country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187044

Copy Link Print Information

S-16018

S-16018 is the N-demethylated metabolite of S 16020. S 16020 is an anticancer agent.

For research use only. We do not sell to patients.

CAS No.: 156055-44-6
Formula: C₂₁H₂₂N₄O₂
Molecular Weight:362.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

S-16018 Chemical Structure

CAS No.: 156055-44-6

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

S-16018 is the N-demethylated metabolite of S 16020. S 16020 is an anticancer agent^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
L1210	IC₅₀	4.9 nM Compound: 17	In vitro cytotoxicity against L1210 (murine leukemia) cells. In vitro cytotoxicity against L1210 (murine leukemia) cells.	[PMID: 8057291]
MC-38	IC₅₀	22 nM Compound: 17	Tested for cytotoxicity against C38 cell lines measured by MAT assay Tested for cytotoxicity against C38 cell lines measured by MAT assay	[PMID: 8057291]

Chemical Information

CAS No. 156055-44-6
Molecular Weight 362.43
Formula C₂₁H₂₂N₄O₂
SMILES

O=C(NCCN(C)C)C1=NC=CC2=C1C=C3C=4C=C(O)C=CC4NC3=C2C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Awada A, et al. Clinical phase I and pharmacokinetic study of S 16020, a new olivacine derivative: report on three infusion schedules. Annals of oncology : official journal of the European Society for Medical Oncology. 2002 Dec;13(12):1925-34. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote