Alagebrium bromide
Based on 6 publication(s) in Google Scholar
Alagebrium bromide is an analog of Alagebrium Chloride (HY-106024B), a glucose cross-link blocker. Alagebrium Chloride disrupts glucose cross-links and may improve ventricular and arterial compliance. Alagebrium Chloride improves left ventricular diastolic filling and has the potential to inhibit diastolic heart failure (DHF).
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- CAS 番号: 181069-80-7
- 分子式: C13H14BrNOS
- 分子量:312.23
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
MedChemExpress(MCE)の使用を引用している文献 Alagebrium bromide
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生物活性
化学情報
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CAS 番号 181069-80-7
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分子量 312.23
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分子式 C13H14BrNOS
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SMILES
O=C(C1=CC=CC=C1)C[N+]2=CSC(C)=C2C.[Br-]
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別名
ALT711 bromide
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (6)
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Journal Impact Factor
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Most Recent
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Biomaterials
Extracellular matrix glycation epigenetically regulates brain aging and neurodegeneration in the in vitro aged neurovascular model. [Abstract]2025 Jun 13:324:123504. PMID: 40543324 -
Free Radic Biol Med
APOE4 impairs Nrf2-PINK1/Parkin-dependent mitochondrial clearance through disrupted antioxidant and mitophagy signaling. [Abstract]2025 Nov 21:243:245-259. PMID: 41275935 -
Mol Med
D-mannose promotes diabetic wound healing through inhibiting advanced glycation end products formation in keratinocytes. [Abstract]2025 Jan 18;31(1):15. PMID: 39827347 -
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Am J Transl Res
Alagebrium targets the miR-27b/TSP-1 signaling pathway to rescue Nε-carboxymethyl-lysine-induced endothelial dysfunction. [Abstract]2019 Mar 15;11(3):1569-1580. PMID: 30972183
Alagebrium bromide purchased from MedChemExpress. Usage Cited in: Am J Transl Res. 2019 Mar 15;11(3):1569-1580. [Abstract]
Western blotting analysis of TSP-1 protein expression, and results show that TSP-1 expression in HUVECs treated with ALT-711 under CML-BSA condition is enhanced by miR-27b inhibitor.
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Cell Biomater
Diabetic hyperglycemia-induced glycation regulates tumor vasculature integrity via NF-κB-mediated GM-CSF secretion by tumor cells. [Abstract]2025 Aug 26:100186. PMID: 41058997
純度とドキュメンテーション
参考文献
Calculators
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