3-Phosphoglyceric acid
Based on 1 Customer Validation
3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.88%
- CAS 番号: 820-11-1
- 分子式: C3H7O7P
- 分子量:186.06
-
保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-Y0781
Pyruvic acidEndogenous Metabolite -
HY-151223
D-Glyceraldehyde 3-phosphateEndogenous Metabolite -
HY-112537
D-Glucose 6-phosphateEndogenous Metabolite -
HY-B0389
D-GlucoseMonosaccharide -
HY-113407A
D-Fructose-6-phosphate disodiumEndogenous Metabolite -
HY-W013636
2-Ketoglutaric acidKrebs Cycle Intermediate -
HY-B2227
Lactic acidGlycolysis Production -
HY-Y0966
GlycineNMDAR Agonist -
HY-B2176
ATPEndogenous Metabolite -
HY-W015913
Pyruvic acid sodiumGlycolysis Intermediate -
HY-W008807
Phosphoenolpyruvic acid potassiumGlycolysis Metabolite -
HY-113128A
sn-Glycerol 3-phosphate lithiumEndogenous Metabolite
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
IC50 & Target
|
Human Endogenous Metabolite |
体外実験
3-Phosphoglyceric acid (400 μM; 24 hours; BMDMs) treatment enhances Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification is also reversed[1].
3-Phosphoglyceric treatment significantly augmentes gene expression as well as H3K4me3 deposition of Spp1 in IL-4-stimulated macrophages[1].
In yeast, 3-Phosphoglyceric acid acts as a metabolic checkpoint for the formation of a multicomponent enzyme complex including serine metabolic enzymes and pyruvate kinase isoform 2 (PKM2) homologue, which senses both serine metabolism and glycolysis and regulates H3K4 methylation and histone phosphorylation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:Bone marrow-derived macrophages (BMDMs)
-
Concentration:400 µM
-
Incubation Time:24 hours
-
Result:Enhanced Spp1 transcription in VHL-deficient macrophages, and the reduced H3K4me3 modification was also reversed.
化学情報
-
CAS 番号 820-11-1
-
性状 Viscous Liquid
-
分子量 186.06
-
分子式 C3H7O7P
-
Color Colorless to light yellow
-
SMILES
O=C(O)C(O)COP(O)(O)=O
-
別名
3-PGA; 3-Glycerophosphoric acid
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
H2O : 100 mg/mL (537.46 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (271 KB)
-
SDS (477 KB)
- English - EN (477 KB)
- Français - FR (477 KB)
- Deutsch - DE (477 KB)
- Norwegian - NO (477 KB)
- Español - ES (477 KB)
- Swedish - SV (477 KB)
- Italian - IT (477 KB)
- Korean - KR (477 KB)
- Portuguese - PT (477 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.3746 mL | 26.8731 mL | 53.7461 mL | 134.3653 mL |
| 5 mM | 1.0749 mL | 5.3746 mL | 10.7492 mL | 26.8731 mL | |
| 10 mM | 0.5375 mL | 2.6873 mL | 5.3746 mL | 13.4365 mL | |
| 15 mM | 0.3583 mL | 1.7915 mL | 3.5831 mL | 8.9577 mL | |
| 20 mM | 0.2687 mL | 1.3437 mL | 2.6873 mL | 6.7183 mL | |
| 25 mM | 0.2150 mL | 1.0749 mL | 2.1498 mL | 5.3746 mL | |
| 30 mM | 0.1792 mL | 0.8958 mL | 1.7915 mL | 4.4788 mL | |
| 40 mM | 0.1344 mL | 0.6718 mL | 1.3437 mL | 3.3591 mL | |
| 50 mM | 0.1075 mL | 0.5375 mL | 1.0749 mL | 2.6873 mL | |
| 60 mM | 0.0896 mL | 0.4479 mL | 0.8958 mL | 2.2394 mL | |
| 80 mM | 0.0672 mL | 0.3359 mL | 0.6718 mL | 1.6796 mL | |
| 100 mM | 0.0537 mL | 0.2687 mL | 0.5375 mL | 1.3437 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
3-Phosphoglyceric acid 関連分類
HY-113491 関連分類
Powered by Bioz