimer'S Disease 7 Alzheimer Disease, Familial, 7 Alzheimer Disease-7 Alzheimer Disease, Familial 7
Dementia	Dementias Presenile Dementia Alzheimer Type Dementia Alzheimer Sclerosis Alzheimer Disease Dementia Alzheimer Dementia Primary Degenerative Alzheimer Type Dementia End Stage Alzheimer'S Dementia Alzheimer'S Type Atypical Dementia Alzheimer Type Presenile Dementia Early Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 2 Dementia In Alzheimer Disease With Early Onset Early Onset Alzheimer Type Dementia, Uncomplicated Primary Degenerative Alzheimer Type Dementia, Early Onset Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated Alzheimer Disease Dementia With Early Onset Presenile Sclerosis Presenile Brain Sclerosis Presenile Alzheimer Brain Sclerosis Late Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 1 Dementia In Alzheimer Disease With Late Onset Primary Degenerative Alzheimer Type Dementia, Late Onset Sdat - [Senile Dementia, Alzheimer Type] Alzheimer Disease Dementia With Late Onset Late Onset Alzheimer Brain Sclerosis Senile Alzheimer Brain Disease Senile Alzheimer Brain Sclerosis Senile Primary Degenerative Alzheimer Type Dementia Senile Dementia Of The Alzheimer Type Arteriosclerotic Dementia Strategic-Infarct Dementia Post Stroke Dementia Vascular Cognitive Impairment Vascular Dementia Dementia Of The Lewy Body Type Dementia With Lewy Bodies Sdlt - [Senile Dementia Of The Lewy Body Type] Senile Dementia Of The Lewy Body Type Alcohol-Related Dementia Alcoholic Dementia Nos Alcohol-Induced Dementia Alcoholic Brain Syndrome Chronic Alcoholic Brain Syndrome Alcohol Dementia Late Onset Alcoholic Psychosis Residual And Late-Onset Alcohol-Induced Psychotic Disorder Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder Late-Onset Psychoactive Substance-Induced Psychotic Disorder Inhalant Dementia Volatile Solvents Dementia Dementia In Paralysis Agitans Pdd - [Parkinson Disease Dementia] Dementia Syndrome Of Parkinson Disease Dementia In Parkinson Disease Parkinson Related Dementia Dementia In Huntington Chorea Hiv - [Human Immunodeficiency Virus] Dementia Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex Aids Related Dementia Dementia Due To Niacin Deficiency
Muscular Atrophy	Muscle Wasting Amyotrophia Wasting - Muscle Skeletal Muscle Atrophy
Ideomotor Apraxia	Apraxia, Ideomotor Classic Apraxia Ideomotor Dyspraxia Limb-Kinetic Apraxia Transcortical Apraxia
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Neuronal Ceroid Lipofuscinosis	Hereditary Ceroid Lipofuscinosis Batten Disease Ncl Neuronal Ceroid-Lipofuscinoses Lipofuscinosis, Ceroid, Neuronal Juvenile Neuronal Ceroid Lipofuscinosis Cerebromacular Dystrophy Cerebromacular Degeneration Ceroid-Lipofuscinosis Ncl - [Neuronal Ceroid Lipofuscinosis] Amaurotic Familial Idiocy Amaurotic Idiocy Amaurotic Idiot Neuronal Lipofuscinosis Pigmentary Retinal Lipoid Neuronal Heredodegeneration
Anxiety	Anxiety Disorder Anxiety Disorders Anxiety State Anxieties Anxiety Neurosis
Tay-Sachs Disease	Hexosaminidase A Deficiency TSD Hexa Deficiency Gm2 Gangliosidosis, Type 1 Hexosaminidase Alpha-Subunit Deficiency Gm2-Gangliosidosis, Several Forms Gm2-Gangliosidosis, B, B1, Ab Variant B Variant Gm2 Gangliosidosis Sphingolipidosis, Tay-Sachs Gm2-Gangliosidosis, Type I B Variant Gm2-Gangliosidosis Hex A Pseudodeficiency Hexa Disorders Beta-Hexosaminidase A Deficiency Gm2 Gangliosidosis, Type I Gangliosidosis Gm2 , Type 1 Gm2 Gangliosidosis, B, B1 Variant Gm2-Gangliosidosis 1 GM2G1 Gm2-Gangliosidosis B Variant Tay-Sachs Disease Pseudo-Ab Variant Tay-Sachs Disease Variant B1 Gangliosidoses, Gm2
Hereditary Ataxia	Sca Spinocerebellar Ataxia Ataxias Hereditary Ataxias, Hereditary
