aStAx-35R
aStAx-35R, a stapled peptide, antagonizes nuclear form of β-catenin and inhibits Wnt signaling. aStAx-35R inhibits competitively the binding of β-catenin to TCF4. aStAx-35R selectively induces growth inhibition of Wnt-dependent cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 1418863-17-8
- Formula: C111H178N40O20
- Molecular Weight:2392.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 1418863-17-8
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Molecular Weight 2392.86
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Formula C111H178N40O20
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Sequence
Ac-Arg-Arg-Trp-Pro-Arg-S5-Ile-Leu-Asp-S5-His-Val-Arg-Arg-Val-Trp-Arg-NH2
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Sequence Shortening
Ac-RRWPR-S5-ILD-S5-HVRRVWR-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Topics How Wnt Signaling Preserves Stem Cell Renewal
How Wnt signaling preserves stem cell renewal describes how Wnt-regulated pathways maintain stem cell self-renewal, proliferation, quiescence, and differentiation balance in specialized stem cell niches.
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Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)