4-Hydroxytryptophol
4-Hydroxytryptophol is an in vitro metabolite of psilocin, can be found in human liver microsomes and recombinant monoamine oxidase A systems. 4-Hydroxytryptophol is not detected in in vivo samples from mice or humans.
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- CAS 番号: 1379213-90-7
- 分子式: C10H11NO2
- 分子量:177.20
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
4-Hydroxytryptophol is produced in minor amounts (43.4 nM) alongside a 29% decrease in psilocin concentration when 1,000 nM psilocin is incubated with human liver microsomes for 240 minutes[1].
4-Hydroxytryptophol is produced in minor amounts (16.9 nM) without a visible decrease in psilocin concentration when 1,000 nM psilocin is incubated with recombinant MAO-A enzymes for 300 minutes[1].
4-Hydroxytryptophol shows no relevant binding affinity to human 5-HT1A, 5-HT2A, and 5-HT2C receptors (Ki > 10,000 nM) in HEK 293 cell line membrane preparations[1].
4-Hydroxytryptophol shows no relevant activation potency at human 5-HT1A, 5-HT2A, and 5-HT2B receptors (EC50 > 10,000 nM) in NIH/3T3 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1379213-90-7
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分子量 177.20
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分子式 C10H11NO2
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SMILES
OC1=CC=CC2=C1C(CCO)=CN2
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別名
4-HTP
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)