F 16915
Based on 1 Customer Validation
F 16915, a Docosahexaenoic Acid (DHA, HY-B2167) derivative, is a potent pro-agent of DHA. F 16915 can prevent heart failure-induced atrial fibrillation.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.16%
- CAS 番号: 92510-91-3
- 分子式: C28H37NO2
- 分子量:419.60
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体内実験
F 16915 (1-5 g/day for 4 weeks) significantly reduces the infarct size and prevents the left ventricular free wall thinning[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague-Dawley rats (220-300 g) with heart failure induced by occlusion of left descending coronary artery and 2 months reperfusion[1]
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Dosage:100 mg/kg
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Administration:Daily oral gavage
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Result:Reduced the infarct size.
Prevented the left ventricular free wall thinning.
Reduced the de-phosphorylation of connexin43 from atria tissue.
化学情報
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CAS 番号 92510-91-3
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性状 Oil
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分子量 419.60
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分子式 C28H37NO2
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Color Colorless to light yellow
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SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(OCC1=CC=CN=C1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
体外:
DMSO : ≥ 100 mg/mL (238.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
純度とドキュメンテーション
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データシート (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3832 mL | 11.9161 mL | 23.8322 mL | 59.5806 mL |
| 5 mM | 0.4766 mL | 2.3832 mL | 4.7664 mL | 11.9161 mL | |
| 10 mM | 0.2383 mL | 1.1916 mL | 2.3832 mL | 5.9581 mL | |
| 15 mM | 0.1589 mL | 0.7944 mL | 1.5888 mL | 3.9720 mL | |
| 20 mM | 0.1192 mL | 0.5958 mL | 1.1916 mL | 2.9790 mL | |
| 25 mM | 0.0953 mL | 0.4766 mL | 0.9533 mL | 2.3832 mL | |
| 30 mM | 0.0794 mL | 0.3972 mL | 0.7944 mL | 1.9860 mL | |
| 40 mM | 0.0596 mL | 0.2979 mL | 0.5958 mL | 1.4895 mL | |
| 50 mM | 0.0477 mL | 0.2383 mL | 0.4766 mL | 1.1916 mL | |
| 60 mM | 0.0397 mL | 0.1986 mL | 0.3972 mL | 0.9930 mL | |
| 80 mM | 0.0298 mL | 0.1490 mL | 0.2979 mL | 0.7448 mL | |
| 100 mM | 0.0238 mL | 0.1192 mL | 0.2383 mL | 0.5958 mL |
F 16915 関連分類
HY-19886 関連分類
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