4-Nitropyrazole
Based on 1 Customer Validation
4-Nitropyrazole is a five-membered nitrogen-containing heterocyclic compound that can be used as a drug intermediate. 4-Nitropyrazole can be synthesized into antibiotics/antifungal/antiviral agents containing pyrazole rings. 4-Nitropyrazole is synthesized through C-H activation reactions to produce LRRK2 inhibitors, which are used in the research of Parkinson's disease.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.99%
- CAS 番号: 2075-46-9
- 分子式: C3H3N3O2
- 分子量:113.08
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 2075-46-9
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性状 Solid
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分子量 113.08
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分子式 C3H3N3O2
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Color White to off-white
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SMILES
O=[N+](C1=CNN=C1)[O-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 200 mg/mL (1768.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (614 KB)
- English - EN (614 KB)
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- Portuguese - PT (614 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Manfredini S,et al. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo[4,3-d]-1,2,3-triazin-4-one nucleosides. J Med Chem. 1992 Mar 6;35(5):917-24. [Content Brief]
[2]. Barron B, et al. A Concise Enantioselective Synthesis of Fluorinated Pyrazolo-Piperidine GSK3901383A Enabled by an Organocatalytic Aza-Michael Addition. Org Lett. 2024 Mar 1;26(8):1533-1538. [Content Brief]
[3]. Hrelia P, et al. Synthesis, metabolism and structure-mutagenicity relationships of novel 4-nitro-(imidazoles and pyrazoles) in Salmonella typhimurium. Mutat Res. 1998 Feb 2;397(2):293-301. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.8436 mL | 44.2180 mL | 88.4361 mL | 221.0902 mL |
| 5 mM | 1.7687 mL | 8.8436 mL | 17.6872 mL | 44.2180 mL | |
| 10 mM | 0.8844 mL | 4.4218 mL | 8.8436 mL | 22.1090 mL | |
| 15 mM | 0.5896 mL | 2.9479 mL | 5.8957 mL | 14.7393 mL | |
| 20 mM | 0.4422 mL | 2.2109 mL | 4.4218 mL | 11.0545 mL | |
| 25 mM | 0.3537 mL | 1.7687 mL | 3.5374 mL | 8.8436 mL | |
| 30 mM | 0.2948 mL | 1.4739 mL | 2.9479 mL | 7.3697 mL | |
| 40 mM | 0.2211 mL | 1.1055 mL | 2.2109 mL | 5.5273 mL | |
| 50 mM | 0.1769 mL | 0.8844 mL | 1.7687 mL | 4.4218 mL | |
| 60 mM | 0.1474 mL | 0.7370 mL | 1.4739 mL | 3.6848 mL | |
| 80 mM | 0.1105 mL | 0.5527 mL | 1.1055 mL | 2.7636 mL | |
| 100 mM | 0.0884 mL | 0.4422 mL | 0.8844 mL | 2.2109 mL |
4-Nitropyrazole 関連分類
HY-W002458 関連分類
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