MethADP
Based on 1 Customer Validation
MethADP is a specific CD73 inhibitor.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.0%
- CAS 番号: 3768-14-7
- 分子式: C11H17N5O9P2
- 分子量:425.23
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
CD73[1].
MethADP (AMP-CP: 20 μM) causes a marked inhibition of adenosine formation (0.96±0.96 μM) compared to untreated controls (9.6±1.5 μM) in A498 and RT4 cells, and MethADP (100 μM) completely inhibits the adenosine formation[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 3768-14-7
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性状 Solid
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分子量 425.23
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分子式 C11H17N5O9P2
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Color White to off-white
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SMILES
O[C@@H]1[C@H](O)[C@@H](COP(O)(CP(O)(O)=O)=O)O[C@H]1N2C=NC3=C2N=CN=C3N
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別名
Adenosine 5'-(α,β-methylene)diphosphate; アデノシン 5′-(α,β-メチレン)二リン酸
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
H2O : 50 mg/mL (117.58 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.3517 mL | 11.7583 mL | 23.5167 mL | 58.7917 mL |
| 5 mM | 0.4703 mL | 2.3517 mL | 4.7033 mL | 11.7583 mL | |
| 10 mM | 0.2352 mL | 1.1758 mL | 2.3517 mL | 5.8792 mL | |
| 15 mM | 0.1568 mL | 0.7839 mL | 1.5678 mL | 3.9194 mL | |
| 20 mM | 0.1176 mL | 0.5879 mL | 1.1758 mL | 2.9396 mL | |
| 25 mM | 0.0941 mL | 0.4703 mL | 0.9407 mL | 2.3517 mL | |
| 30 mM | 0.0784 mL | 0.3919 mL | 0.7839 mL | 1.9597 mL | |
| 40 mM | 0.0588 mL | 0.2940 mL | 0.5879 mL | 1.4698 mL | |
| 50 mM | 0.0470 mL | 0.2352 mL | 0.4703 mL | 1.1758 mL | |
| 60 mM | 0.0392 mL | 0.1960 mL | 0.3919 mL | 0.9799 mL | |
| 80 mM | 0.0294 mL | 0.1470 mL | 0.2940 mL | 0.7349 mL | |
| 100 mM | 0.0235 mL | 0.1176 mL | 0.2352 mL | 0.5879 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
MethADP 関連分類
HY-112502 関連分類
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