Abagovomab
Based on 1 publication(s) in Google Scholar
Abagovomab (Anti-Human CA-125 Recombinant Antibody) is a mouse monoclonal anti-idiotypic antibody that targets the tumor-associated antigen CA-125 (binding affinity: 0.5 nM). Produced by mouse hybridoma cells, Abagovomab mimics human TAA, CA-125. Abagovomab also induces humoral and cellular immune responses against ovarian cancer (oc).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: ≥95.0%
- CAS 番号: 792921-10-9
- 分子量:144.42 kDa
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
MedChemExpress(MCE)の使用を引用している文献 Abagovomab
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生物活性
Human IgG1 kappa
Human
MUC16
Abagovomab binds the paratope of the OC125 antibody with high affinity (0.5 nM) and functionally mimics the CA-125 antigen, as demonstrated by 93% inhibition of its OC125 binding by native CA-125[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-kappa
ELISA, FACS, Functional assay
化学情報
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CAS 番号 792921-10-9
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性状 Liquid
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分子量 144.42 kDa
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Color Colorless to light yellow
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SMILES
[Abagovomab]
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別名
Anti-Human CA-125 Recombinant Antibody
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輸送条件
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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J Am Chem Soc
A Spatially Controllable DNA Origami-Based T-Cell Cluster Engager for Precise Tumor Elimination. [Abstract]2026 Jan 21;148(2):2758-2768. PMID: 41504034
純度とドキュメンテーション
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データシート (257 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Inhibitory Antibodies User Guide (603 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
- Abagovomab
- 792921-10-9
- Anti-Human CA-125 Recombinant Antibody
- Transmembrane Glycoprotein
- ovarian cancer cells
- anti-anti-idiotypic antibodies
- non-MHC restricted cell-mediated cytotoxicity
- peritoneal carcinoma
- tumor-associated antigen CA-125
- ovarian cancer
- OC125 antibody
- fallopian tube cancer
- immune response inducer
- murine monoclonal anti-idiotypic antibody
- Inhibitor
- inhibitor
- inhibit