JBP485
Based on 1 Customer Validation
JBP485 (cyclo-trans-4-L-hydroxyprolyl-L-serine) is a dipeptide with anti-hepatotoxic and wound healing properties. JBP485 can be used for research of various kinds of corneal epithelial diseases.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 211868-63-2
- Formula: C8H12N2O4
- Molecular Weight:200.19
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
JBP485 (1-100 μM, 24-96 h) accelerates proliferation of cultivated corneal epithelial cells (CECs) dose- and time-dependently[1].
JBP485 (1-100 μM, 15 h) accelerates migration of CECs dose-dependently[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 211868-63-2
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Appearance Solid
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Molecular Weight 200.19
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Formula C8H12N2O4
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Color Light yellow to yellow
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SMILES
O=C(N[C@H]1CO)[C@@](C[C@@H](O)C2)([H])N2C1=O
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Synonyms
cyclo(L-Hyp-L-Ser)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 7.5 mg/mL (37.46 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9953 mL | 24.9763 mL | 49.9525 mL | 124.8814 mL |
| 5 mM | 0.9991 mL | 4.9953 mL | 9.9905 mL | 24.9763 mL | |
| 10 mM | 0.4995 mL | 2.4976 mL | 4.9953 mL | 12.4881 mL | |
| 15 mM | 0.3330 mL | 1.6651 mL | 3.3302 mL | 8.3254 mL | |
| 20 mM | 0.2498 mL | 1.2488 mL | 2.4976 mL | 6.2441 mL | |
| 25 mM | 0.1998 mL | 0.9991 mL | 1.9981 mL | 4.9953 mL | |
| 30 mM | 0.1665 mL | 0.8325 mL | 1.6651 mL | 4.1627 mL |