Amyloidosis, Hereditary, Transthyretin-Related	Transthyretin Amyloidosis Familial Amyloid Polyneuropathy Ttr Amyloid Neuropathy Transthyretin Amyloid Neuropathy Transthyretin Amyloid Polyneuropathy Fap Familial Transthyretin Amyloidosis Amyloidosis Transthyretin Related Type I Familial Amyloid Polyneuropathy Familial Amyloid Polyneuropathy Type I Attrv122i Amyloidosis Hereditary Amyloidosis, Transthyretin-Related Amyloid Polyneuropathy, Familial Attr Amyloidosis Attrm Amyloidosis Corino De Andrade'S Disease Paramyloidosis Transthyretin-Related Hereditary Amyloidosis Ttr Amyloidosis Hereditary Attr Amyloidosis Portuguese Polyneuritic Amyloidosis Portuguese Type Familial Amyloid Neuropathy Swiss Type Amyloid Polyneuropathy Type Ii Familial Amyloid Polyneuropathy Attrv30m Amyloidosis Attrv30m-Related Amyloidosis Familial Amyloid Polyneuropathy, Portuguese-Swedish-Japanese Type Attr Cardiomyopathy Attrv122i-Related Amyloidosis Ttr-Related Amyloid Cardiomyopathy Ttr-Related Cardiac Amyloidosis Transthyretin Amyloid Cardiopathy Transthyretin-Related Familial Amyloid Cardiomyopathy Amyloidosis, Transthyretin-Related AMYL-TTR Amyloidosis I Amyloidosis Ohio Type Amyloidosis Type 7 Amyloidosis Vii Amyloid Polyneuropathy Attr Familial Amyloid Polyneuropathy Type Ii Hereditary Amyloidosis Transthyretin-Related Leptomeningeal Amyloidosis Meningocerebrovascular Amyloidosis Oculoleptomeningeal Amyloidosis Familial Amyloid Polyneuropathies Amyloidosis, Leptomeningeal Senile Cardiac Amyloidosis Amyloid Neuropathies, Familial Danish Type Familial Amyloid Cardiomyopathy Familial Amyloid Neuropathy, Portuguese Type Amyloid Polyneuropathy, Swiss Type Hereditary Oculoleptomeningeal Amyloid Angiopathy Amyloid Neuropathies
Aspiration Pneumonia	Pneumonia, Aspiration Pneumonia Aspiration Aspiration Pneumonitis
Sleep Disorder	Sleep Disorders Non-Organic Sleep Disorder
Meier-Gorlin Syndrome 3	MGORS3 Meier-Gorlin Syndrome, Type 3
Neuroaxonal Dystrophy	Neuroaxonal Dystrophies
Amyloidosis, Familial Visceral	Ostertag Type Amyloidosis German Type Amyloidosis Amyloidosis Viii Amyloidosis, 3 Or More Types Familial Visceral Amyloidosis Familial Amyloid Nephropathy Familial Renal Amyloidosis Hereditary Amyloid Nephropathy Amyloidosis, Familial Renal Amyloidosis, Systemic Nonneuropathic Amyloidosis Familial Visceral Amyloidosis 8 Amyloidosis, Ostertag Type Hereditary Amyloidosis With Primary Renal Involvement Hereditary Renal Amyloidosis Renal Amyloidosis Amyloidosis, Renal Systemic Nonneuropathic Amyloidosis Amyloidosis Familial Renal Amyloidosis Systemic Nonneuropathic Hereditary Amyloidosis With Primary Renal Involement AMYL8 Systemic Non-Neuropathic Amyloidosis Amyloid Nephropathy
Sphingolipidosis	Sphingolipidoses
Parkinson Disease 3, Autosomal Dominant	Parkinson Disease 3 PARK3 Parkinson Disease 3, Autosomal Dominant Lewy Body Parkinson'S Disease 3 Autosomal Dominant Lewy Body Parkinson Disease 3 Autosomal Dominant Parkinson Disease 3 Parkinson Disease Type 3 Autosomal Dominant Parkinson Disease Parkinson Disease, Autosomal Dominant Parkinson Disease, Familial, Type 1
Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1	Guam Disease Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex Of Guam Als-Pdc Lytico-Bodig Disease Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Complex Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex 1, Susceptibility To Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex, Susceptibility To Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex Amyotrophic Lateral Sclerosis-Parkinsonism-Dementia Of Guam Syndrome Parkinsonism-Dementia-Als Complex Pdals Amyotrophic Lateral Sclerosis, Parkinsonism/Dementia Complex Of Guam Parkinson-Dementia Complex Of Guam G-Pdc Guam Parkinsonism-Dementia Complex ALS-PDC1 Als/Pdc Of Guam Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic/Parkinsonism/Dementia Complex 1 Amyotrophic Lateral Sclerosis, Guam Form Parkinsonian Disorders
Mucopolysaccharidosis-Plus Syndrome	Mucopolysaccharidosis Mucopolysaccharidosis-Like Syndrome With Congenital Heart Defects And Hematopoietic Disorders MPSPS Mucopolysaccharidoses Mps Mucopolysaccharidosis-Like Plus Disease Disorders Of Glycosaminoglycan Metabolism
Mucopolysaccharidosis Iii	Sanfilippo Syndrome Mucopolysaccharidosis Type Iii Mucopolysaccharidosis Type 3 Mps Iii Mpsiii Sanfilippo Disease Heparan Sulfate Sulfatase Deficiency Mucopolysaccharidosis, Mps-Iii N-Sulphoglucosamine Sulphohydrolase Deficiency Naglu Deficiency Sanfilippo'S Syndrome Mucopoly-Saccharidosis Type 3 Mps3 Sanfilippos Syndrome Mucopolysaccharidosis Type Iiia Mps Iii B
Parkinsonism	Parkinsonism-Plus Idiopathic Parkinsonism Primary Parkinsonism Paralysis Agitans Syndrome Parkinsonian Syndrome Trembling Paralysis Paralysis Agitans Shaking Palsy Shaking Paralysis
Creutzfeldt-Jakob Disease	Variant Creutzfeldt-Jakob Disease CJD Bovine Spongiform Encephalopathy Vcjd Inherited Creutzfeldt-Jakob Disease Creutzfeldt-Jakob Disease, Familial Creutzfeldt Jakob Disease Creutzfeldt-Jacob Disease Creutzfeldt Jacob Disease Sporadic Creutzfeldt-Jakob Disease Encephalopathy, Bovine Spongiform Creutzfeldt-Jakob Disease, Variant, Resistance To Creutzfeldt-Jakob Disease, Variant Creutzfeldt Jacob Syndrome Jakob-Creutzfeldt Disease Subacute Spongiform Encephalopathy Transmissible Virus Dementia New Variant Of Cjd Nv-Cjd Variant Cjd Variant Creutzfeldt-Jacob Disease Sporadic Cjd Inherited Cjd Acquired Creutzfeldt-Jakob Disease Variant Mcj Encephalopathy Bovine Spongiform Familial Creutzfeldt-Jakob Disease Creutzfeldt-Jakob Syndrome New Variant Creutzfeldt-Jakob Disease Creutzfeldt-Jakob Disease, Sporadic Acquired Cjd Scjd - [Sporadic Creutzfeldt-Jakob Disease] Idiopathic Creutzfeldt-Jakob Disease Creutzfeld-Jakob Disease Nos Vcjd - [Variant Creutzfeldt-Jakob Disease]
Spinocerebellar Ataxia 1	Spinocerebellar Ataxia Type 1 SCA1 Olivopontocerebellar Atrophy I Opca1 Opca4 Menzel Type Opca Schut-Haymaker Type Opca Spinocerebellar Atrophy I Opca I Olivopontocerebellar Atrophy Iv Opca Iv Cerebelloparenchymal Disorder I Cpd1 Olivopontocerebellar Atrophy 1 Cerebelloparenchymal Disorder 1 Olivopontocerebellar Atrophy 4 Spinocerebellar Atrophy 1 Type 1 Spinocerebellar Ataxia Spinocerebellar Ataxia-1 Ataxia, Spinocerebellar, Type 1
Mitochondrial Complex I Deficiency, Nuclear Type 1	Mitochondrial Complex I Deficiency Nadh:Q(1) Oxidoreductase Deficiency MC1DN1 Nadh-Coenzyme Q Reductase Deficiency Isolated Mitochondrial Respiratory Chain Complex I Deficiency Isolated Nadh-Coenzyme Q Reductase Deficiency Isolated Nadh-Coq Reductase Deficiency Isolated Nadh-Ubiquinone Reductase Deficiency Mitochondrial Nadh Dehydrogenase Component Of Complex I, Deficiency Of Nuclear Type Mitochondrial Complex I Deficiency 1 Isolated Complex I Deficiency Complex 1 Mitochondrial Respiratory Chain Deficiency Nadh Coenzyme Q Reductase Deficiency Complex I Mitochondrial Respiratory Chain Deficiency Deficiency Of Mitochondrial Nadh Dehydrogenase Component Of Complex I Nadh:Ubiquinone Oxidoreductase Deficiency Complex I, Mitochondrial Respiratory Chain, Deficiency Of
Aceruloplasminemia	Cerebellar Ataxia Hypoceruloplasminemia Hemosiderosis, Systemic, Due To Aceruloplasminemia Familial Apoceruloplasmin Deficiency Hereditary Ceruloplasmin Deficiency Deficiency Of Ferroxidase Hypoceruloplasminemia, Hereditary Ceruloplasmin Deficiency Systemic Hemosiderosis Due To Aceruloplasminemia ACERULOP
Atypical Autism	Pdd
Perry Syndrome	Parkinsonism With Alveolar Hypoventilation And Mental Depression PERRYS
Intellectual Developmental Disorder, Autosomal Dominant 55, With Seizures	MRD55 Mental Retardation, Autosomal Dominant 55, With Seizures Autosomal Dominant Mental Retardation 55 Autosomal Dominant Intellectual Developmental Disorder 55 Autosomal Dominant Intellectual Developmental Disorder-55 With Seizures Mental Retardation, Autosomal Dominant, Type 55, With Seizures
Movement Disease	Movement Disorders Movement Disorder
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Neurodegeneration With Brain Iron Accumulation 1	Pantothenate Kinase-Associated Neurodegeneration Pkan NBIA1 Hallervorden-Spatz Disease Hallervorden-Spatz Syndrome Pigmentary Pallidal Degeneration Neuroaxonal Dystrophy, Late Infantile Neurodegeneration With Brain Iron Accumulation Type 1 Classic Pantothenate Kinase-Associated Neurodegeneration Pkan Neuroaxonal Dystrophy, Juvenile-Onset Brain Iron Accumulation Type I Syndrome Nbia Neurodegeneration With Brain Iron Accumulation Nbia1, Classic Form Neurodegeneration With Brain Iron Accumulation Type 1, Classic Form Pkan, Classic Form Atypical Pantothenate Kinase-Associated Neurodegeneration Nbia1, Atypical Form Neurodegeneration With Brain Iron Accumulation Type 1, Atypical Form Pkan, Atypical Form Hss Pkan Neuroaxonal Dystrophy Juvenile-Onset Neurodegeneration, With Brain Iron Accumulation, Type 1
