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製品番号: HY-W702106

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2-Methyl estradiol

2-Methyl estradiol, an endogenous metabolite of Estradiol (HY-B0141), inhibits cell proliferation and angiogenesis, with IC₅₀ values of 3 and 2.39 μM for HUVEC and MCF-7 human breast cancer cell proliferation, respectively.

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CAS 番号: 1818-12-8
分子式: C₁₉H₂₆O₂
分子量:286.41

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

2-Methyl estradiol 構造式

CAS 番号: 1818-12-8

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Endogenous Metabolite アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
DU-145	GI₅₀	16 μM Compound: 9	Cytotoxicity against prostate DU-145 cancer cell lines. Cytotoxicity against prostate DU-145 cancer cell lines.	[PMID: 7783135]
DU-145	GI₅₀	51 μM Compound: 8	Antiproliferative activity against human DU145 cells after 96 hrs by WST1 assay Antiproliferative activity against human DU145 cells after 96 hrs by WST1 assay	[PMID: 17696419]
HCT-116	GI₅₀	3.6 μM Compound: 9	Cytotoxicity against colon HCT116 cancer cell lines. Cytotoxicity against colon HCT116 cancer cell lines.	[PMID: 7783135]
HOP-62	GI₅₀	11 μM Compound: 9	Cytotoxicity against lung HOP-62 cancer cell lines. Cytotoxicity against lung HOP-62 cancer cell lines.	[PMID: 7783135]
MDA-MB-435	GI₅₀	1.8 μM Compound: 9	Cytotoxicity against breast MDA-MB-435 cancer cell lines. Cytotoxicity against breast MDA-MB-435 cancer cell lines.	[PMID: 7783135]
OVCAR-3	GI₅₀	9.1 μM Compound: 9	Cytotoxicity against ovarian OVCAR-3 cancer cell lines. Cytotoxicity against ovarian OVCAR-3 cancer cell lines.	[PMID: 7783135]
Panel (Carcinoma cell lines)	GI₅₀	8.1 μM Compound: 9	Mean graph midpoint for all human cancer cell line cytotoxicity. Mean graph midpoint for all human cancer cell line cytotoxicity.	[PMID: 7783135]
SF-539	GI₅₀	7.4 μM Compound: 9	Cytotoxicity against CNS SF-539 cancer cell lines. Cytotoxicity against CNS SF-539 cancer cell lines.	[PMID: 7783135]
SN12C	GI₅₀	17 μM Compound: 9	Cytotoxicity against renal SN12C cancer cell lines. Cytotoxicity against renal SN12C cancer cell lines.	[PMID: 7783135]
UACC-62	GI₅₀	5.4 μM Compound: 9	Cytotoxicity against melanoma UACC-62 cancer cell lines. Cytotoxicity against melanoma UACC-62 cancer cell lines.	[PMID: 7783135]

化学情報

CAS 番号 1818-12-8
分子量 286.41
分子式 C₁₉H₂₆O₂
SMILES

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC(C)=C(O)C=C4CC3
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (268 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Iljung Lee, et al. 2-[methyl-(11)C]methoxyestradiol: synthesis, evaluation and pharmacokinetics for in vivo studies on angiogenesis. Nucl Med Biol. 2007 Aug;34(6):625-31. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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