Anticancer agent 237
Anticancer agent 237 (compound 13) is a potent anticancer agent. Anticancer agent 237 shows cytotoxicity. Anticancer agent 237 induces apoptosis and cell cycle arrest at the S and G2/M phases.
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- CAS 番号: 17822-61-6
- 分子式: C18H24N2O3S
- 分子量:348.46
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Anticancer agent 237 (compound 13) (48 h) induces apoptosis and cell cycle arrest at the S and G2/M phases in HCT-116, MCF-7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HCT-116, MCF-7 cells
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Concentration:0-100 µM
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Incubation Time:48 h
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Result:Showed cytotoxicity with IC50s of 43.5, 62.4 µM for HCT-116, MCF-7 cells, respectively.
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Cell Line:HCT-116, MCF-7 cells
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Concentration:43.5 for HCT-116 cells, 62.4 for MCF-7 cells µM
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Incubation Time:48 h
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Result:Induced apoptosis with 2.24% of the population being in early apoptosis, 0.58% in late apoptosis, and 6.6% in the necrotic population in MCF-7 cells, led to 45.07% of the population being in early apoptosis, 0.42% in late apoptosis, and 0.02% necrotic population in HCT-116 cells.
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Cell Line:HCT-116, MCF-7 cells
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Concentration:0-100 µM
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Incubation Time:48 h
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Result:Induced cell cycle arrest at the S and G2/M phases.
化学情報
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CAS 番号 17822-61-6
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分子量 348.46
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分子式 C18H24N2O3S
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SMILES
O=S(C1=CC=C(C)C=C1)(NC(NC23CC4CC(C3)CC(C4)C2)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Anticancer agent 237 関連分類
HY-163808 関連分類
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