Parkinson Disease 4, Autosomal Dominant	Autosomal Dominant Parkinson Disease 4 PARK4 Parkinson Disease 4, Autosomal Dominant Lewy Body Parkinson Disease 4 Parkinson'S Disease 4 Autosomal Dominant Lewy Body Parkinson Disease 4 Autosomal Dominant Parkinson'S Disease 4 Parkinson Disease 4 Autosomal Dominant Lewy Body Parkinson Disease Autosomal Dominant 4 Parkinson Disease Familial Type 4 Parkinson Disease, Type 4
Schizophrenia	SCZD Schizophrenia With Or Without An Affective Disorder Schizophrenia 12 Schizophrenia, Susceptibility To Schizophrenia-1 Dementia Praecox Schizophrenia 1
Striatonigral Degeneration
Epilepsy, Familial Temporal Lobe, 8	Familial Temporal Lobe Epilepsy 8 ETL8 Epilepsy, Temporal Lobe, Familial, Type 8
Prion Disease	Spongiform Encephalopathy Transmissible Spongiform Encephalopathies Prion Diseases Prion Disease Pathway Transmissible Spongiform Encephalopathy Prion Induced Disorder Prion Protein Disease Inherited Human Transmissible Spongiform Encephalopathies Prion Protein Diseases Prion-Associated Disorders Prion-Induced Disorders Transmissible Dementias Tses Human Prion Disease Tse Encephalopathy, Transmissible Spongiform Prion Disease, Susceptibility To Spongiform Encephalopathies Human Transmissible Spongiform Encephalopathies, Inherited
Chronic Wasting Disease	Wasting Disease, Chronic
Parkinson Disease 15, Autosomal Recessive Early-Onset	Parkinsonian-Pyramidal Syndrome Pallidopyramidal Syndrome Parkinson Disease 15, Autosomal Recessive PARK15 Pkps Pallido-Pyramidal Syndrome Parkinson'S Disease 15 Autosomal Recessive Early-Onset Parkinson Disease 15 Autosomal Recessive Early-Onset Parkinson'S Disease 15 Pallido-Pyramidal Disease Parkinson Disease 15 Parkinson Disease 15 Autosomal Recessive Pps Parkinson Disease, Type 15
Autism Spectrum Disorder	Asd Autism Spectrum Disorders Autistic Continuum Pervasive Developmental Disorder Pervasive Development Disorder Autistic Behavior Autistic Disorder Autistic Autistic Disorder Of Childhood Onset Infantile Autism Childhood Autism Kanner Syndrome Pervasive Developmental Delay Nos Pervasive Developmental Disorder, Not Otherwise Specified
Myositis	Idiopathic Inflammatory Myopathy Idiopathic Inflammatory Myositis Iim Imm Idiopathic Inflammatory Myopathies Myopathy, Familial Idiopathic Inflammatory Inflammatory Disorder Of Muscle Idiopathic Inflammatory Myopathy, Familial Inflammatory Myopathy, Idiopathic Myopathies Idiopathic Inflammatory Familial Idiopathic Inflammatory Myopathy
Dysautonomia
Chromosomal Duplication Syndrome
Progressive Myoclonus Epilepsy	Pme Progressive Myoclonic Epilepsy Myoclonic Epilepsies, Progressive Unverricht-Lundborg Syndrome
Normal Pressure Hydrocephalus	Low Pressure Hydrocephalus Hydrocephalus Normal Pressure Hydrocephalus, Normal Pressure Normal Pressure Hydrocephalus Nos Nph - [Normal Pressure Hydrocephalus] Normal Pressure Hydrocephaly
Motor Neuron Disease	Anterior Horn Cell Disease Motor Neuron Diseases Mnd - [Motor Neurone Disease] Lou Gehrig Disease Creeping Palsy Creeping Paralysis Bulbar Motor Neuron Disease Bulbar Syndrome Anterior Horn Cell Disorder Hereditary Motor Neuron Disease
Dementia, Lewy Body	Lewy Body Dementia Lewy Body Disease Diffuse Lewy Body Disease Dementia With Lewy Bodies DLB Autosomal Dominant Diffuse Lewy Body Disease Cortical Lewy Body Disease Dementia, Lewy Body, Susceptibility To Lewy Body Dementia, Susceptibility To Senile Dementia Of The Lewy Body Type Dementia Of The Lewy Body Type Lbd Diffuse Lewy Body Disease With Gaze Palsy Dysphasic Dementia Hereditary Lewy Body Type Senile Dementia Lewy Body Variant Of Alzheimer Disease Lewy Bodies Lewy Body Dlbd - [Diffuse Lewy Body Disease] Clbd - [Cortical Lewy Body Disease]
Short Syndrome	Short Stature, Hyperextensibility, Hernia, Ocular Depression, Rieger Anomaly, And Teething Delay Aarskog-Ose-Pande Syndrome Lipodystrophy, Partial, With Rieger Anomaly And Short Stature Lipodystrophy-Rieger Anomaly-Diabetes Syndrome Rieger Anomaly-Partial Lipodystrophy Syndrome Partial Lipodystrophy With Rieger Anomaly And Short Stature Short Stature, Hyperextensibility, Hernia, Ocular Depression, Rieger Anomaly And Teething Delay Growth Retardation-Rieger Anomaly Short Stature-Hyperextensibility-Rieger Anomaly-Teething Delay SHORTS
