PRMT5-IN-47
PRMT5-IN-47 (compound 20) is a potent, selectively and orally active, MTA cooperative PRMT5 inhibitor with an IC50 value of 15 nM. PRMT5-IN-47 shows antiproliferative activity. PRMT5-IN-47 shows anticancer activity.
For research use only. We do not sell to patients.
- CAS No.: 3065081-87-7
- Formula: C24H22FN5O2
- Molecular Weight:431.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Histone Methyltransferase Isoforms
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Biological Activity
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PRMT5 15 nM (IC50) |
Chemical Information
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CAS No. 3065081-87-7
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Molecular Weight 431.46
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Formula C24H22FN5O2
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SMILES
NC1=NC2=C(C=C(C(F)=C2)C(N(C)[C@H]3CN(CC3)C4=CC=C(C=C4)C#N)=O)C5=C1COC5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)