製品番号: HY-B2050

トリフルラリン

(別名: Trifluralin)

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Based on 1 Customer Validation

Trifluralin is a selective, preemergence, soil-applied herbicide providing control of many important annual grass and broadleaf weed species. Trifluralin prevents weed growth by inhibiting root development through the interruption of mitosis. Trifluralin binds to tubulin and results in the failure of spindle apparatus and cell plate formation. Trifluralin inhibits radicle development on roots. Trifluralin inhibits cell mitosis. Trifluralin is considered to be neurotoxic and haematotoxic.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

純度: 98.0%
CAS 番号: 1582-09-8
分子式: C₁₃H₁₆F₃N₃O₄
分子量:335.28

保管条件:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year

Trifluralin 構造式

CAS 番号: 1582-09-8

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- Cellular Effect
- 体外実験
- 体内実験
化学情報
溶剤 & 溶解度
- 体外
純度とドキュメンテーション
参考文献
Help & FAQs
関連分類
Bioz

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-8	IC₅₀	750 nM Compound: 1	Antimicrobial activity against Cryptosporidium parvum infected in HCT8 cells assessed as parasite count after 72 to 120 hrs Antimicrobial activity against Cryptosporidium parvum infected in HCT8 cells assessed as parasite count after 72 to 120 hrs	[PMID: 21889338]
HFF	IC₅₀	0.52 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	1.8 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235V mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235V mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	1.9 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235L mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235L mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	13.8 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin V4L mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin V4L mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	2.8 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin S6I mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin S6I mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	23.3 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243S mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243S mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	23.4 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin T239I mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin T239I mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	27 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin L136F mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin L136F mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	4.1 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243C mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243C mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	4.2 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin F24H mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin F24H mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	5.1 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235T mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235T mutation infected in HFF cells by plaque assay	[PMID: 20145086]
HFF	IC₅₀	5.3 μM Compound: 13	Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin H28Q mutation infected in HFF cells by plaque assay Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin H28Q mutation infected in HFF cells by plaque assay	[PMID: 20145086]
THP-1	CC₅₀	>50 μM Compound: TFL	Cytotoxicity against human THP1 cells after 48 hrs by propidium iodide and SYBR14 satining-base flow cytometry Cytotoxicity against human THP1 cells after 48 hrs by propidium iodide and SYBR14 satining-base flow cytometry	[PMID: 19926293]
THP-1	IC₅₀	>50 μM Compound: TFL	Antileishmanial activity against Leishmania infantum A1 amastigotes infected in human THP1 cells assessed as reduction in intracellular parasite load after 48 hrs by Giemsa staining Antileishmanial activity against Leishmania infantum A1 amastigotes infected in human THP1 cells assessed as reduction in intracellular parasite load after 48 hrs by Giemsa staining	[PMID: 19926293]

体外実験

Trifluralin (Compound TFL) (22.3-1000 μg/mL) has cytotoxicity but no mutagenicity in Chinese hamster V79 cells and CHO-K1 cells^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

体内実験

Trifluralin (Compound TFL) (0-5000 mg/kg, in diet, 13 w) causes a reduction in absolute food consumption in parallel with a decrease in body weight gains in Wistar rats^[3].
Trifluralin (0-500 mg/kg, in diet, on day 6-15 of gestation) causes marked toxicity to the dams and the death of numerous conceptuses shortly after implantation or during the early embryonic stage of Wistar rats^[3].
Trifluralin (0-0.02 mg/L, 14 d) increases the AST in liver and blood serum, and ALP activity in the kidney of carp^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 1582-09-8
性状 Solid
分子量 335.28
分子式 C₁₃H₁₆F₃N₃O₄
Color Pink to red
SMILES

FC(C1=CC([N+]([O-])=O)=C(N(CCC)CCC)C([N+]([O-])=O)=C1)(F)F
別名

Trifluralin
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

溶剤 & 溶解度

体外:

DMSO : ≥ 100 mg/mL (298.26 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.9826 mL

14.9129 mL

29.8258 mL

5 mM

0.5965 mL

2.9826 mL

5.9652 mL

10 mM

0.2983 mL

1.4913 mL

2.9826 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (275 KB)
SDS (788 KB)
- English - EN (788 KB)
- Français - FR (788 KB)
- Deutsch - DE (788 KB)
- Norwegian - NO (788 KB)
- Español - ES (788 KB)
- Swedish - SV (788 KB)
- Italian - IT (788 KB)
- Korean - KR (788 KB)
- Portuguese - PT (788 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Grover, R., et al., (1997). Environmental fate of trifluralin. Reviews of environmental contamination and toxicology, 153, 1–64. [Content Brief]

[2]. C. Fernandes, et al., (2013). Characterization, Modes of Action and Effects of Trifluralin: A Review. InTech.

[3]. Ebert, E., et al., (1992). Toxicology and hazard potential of trifluralin. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 30(12), 1031–1044. [Content Brief]

[4]. Poleksić, V., & Karan, V. (1999). Effects of trifluralin on carp: biochemical and histological evaluation. Ecotoxicology and environmental safety, 43(2), 213–221. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.9826 mL	14.9129 mL	29.8258 mL	74.5645 mL
	5 mM	0.5965 mL	2.9826 mL	5.9652 mL	14.9129 mL
	10 mM	0.2983 mL	1.4913 mL	2.9826 mL	7.4565 mL
	15 mM	0.1988 mL	0.9942 mL	1.9884 mL	4.9710 mL
	20 mM	0.1491 mL	0.7456 mL	1.4913 mL	3.7282 mL
	25 mM	0.1193 mL	0.5965 mL	1.1930 mL	2.9826 mL
	30 mM	0.0994 mL	0.4971 mL	0.9942 mL	2.4855 mL
	40 mM	0.0746 mL	0.3728 mL	0.7456 mL	1.8641 mL
	50 mM	0.0597 mL	0.2983 mL	0.5965 mL	1.4913 mL
	60 mM	0.0497 mL	0.2485 mL	0.4971 mL	1.2427 mL
	80 mM	0.0373 mL	0.1864 mL	0.3728 mL	0.9321 mL
	100 mM	0.0298 mL	0.1491 mL	0.2983 mL	0.7456 mL

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トリフルラリン

Cell Cycle/DNA Damage Compound Library

Metabolism/Protease Compound Library

Anti-Aging Compound Library

Cytoskeleton Compound Library

Anti-Lung Cancer Compound Library

Human Metabolite Library

Mitochondrial Toxicity Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Pesticide Compound Library

High-Throughput Bioactive Compound Library

Environmental Pollutant Compound Library

生物活性

化学情報

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

トリフルラリン

Cell Cycle/DNA Damage Compound Library

Metabolism/Protease Compound Library

Anti-Aging Compound Library

Cytoskeleton Compound Library

Anti-Lung Cancer Compound Library

Human Metabolite Library

Mitochondrial Toxicity Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Pesticide Compound Library

High-Throughput Bioactive Compound Library

Environmental Pollutant Compound Library

生物活性

化学情報

溶剤 & 溶解度

純度とドキュメンテーション

参考文献

Help & FAQs

Complete Stock Solution Preparation Table

Trifluralin 関連分類

HY-B2050 関連分類