Huntington Disease	Huntington'S Disease Huntington Chorea HD Huntington'S Chorea Huntington Chronic Progressive Hereditary Chorea Juvenile Huntington Disease Chronic Progressive Chorea Chronic Progressive Hereditary Chorea Hc - [Huntington Chorea] Hereditary Chorea Progressive Hereditary Chorea
Kufor-Rakeb Syndrome	Park9 Krppd KRS Pallidopyramidal Degeneration With Supranuclear Upgaze Paresis And Dementia Autosomal Recessive Parkinson Disease 9 Parkinson Disease 9 Parkinson Disease 9, Autosomal Recessive, Juvenile-Onset Autosomal Recessive Juvenile Onset Parkinson Disease 9 Parkinson Disease Type 9 Pallidopyramidal Degeneration With Supranuclear Upgaze Paresis, And Dementia Park 9 Atp13a2-Related Juvenile Neuronal Ceroid Lipofuscinosis Cln12 Disease Juvenile Parkinsonism-Neuronal Ceroid Lipofuscinosis Parkinson Disease Autosomal Recessive 9
Cerebellar Disease	Cerebellar Diseases Cerebellar Dysfunction Cerebellar Abnormality Cerebellar Disorders
Dialysis-Related Amyloidosis	Abeta2m Amyloidosis Amyloidosis Beta2m Beta2-Microglobulinic Amyloidosis Variant Abeta2m Amyloidosis Autosomal Dominant Beta2-Microglobulinic Amyloidosis Aβ2m Amyloidosis Dialysis-Related Beta2-Microglobulin Amyloidosis Amyloidosis Dialysis-Related Beta-2-Microglobulin Amyloidosis Dra Hemodialysis-Associated Amyloidosis
Cerebral Amyloid Angiopathy, Cst3-Related	Cerebral Amyloid Angiopathy Hereditary Cerebral Hemorrhage With Amyloidosis Hchwa Cerebral Amyloid Angiopathy, Familial Hereditary Cystatin C Amyloid Angiopathy Amyloidosis, Cerebroarterial, Icelandic Type Amyloidosis Vi Cerebral Hemorrhage, Hereditary, With Amyloidosis Cst3-Related Cerebral Amyloid Angiopathy Cerebral Hemorrhage, Hereditary, With Amyloidosis, Icelandic Variant Hereditary Cerebral Hemorrhage With Amyloidosis, Icelandic Variant Caa, Familial Cerebral Amyloid Angiopathy, Genetic Acys Amyloidosis Cst3-Related Amyloidosis Cystatin Amyloidosis Hchwa, Icelandic Type Hereditary Cerebral Hemorrhage With Amyloidosis, Icelandic Type Amyloidosis 6 AMYL6 Acys Caa Cerebral Amyloid Angiopathy Cst3-Related Cerebroarterial Amyloidosis Icelandic Type Cystatin C Amyloidosis Hccaa Hchwai Hchwa-I Hereditary Cerebral Hemorrhage With Amyloidosis Icelandic Type Cerebral Amyloid Angiopathy Familial Angiopathy, Amyloid, Cerebral, Cst3-Related Hereditary Cerebral Amyloid Angiopathy, Icelandic Type Familial Cerebral Amyloid Angiopathy Cerebral Amyloid Angiopathy, Hereditary
Gaucher'S Disease	Gaucher Disease Kerasin Thesaurismosis Glucocerebrosidase Deficiency Glucosylceramidase Deficiency Acid Beta-Glucosidase Deficiency Glucosylceramide Beta-Glucosidase Deficiency Acute Cerebral Gaucher Disease Cerebroside Lipidosis Syndrome Gaucher Splenomegaly Glucocerebrosidosis Glucosyl Cerebroside Lipidosis Kerasin Lipoidosis Lipoid Histiocytosis Glocucerebrosidase Deficiency Sphingolipidosis 1 Gaucher Syndrome Gauchers Disease Gd Glucosylceramide Lipidosis Kerasin Histiocytosis Gaucher Disease, Type 1 Gaucher Disease, Type 2
Alzheimer Disease 2	AD2 Alzheimer Disease Associated With Apoe4 Alzheimer'S Disease 2 Alzheimer Disease-2 Alzheimer Disease 2, Late-Onset Alzheimer Disease 2, Late Onset Late-Onset Alzheimer Disease Alzheimer Disease, Type 2 Alzheimer Disease, Late Onset
Von Economo'S Disease	Encephalitis Lethargica Von Economo Encephalitis Von Economo Disease
Spinal Muscular Atrophy	Sma 5q Sma Proximal Sma Sma-Associated Sma Spinal Amyotrophies Spinal Amyotrophy Spinal Muscle Degeneration Spinal Muscle Wasting Muscular Atrophy Spinal Atrophy, Muscular, Spinal Hereditary Motor Neuronopathy Progressive Muscular Atrophy Sma - [Spinal Muscular Atrophy]
Parkinson Disease 23, Autosomal Recessive Early-Onset	Autosomal Recessive Early-Onset Parkinson Disease 23 PARK23 Parkinson Disease 23, Autosomal Recessive, Early Onset Parkinson'S Disease 23 Autosomal Recessive Early-Onset Parkinson'S Disease 23 Parkinson Disease, Type 23, Autosomal Recessive, Early Onset
Communicating Hydrocephalus	Acquired Communicating Hydrocephalus
Essential Tremor	Benign Essential Tremor Familial Tremor Hereditary Essential Tremor Essential Hereditary Tremor Shaky Hand Syndrome Benign Essential Tremor Syndrome Tremor Hereditary Essential Essential Tremor, Susceptibility To Tremor, Hereditary Essential
Parkinson Disease 2, Autosomal Recessive Juvenile	Young-Onset Parkinson Disease PARK2 Pdj Autosomal Recessive Juvenile Parkinson Disease 2 Epdf Parkinson Disease, Juvenile, Type 2 Parkinson'S Disease 2 Autosomal Recessive Juvenile Parkinson Disease Early-Onset Parkinson Disease Parkinson Disease 2 Parkinson Disease, Juvenile, Autosomal Recessive Parkinsonism, Early-Onset, With Diurnal Fluctuation Autosomal Recessive Juvenile Parkinson'S Disease 2 Jp Juvenile Parkinsonism Parkinson Disease Autosomal Recessive, Early Onset Parkinsonism, Early Onset, With Diurnal Fluctuation Yopd Autosomal Recessive Early-Onset Parkinson Disease Type 2 Chromosome 6-Linked Autosomal Recessive Parkinsonism Early-Onset Parkinsonism With Diurnal Fluctuation Parkinsonism Young Adult Onset Parkinson Disease, Type 2 Parkinsonism, Juvenile
Vascular Parkinsonism
Spinal And Bulbar Muscular Atrophy, X-Linked 1	Kennedy Disease Sbma Spinal And Bulbar Muscular Atrophy Kennedy'S Disease X-Linked Spinal And Bulbar Muscular Atrophy SMAX1 Kd Kennedy Spinal And Bulbar Muscular Atrophy Spinobulbar Muscular Atrophy Bulbospinal Muscular Atrophy, X-Linked Bulbospinal Neuronopathy, X-Linked Recessive Xbsn Spinal And Bulbar Muscular Atrophy Of Kennedy Bulbospinal Muscular Atrophy X-Linked Bulbospinal Amyotrophy Bulbo-Spinal Atrophy, X-Linked Spinal Bulbar Muscular Atrophy X-Linked Bulbo-Spinal Atrophy X-Linked Spinal Bulbar Muscular Atrophy X-Linked Bsma X-Linked Bulbospinal Muscular Atrophy Spinal And Bulbar Muscular Atrophy X-Linked 1 Bulbospinal Muscular Atrophy X-Linked Bulbospinal Neuronopathy X-Linked Recessive Kennedy Disease) Kennedy Syndrome Atrophy, Muscular, Spinal And Bulbar, Kennedy Type Atrophy, Muscular, Spinobulbar Bulbospinal Neuronopathy
Krabbe Disease	Globoid Cell Leukodystrophy Galactosylceramide Beta-Galactosidase Deficiency Galc Deficiency Galactocerebrosidase Deficiency GLD Globoid Cell Leukoencephalopathy Diffuse Globoid Body Sclerosis Gcl Leukodystrophy, Globoid Cell Krabbe'S Leukodystrophy Krabbe Leukodystrophy KRB Beta Galactocerebrosidase Deficiency Krabbe'S Disease Galactosylceramidase Deficiency Disease Galactosylceramide Lipidosis Galactosylcerebrosidase Deficiency Galactosylsphingosine Lipidosis Psychosine Lipidosis Galactosylceramidase Deficiency Infantile Globoid Cell Leukodystrophy Krabbe Brain Sclerosis
Pseudobulbar Palsy	Pseudobulbar Paralysis
Frontotemporal Dementia	Pallidopontonigral Degeneration Frontotemporal Lobar Degeneration Semantic Dementia FTD Frontotemporal Lobe Dementia Multiple System Tauopathy With Presenile Dementia Dementia, Frontotemporal Frontotemporal Dementia With Parkinsonism Mstd Frontotemporal Lobar Degeneration With Tau Inclusions Ftld With Tau Inclusions Dementia, Frontotemporal, With Parkinsonism Fldem Ftdp17 Disinhibition-Dementia-Parkinsonism-Amyotrophy Complex Ddpac Wilhelmsen-Lynch Disease Wld Ppnd Dementia, Frontotemporal, With Or Without Parkinsonism Semantic Primary Progressive Aphasia Semantic Variant Ppa Wilhemsen-Lynch Disease Frontotemporal Dementia-Amyotrophic Lateral Sclerosis Frontotemporal Dementia And Parkinsonism Linked To Chromosome 17 Ftd-Als Ftld Pick Complex Pick Disease Of The Brain Frontotemporal Dementia With Parkinsonism-17 Grn-Related Frontotemporal Dementia Frontotemporal Dementia With Motor Neuron Disease Dementia In Fronto-Temporal Lobar Degeneration Ftd - [Frontotemporal Dementia] Temple Dementia Frontal Lobe Dementia
Aphasia
Gerstmann-Straussler Disease	Gerstmann-Straussler-Scheinker Disease Gerstmann-Straussler-Scheinker Syndrome Prion Dementia Cerebral Amyloid Angiopathy, Prnp-Related GSD Gss Cerebellar Ataxia, Progressive Dementia, And Amyloid Deposits In Cns Amyloidosis, Cerebral, With Spongiform Encephalopathy Subacute Spongiform Encephalopathy, Gerstmann-Straussler Type Encephalopathy, Subacute Spongiform, Gerstmann-Straussler Type Amyloidosis Cerebral With Spongiform Encephalopathy Cerebellar Ataxia, Progressive Dementia, And Amyloid Deposits In The Central Nervous System Encephalopathy Subacute Spongiform Gerstmann-Straussler Type Gssd Gerstmann Straussler Scheinker Syndrome Cerebral Amyloidosis With Spongiform Encephalopathy Subacute Spongiform Encephalopathy Gerstmann-Straussler Type Gluthathione Synthetase Deficiency Gerstmann Straussler Syndrome
