1. Epigenetics
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. JAK
  3. JAK3 covalent inhibitor-1

JAK3 covalent inhibitor-1 

Cat. No.: HY-119935
Handling Instructions

JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs.

For research use only. We do not sell to patients.

JAK3 covalent inhibitor-1 Chemical Structure

JAK3 covalent inhibitor-1 Chemical Structure

CAS No. : 2300106-50-5

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Description

JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs[1].

IC50 & Target[1]

JAK3

11 nM (IC50)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

448.47

Formula

C₂₂H₁₇FN₆O₂S

CAS No.

2300106-50-5

SMILES

O=S(N[[email protected]](C[[email protected]@H]1NC#N)C(C1=C2)=CC=C2C3=C4C(NC=C4)=NC=N3)(C5=CC=CC(F)=C5)=O

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
JAK3 covalent inhibitor-1
Cat. No.:
HY-119935
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JAK3 covalent inhibitor-1

Cat. No.: HY-119935