Activated EG3 Tail
Based on 1 Customer Validation
Activated EG3 Tail can be used in the synthesis of exon jumping oligomer conjugates.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.31%
- CAS 番号: 1380600-06-5
- 分子式: C43H47N3O10
- 分子量:765.85
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保管条件:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
生物活性
製品説明
体外実験
Activated EG3 Tail yields an oligomer conjugate that is complementary to the selected target site in the human dystrophin gene and can induce exon 51 skipping. Activated EG3 Tail can be applied to the research of muscular dystrophy[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1380600-06-5
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性状 Solid
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分子量 765.85
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分子式 C43H47N3O10
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Color White to off-white
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SMILES
O=C([C@]1([H])[C@]([C@@]2([H])C[C@]1([H])C=C2)([H])C3=O)N3OC(CCC(OCCOCCOCCOC(N(CC4)CCN4C(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (130.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3057 mL | 6.5287 mL | 13.0574 mL | 32.6435 mL |
| 5 mM | 0.2611 mL | 1.3057 mL | 2.6115 mL | 6.5287 mL | |
| 10 mM | 0.1306 mL | 0.6529 mL | 1.3057 mL | 3.2643 mL | |
| 15 mM | 0.0870 mL | 0.4352 mL | 0.8705 mL | 2.1762 mL | |
| 20 mM | 0.0653 mL | 0.3264 mL | 0.6529 mL | 1.6322 mL | |
| 25 mM | 0.0522 mL | 0.2611 mL | 0.5223 mL | 1.3057 mL | |
| 30 mM | 0.0435 mL | 0.2176 mL | 0.4352 mL | 1.0881 mL | |
| 40 mM | 0.0326 mL | 0.1632 mL | 0.3264 mL | 0.8161 mL | |
| 50 mM | 0.0261 mL | 0.1306 mL | 0.2611 mL | 0.6529 mL | |
| 60 mM | 0.0218 mL | 0.1088 mL | 0.2176 mL | 0.5441 mL | |
| 80 mM | 0.0163 mL | 0.0816 mL | 0.1632 mL | 0.4080 mL | |
| 100 mM | 0.0131 mL | 0.0653 mL | 0.1306 mL | 0.3264 mL |