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AF3485

AF3485 is a human mPGES-1 inhibitor that exhibits antitumor activity in vitro and in vivo. AF3485 inhibits tumor-associated angiogenesis by reducing PGE2 production, inhibiting EGFR signaling, and decreasing VEGF and FGF-2 expression. AF3485 reduced tumor growth in mice bearing human A431 xenograft tumors by subchronic administration.

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  • CAS 番号: 1195786-61-8
  • 分子式: C22H17F3N2O2
  • 分子量:398.38
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • AF3485 Chemical Structure
    AF3485 構造式
CAS 番号: 1195786-61-8
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    AF3485 Chemical Structure
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  • AF3485