2-Hydroxy Ibuprofen
2-Hydroxy Ibuprofen ((±)-2-Hydroxy Ibuprofen) is a major oxidative metabolite of Ibuprofen (HY-78131). 2-Hydroxy Ibuprofen undergoes phase II metabolism, forming a β-1-O-acyl glucuronide conjugate at the carboxyl group of its propionic acid side chain. 2-Hydroxy Ibuprofen can be used for metabolism-related research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 51146-55-5
- 分子式: C13H18O3
- 分子量:222.28
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
2‑Hydroxy Ibuprofen can generate a β‑1‑O‑acyl glucuronide conjugate at the carboxylic acid site of the propionic acid side chain during Phase II metabolism[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 51146-55-5
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分子量 222.28
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分子式 C13H18O3
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SMILES
O=C(O)C(C)C1=CC=C(CC(C)(O)C)C=C1
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別名
(±)-2-Hydroxy Ibuprofen
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- 2-Hydroxy Ibuprofen
- 51146-55-5
- (±)-2-Hydroxy Ibuprofen
- Drug Metabolite
- Drug Intermediate
- β-1-O-acyl glucuronide conjugate
- propionic acid side chain carboxylic group
- human urine
- phase II metabolism
- ibuprofen metabolite
- isobutyl side chain hydroxylation
- rainbow trout
- activated sludge
- sewage wastewater
- phase I ibuprofen metabolite
- Inhibitor
- inhibitor
- inhibit