Mucopolysaccharidosis, Type Iiia	Mucopolysaccharidosis Type Iiia MPS3A Mps Iiia Sanfilippo Syndrome A Heparan Sulfate Sulfatase Deficiency Sulfamidase Deficiency Heparan Sulfamidase Deficiency Mpsiiia Mucopolysaccharidosis Type 3a Sanfilippo Syndrome Type A Mucopolysaccharidosis Iii-A Heparane Sulfamidase Deficiency Mps 3a Mucopoly-Saccharidosis Type 3a Mps Iii-A Mucopolysaccharidosis 3a Mucopolysaccharidosis Iii
Autism	Autistic Disorder Autism Susceptibility 1 Childhood Autism Autistic Disorder Of Childhood Onset Infantile Autism Kanner'S Syndrome Autistic
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Impulse Control Disorder	Disruptive, Impulse Control, And Conduct Disorders
Amyloidosis	Amyloid Disease Amyloid Amyloid Degeneration Amyloidosis Nos Amyloid Deposition Amyloid Infiltration Idiopathic Amyloidosis Hyaloid Degeneration Lardaceous Degeneration
Pure Autonomic Failure	Orthostatic Hypotension Idiopathic Orthostatic Hypotension Postural Hypotension Bradbury-Eggleston Syndrome Bradbury Eggleston Syndrome Hypotension, Orthostatic Hypotension, Postural Paf Pure Dysautonomia Pure Idiopatic Dysautonomia Hypotension Orthostatic Primary Orthostatic Hypotension Chronic Orthostatic Hypotension
Hereditary Spastic Paraplegia	Familial Spastic Paraplegia Hereditary Spastic Paraparesis Strumpell-Lorrain Disease Hsp Spg Strümpell-Lorrain Disease Spastic Paraplegia, Hereditary French Settlement Disease Strumpell-Lorrain Syndrome Fsp Familial Spastic Paraparesis Spastic Paraplegia, Familial Spastic Paraplegia Hereditary Spastic Paraplegia 3, Autosomal Dominant Spastic Paraparesis Hereditary Spastic Paralysis Familial Spastic Paralysis Hereditary Spastic Ataxia
Central Nervous System Disease	CNS Cns Diseases Central Nervous System Diseases Cns Disorder
Machado-Joseph Disease	SCA3 MJD Spinocerebellar Ataxia 3 Azorean Disease Spinocerebellar Ataxia Type 3 Azorean Neurologic Disease Spinopontine Atrophy Nigrospinodentatal Degeneration Spinocerebellar Atrophy Spinocerebellar Atrophy Iii Spinocerebellar Atrophy Type 3 Azorean Ataxia Azorean Disease Of The Nervous System Machado Disease Nigro-Spino-Dentatal Degeneration With Nuclear Ophthalmoplegia Disease, Machado-Joseph Ataxia, Spinocerebellar
Central Neurocytoma	Neurocytoma Neurolipocytoma Neurocytoma Central
Charcot-Marie-Tooth Disease	Cmt Hmsn Hereditary Motor And Sensory Neuropathy Pma Cmt - Charcot-Marie-Tooth Disease Charcot Marie Tooth Disease Charcot-Marie-Tooth Hereditary Neuropathy Charcot-Marie-Tooth Syndrome Peroneal Muscular Atrophy Hereditary Motor And Sensory Neuropathies
Fatal Familial Insomnia	Insomnia, Fatal Familial FFI Familial Fatal Insomnia Insomnia Familial Fatal Insomnia Fatal Familial Insomnia, Fatal, Familial Ffi - [Fatal Familial Insomnia]
Rem Sleep Behavior Disorder	Rem Sleep Behaviour Disorder Rapid Eye Movement Sleep Behavior Disorder Rapid Eye Movement Sleep Behaviour Disorder Rem - [Rapid Eye Movement] Behaviour Disorder
Akinetic Mutism	Coma Vigilans
Vascular Dementia	Dementia, Vascular Multi Infarct Dementia Multifocal Dementia Dementia Vascular Vascular Dementia, Susceptibility To Dementia, Multi-Infarct Multi-Infarct Dementia
Constipation
Pick Disease Of Brain	Pick Disease Pick Disease Of The Brain Lobar Atrophy Of Brain Dementia With Lobar Atrophy And Neuronal Cytoplasmic Inclusions Pick'S Disease Behavioral Variant Of Frontotemporal Dementia Dementia In Pick'S Disease Lobar Atrophy Of The Brain Bvftd Bv-Ftd PIDB Picks Disease
Neurodegeneration With Brain Iron Accumulation	Nbia Neurodegeneration With Brain Iron Accumulation Disorders Neurodegeneration, With Brain Iron Accumulation
