Anticancer agent 284
Anticancer agent 284 exhibits cytotoxicity against osteosarcoma cell line (Hos), non-small cell lung cancer cell line (A549), and colon cancer cell line (HCT-116). Anticancer agent 284 can impact the pRIPK3 kinase concentration in the A549 (2.97 pg/mL). Anticancer agent 284 can be used for the study of cancer.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C26H25N5O3S
- 分子量:487.57
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Anticancer agent 284 (Compound 4) cytotoxic against all the tested cell lines, with an IC50 activity order of HCT-116 (7.3 µM) > A549 (20.4 µM) > Hos (39.9 µM)[1].
Anticancer agent 284 slightly inhibis pRIPK3 in A549 cells (2.97 pg/mL)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:A549 human lung cancer cells
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Concentration:20.4 μM (treat with the IC50 concentration of the active compound)
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Incubation Time:24 h
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Result:Impacted the pRIPK3 kinase concentration in the A549 (2.97 pg/mL).
化学情報
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分子量 487.57
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分子式 C26H25N5O3S
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SMILES
CC1=CC=C(C=C1)S(=O)(N/N=C(C2=CC=C(C=C2)N/C=C3C(N(N=C/3C)C4=CC=CC=C4)=O)\C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)