4'-Demethyleucomin
4'-Demethyleucomin (O-Demethyleucomin) is a Sesquiterpenoids product that can be isolated from the herbs of Polygonum hydropiper.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 34818-83-2
- 分子式: C16H12O5
- 分子量:284.26
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 3T3-L1 | IC50 |
>100 μM
Compound: 9
|
Antiadipogenic activity against mouse 3T3L1 cells assessed as inhibition of differentiation after 7 days by oil-red O staining
Antiadipogenic activity against mouse 3T3L1 cells assessed as inhibition of differentiation after 7 days by oil-red O staining
|
[PMID: 19757853] |
| ARPE-19 | GI50 |
>100 μM
Compound: 34
|
Antiproliferative activity against human ARPE19 assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
Antiproliferative activity against human ARPE19 assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
|
[PMID: 30951308] |
| BTI-TN-5B1-4 | IC50 |
11.46 μM
Compound: 1h
|
Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorimetric method
Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorimetric method
|
[PMID: 21405131] |
| BTI-TN-5B1-4 | IC50 |
8.61 nM
Compound: 1h
|
Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorimetric method
Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI-TN-5B1-4 insect sells assessed as hydrogen peroxide production by fluorimetric method
|
[PMID: 21405131] |
| HT-29 | IC50 |
>20 μM
Compound: 11
|
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth incubated for 72 hrs
Cytotoxicity against human HT-29 cells assessed as reduction in cell growth incubated for 72 hrs
|
[PMID: 26147490] |
| MDA-MB-435 | IC50 |
>20 μM
Compound: 11
|
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell growth incubated for 72 hrs
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell growth incubated for 72 hrs
|
[PMID: 26147490] |
| Y79 | GI50 |
>100 μM
Compound: 34
|
Cytotoxicity against human Y79 cells assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
Cytotoxicity against human Y79 cells assessed as reduction in cell number incubated for 44 hrs by alamar blue based fluorescence assay
|
[PMID: 30951308] |
化学情報
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CAS 番号 34818-83-2
-
分子量 284.26
-
分子式 C16H12O5
-
SMILES
O=C1/C(COC2=CC(O)=CC(O)=C12)=C/C3=CC=C(O)C=C3
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別名
O-Demethyleucomin
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Structure Classification
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)