1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. JBP485

JBP485 (cyclo-trans-4-L-hydroxyprolyl-L-serine) is a dipeptide with anti-hepatotoxic and wound healing properties. JBP485 can be used for research of various kinds of corneal epithelial diseases.

For research use only. We do not sell to patients.

JBP485 Chemical Structure

JBP485 Chemical Structure

CAS No. : 211868-63-2

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Description

JBP485 (cyclo-trans-4-L-hydroxyprolyl-L-serine) is a dipeptide with anti-hepatotoxic and wound healing properties. JBP485 can be used for research of various kinds of corneal epithelial diseases[1].

In Vitro

JBP485 (1-100 μM, 24-96 h) accelerates proliferation of cultivated corneal epithelial cells (CECs) dose- and time-dependently[1].
JBP485 (1-100 μM, 15 h) accelerates migration of CECs dose-dependently[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

JBP485 (100 μM, topical application, 4 times per day) accelerates the corneal epithelial wound healing on rabbits (4 days for healing completely, compared with 5 days for control group)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

200.19

Formula

C8H12N2O4

CAS No.
SMILES

O=C(N[C@H]1CO)[C@@](C[C@@H](O)C2)([H])N2C1=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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JBP485 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
JBP485
Cat. No.:
HY-135627
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