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製品番号: HY-149890

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Anticancer agent 130

Anticancer agent 130 (compound 8d) is an anticancer agent that can significantly induce apoptosis in A549 cells.

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CAS 番号: 3038738-52-9
分子式: C₃₈H₄₆FN₅O₅
分子量:671.80

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Anticancer agent 130 構造式

CAS 番号: 3038738-52-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Anticancer agent 130 (compound 8d) is an anticancer agent that can significantly induce apoptosis in A549 cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	0.43 μM Compound: 8d	Anticancer activity against human A549 cells assessed as inhibition of cell proliferation by SRB assay Anticancer activity against human A549 cells assessed as inhibition of cell proliferation by SRB assay	[PMID: 37330115]
HeLa	IC₅₀	>30 μM Compound: 8d	Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation by SRB assay Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation by SRB assay	[PMID: 37330115]

化学情報

CAS 番号 3038738-52-9
分子量 671.80
分子式 C₃₈H₄₆FN₅O₅
SMILES

CCN(CC)C1=CC=C2C(OC(C(O)C3=CC=C(OCCN4CCN(C(CN5CCN(C(C6=CC=C(F)C=C6)=O)CC5)=O)CC4)C=C3)=C2)=C1
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (263 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Liu Y, et al. Anticancer evaluation of benzofuran derivatives linked to dipiperazine moiety. Bioorg Med Chem Lett. 2023 Jul 15;91:129378. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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