Parkinson Disease 1, Autosomal Dominant	Autosomal Dominant Parkinson Disease 1 PARK1 Parkinson Disease 1 Parkinson'S Disease 1 Atypical Parkinson Disease Parkinson Disease 1, Autosomal Dominant Lewy Body Autosomal Dominant Parkinson'S Disease 1 Lewy Body Parkinsonism Parkinson Disease Autosomal Dominant 1 Parkinson Disease Familial Type 1 Parkinson Disease, Type 1 Parkinson Disease, Familial, Type 1
Gaucher Disease, Type I	Glucocerebrosidase Deficiency Acid Beta-Glucosidase Deficiency Gba Deficiency GD1 Gd I Gaucher Disease, Noncerebral Juvenile Gaucher Disease Type 1 Gaucher Disease Type I Gaucher'S Disease Type I Gaucher Disease Gd 1 Non-Cerebral Juvenile Gaucher Disease GD Gaucher Disease 1 Adult Non-Neuronopathic Gaucher Disease Noncerebral Juvenile Gaucher Disease Type 1 Gaucher Disease Gaucher Disease, Type 1
Cardiac Arrest	Cardiopulmonary Arrest Circulatory Arrest Heart Arrest
Hereditary Late-Onset Parkinson Disease	Autosomal Dominant Late-Onset Parkinson Disease Lopd Hereditary Late Onset Parkinson Disease
Scrapie
Restless Legs Syndrome	Wed Willis-Ekbom Disease Restless Leg Syndrome Ekbom Syndrome Wittmaack-Ekbom Syndrome Willis Ekbom Disease Ekbom'S Syndrome Rls Restless Legs Restless Legs Syndrome, Susceptibility To
Postencephalitic Parkinson Disease	Postencephalitic Parkinsonism Parkinson Disease, Postencephalitic
Alcohol Dependence	Alcoholism Alcohol Dependence, Susceptibility To Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against Alcohol Dependence, Protection Against Alcoholism, Susceptibility To Alcoholic Intoxication, Chronic Pharyngeal Neoplasms Chronic Alcoholism Dipsomania Alcohol Addiction Ethanol Dependence Chronic Ethanolism Chronic Alcoholic Disease Nos Alcoholic Disease Nos Alcoholic
Capgras Syndrome	Capgras Delusion Theory
Dopamine Beta-Hydroxylase Deficiency	Noradrenaline Deficiency Norepinephrine Deficiency Dopamine Beta Hydroxylase Deficiency Congenital Dopamine Beta-Hydroxylase Deficiency Dopamine Beta-Hydroxylase Deficiency, Congenital Dopamine Β-Hydroxylase Dbh Deficiency
Niemann-Pick Disease, Type C1	Niemann-Pick Disease, Type C NPC1 Niemann-Pick Disease, Type D Niemann-Pick Disease Type C1 Niemann-Pick Disease With Cholesterol Esterification Block Niemann-Pick Disease, Subacute Juvenile Form Neurovisceral Storage Disease With Vertical Supranuclear Ophthalmoplegia Npc Niemann-Pick Disease, Chronic Neuronopathic Form Niemann-Pick Disease Without Sphingomyelinase Deficiency Niemann-Pick Disease Type C Niemann-Pick Disease Type D Niemann-Pick C1 Disease Niemann-Pick Disease C1 Niemann-Pick Disease Chronic Neuronopathic Form Niemann-Pick Disease Nova Scotian Type Niemann-Pick Disease Subacute Juvenile Form Niemann-Pick Disease Type Ii Niemann-Picks Disease Type C
Attention Deficit-Hyperactivity Disorder	Attention Deficit Hyperactivity Disorder ADHD Attention Deficit Disorder Attention Deficit-Hyperactivity Disorder, Susceptibility To Attention Deficit Disorder With Hyperactivity Hyperkinetic Disorder Hyperactivity Of Childhood Attention-Deficit/Hyperactivity Disorder Add Addh Attention Deficit Attention Deficit Disorder Of Childhood With Hyperactivity Attention Deficit Disorder With Hyperactivity Syndrome Hyperkinetic Syndrome Attention-Deficit Hyperactivity Disorder Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type Disturbance Of Activity And Attention Disorder Of Activity And Attention Adhd - [Attention Deficit Hyperactivity Disorder] Hyperkinetic Disorders Disorder Of Activity And Attention With Hyperkinesia Attention Deficit Syndrome With Hyperactivity

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P990898	Amlenetug		99.85%	Phase 3

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-135902A	Synucleozid hydrochloride	Inhibitor	98.23%	Unkown
HY-135902	Synucleozid	Inhibitor	/	Unkown
HY-125984	Syn-516	Inhibitor	/	Unkown
HY-401209	Synucleozid-2.0	Inhibitor	98.01%	Unkown
HY-RS13482	SNCA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13483	Snca Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS13484	Snca Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990922	Indenebart		99.53%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SNCA	VGNC	VGNC:35059
Mus musculus	SNCA	MGD	MGI:1277151
Macaca mulatta	SNCA	VGNC	VGNC:77668
Rattus norvegicus	SNCA	RGD	RGD:3729
Canis familiaris	SNCA	VGNC	VGNC:46596
Others	SNCA	NCBI