2-Hydroxybenzimidazole
Based on 1 Customer Validation
2-Hydroxybenzimidazole is an inactive compound targeting CYP1A1 and is mainly used as a control compound in the structure-activity relationship study of benzimidazole derivatives. 2-Hydroxybenzimidazole does not have the ability to induce CYP1A1 expression like its thiol or amino substituted derivatives.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.98%
- CAS 番号: 615-16-7
- 分子式: C7H6N2O
- 分子量:134.14
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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Metabolism/Protease Compound Library
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生物活性
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CYP1A1 |
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Cell Line
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Type | Value | Description | References |
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| HEK293 | IC50 |
>100 μM
Compound: 7
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Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay
Inhibition of human recombinant DAAO expressed in HEK293 cells using D-serine as substrate after 20 mins by horseradish peroxidase-coupled assay
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[PMID: 23243487] |
化学情報
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CAS 番号 615-16-7
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性状 Solid
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分子量 134.14
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分子式 C7H6N2O
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Color Off-white to light brown
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SMILES
O=C1NC2=CC=CC=C2N1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 50 mg/mL (372.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (392 KB)
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- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.4549 mL | 37.2745 mL | 74.5490 mL | 186.3724 mL |
| 5 mM | 1.4910 mL | 7.4549 mL | 14.9098 mL | 37.2745 mL | |
| 10 mM | 0.7455 mL | 3.7274 mL | 7.4549 mL | 18.6372 mL | |
| 15 mM | 0.4970 mL | 2.4850 mL | 4.9699 mL | 12.4248 mL | |
| 20 mM | 0.3727 mL | 1.8637 mL | 3.7274 mL | 9.3186 mL | |
| 25 mM | 0.2982 mL | 1.4910 mL | 2.9820 mL | 7.4549 mL | |
| 30 mM | 0.2485 mL | 1.2425 mL | 2.4850 mL | 6.2124 mL | |
| 40 mM | 0.1864 mL | 0.9319 mL | 1.8637 mL | 4.6593 mL | |
| 50 mM | 0.1491 mL | 0.7455 mL | 1.4910 mL | 3.7274 mL | |
| 60 mM | 0.1242 mL | 0.6212 mL | 1.2425 mL | 3.1062 mL | |
| 80 mM | 0.0932 mL | 0.4659 mL | 0.9319 mL | 2.3297 mL | |
| 100 mM | 0.0745 mL | 0.3727 mL | 0.7455 mL | 1.8637 mL |
2-Hydroxybenzimidazole 関連分類
HY-W008003 関連分類
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