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United States

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製品番号: HY-122529

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Almurtide

Almurtide (nor-MDP), a muramyl dipeptide derivative with anti-inflammatory and anti-tumor activity. Almurtide also shows protective effects against intraperitoneal Pseudomonas aeruginosa infection or intravenously Candida albicans infection in mice. Almurtide also inhibits the carcinogenic Friend leukemia virus.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 61136-12-7
分子式: C₁₈H₃₀N₄O₁₁
分子量:478.45

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Almurtide 構造式

CAS 番号: 61136-12-7

容量

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体内実験

Almurtide (80 mg/kg; once daily for 4 consecutive days; via intraperitoneal, intravenous, or subcutaneous) stimulates macrophages nonspecifically and has anti-infective activity against Listeria monocytogenes. At the same time, it lacks oral activity and is synergistic with Gentamicin (HY-A0276A)^[2].
Almurtide (100 μg/mouse; s.c.; once for 2-3 months) prevents erythroleukemia in SJL/J mice caused by low-dose Friend leukemia virus and delays the occurrence of spontaneous breast tumors in RIII/Imr mice^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 61136-12-7
分子量 478.45
分子式 C₁₈H₃₀N₄O₁₁
SMILES

CC(N[C@@H](C=O)[C@H]([C@H](O)[C@H](O)CO)OCC(N[C@@H](C)C(N[C@@H](C(N)=O)CCC(O)=O)=O)=O)=O
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (268 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Díaz-Eufracio BI, et al. Exploring the chemical space of peptides for drug discovery: a focus on linear and cyclic penta-peptides. Mol Divers. 2018 May;22(2):259-267. [Content Brief]

[2]. Fraser-Smith E B, et al. Protective effect of muramyl dipeptide analogs against infections of Pseudomonas aeruginosa or Candida albicans in mice. Infection and immunity, 1981, 34(3): 676-683.

[3]. Acevedo H F, et al. Prevention of oncogenic viral infections in mice with CGP 11637, a synthetic muramyl dipeptide analog[J]. Antimicrobial agents and chemotherapy, 1985, 28(5): 589-596.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

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分子量分子量

希釈計算機

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体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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