4'-Nitroacetophenone
Based on 1 Customer Validation
4'-Nitroacetophenone is a nitroaromatic compound. 4'-Nitroacetophenone is an important organic synthetic intermediate, which can be used for the synthesis of other active compounds such as Chloramphenicol (HY-B0239).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.69%
- CAS 番号: 100-19-6
- 分子式: C8H7NO3
- 分子量:165.15
-
保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
4'-Nitroacetophenone derivatives exhibit multiple activities, such as anti-trypanosoma cruzi and α-glucosidase inhibition[2][3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 100-19-6
-
性状 Solid
-
分子量 165.15
-
分子式 C8H7NO3
-
Color Light yellow to yellow
-
SMILES
CC(C1=CC=C([N+]([O-])=O)C=C1)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (605.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (272 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
取扱説明書 (2659 KB)
参考文献
[1]. KLOSA J. et al [Studies on the exchange of diazonium group with nitro group for the preparation of p-nitroacetophenone. III. Synthesis of chloramphenicol]. Arch Pharm Ber Dtsch Pharm Ges. 1953;286(8):416-8. Undetermined Language. [Content Brief]
[2]. Pérez-Rebolledo A, et al. 4-nitroacetophenone-derived thiosemicarbazones and their copper(II) complexes with significant in vitro anti-trypanosomal activity. Eur J Med Chem. 2008 May;43(5):939-48. [Content Brief]
[3]. Alam A, et al. Novel Bis-Schiff's base derivatives of 4-nitroacetophenone as potent α-glucosidase agents: Design, synthesis and in silico approach. Bioorg Chem. 2022 Nov;128:106058. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.0551 mL | 30.2755 mL | 60.5510 mL | 151.3775 mL |
| 5 mM | 1.2110 mL | 6.0551 mL | 12.1102 mL | 30.2755 mL | |
| 10 mM | 0.6055 mL | 3.0276 mL | 6.0551 mL | 15.1378 mL | |
| 15 mM | 0.4037 mL | 2.0184 mL | 4.0367 mL | 10.0918 mL | |
| 20 mM | 0.3028 mL | 1.5138 mL | 3.0276 mL | 7.5689 mL | |
| 25 mM | 0.2422 mL | 1.2110 mL | 2.4220 mL | 6.0551 mL | |
| 30 mM | 0.2018 mL | 1.0092 mL | 2.0184 mL | 5.0459 mL | |
| 40 mM | 0.1514 mL | 0.7569 mL | 1.5138 mL | 3.7844 mL | |
| 50 mM | 0.1211 mL | 0.6055 mL | 1.2110 mL | 3.0276 mL | |
| 60 mM | 0.1009 mL | 0.5046 mL | 1.0092 mL | 2.5230 mL | |
| 80 mM | 0.0757 mL | 0.3784 mL | 0.7569 mL | 1.8922 mL | |
| 100 mM | 0.0606 mL | 0.3028 mL | 0.6055 mL | 1.5138 mL |