JMV 179
JMV 179, a peptide closely related to CCK, is a cholecystokinin receptor (CKK) antagonist, with an IC50 of 30 nM.
For research use only. We do not sell to patients.
- CAS No.: 119386-87-7
- Formula: C51H67N7O15S
- Molecular Weight:1050.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 119386-87-7
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Molecular Weight 1050.18
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Formula C51H67N7O15S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. K Kennedy, et al. Identification of two amino acids of the human cholecystokinin-A receptor that interact with the N-terminal moiety of cholecystokinin. J Biol Chem. 1997 Jan 31;272(5):2920-6. [Content Brief]
[2]. S Silvente Poirot, et al. Study of the states and populations of the rat pancreatic cholecystokinin receptor using the full peptide antagonist JMV 179. Eur J Biochem. 1993 Mar 1;212(2):529-38. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)