Anticancer agent 46
Based on 1 Customer Validation
Anticancer agent 46 is an anti cancer agent. Anticancer agent 46 can be used in the research of gastric cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.73%
- CAS 番号: 2426686-17-9
- 分子式: C15H14ClN3OS
- 分子量:319.81
-
保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
生物活性
製品説明
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| GES1 | IC50 |
27.93 μM
Compound: 5n
|
Cytotoxicity against human GES-1 cells after 72 hrs by MTT assay
Cytotoxicity against human GES-1 cells after 72 hrs by MTT assay
|
[PMID: 30108734] |
| MCF7 | IC50 |
9.99 μM
Compound: 5n
|
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
|
[PMID: 30108734] |
| MGC-803 | IC50 |
>64 μM
Compound: 5n
|
Antiproliferative activity against human MGC803 cells after 24 hrs by MTT assay
Antiproliferative activity against human MGC803 cells after 24 hrs by MTT assay
|
[PMID: 30108734] |
| MGC-803 | IC50 |
0.93 μM
Compound: 5n
|
Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay
|
[PMID: 30108734] |
| MGC-803 | IC50 |
0.986 μM
Compound: 2
|
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
Antiproliferative activity against human MGC-803 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay
|
[PMID: 32438199] |
| MGC-803 | IC50 |
9.22 μM
Compound: 5n
|
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
|
[PMID: 30108734] |
| SMMC-7721 | IC50 |
19.18 μM
Compound: 5n
|
Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay
|
[PMID: 30108734] |
体外実験
Anticancer agent 46 (Compound 2) inhibits the proliferation of human gastric cancer MGC803 cells after 72 h, with an IC50 value of 0.986 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 2426686-17-9
-
性状 Solid
-
分子量 319.81
-
分子式 C15H14ClN3OS
-
Color Light yellow to yellow
-
SMILES
C/C(C1=CC(Cl)=CC=C1O)=N\NC(NC2=CC=CC=C2)=S
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 125 mg/mL (390.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (268 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1269 mL | 15.6343 mL | 31.2686 mL | 78.1714 mL |
| 5 mM | 0.6254 mL | 3.1269 mL | 6.2537 mL | 15.6343 mL | |
| 10 mM | 0.3127 mL | 1.5634 mL | 3.1269 mL | 7.8171 mL | |
| 15 mM | 0.2085 mL | 1.0423 mL | 2.0846 mL | 5.2114 mL | |
| 20 mM | 0.1563 mL | 0.7817 mL | 1.5634 mL | 3.9086 mL | |
| 25 mM | 0.1251 mL | 0.6254 mL | 1.2507 mL | 3.1269 mL | |
| 30 mM | 0.1042 mL | 0.5211 mL | 1.0423 mL | 2.6057 mL | |
| 40 mM | 0.0782 mL | 0.3909 mL | 0.7817 mL | 1.9543 mL | |
| 50 mM | 0.0625 mL | 0.3127 mL | 0.6254 mL | 1.5634 mL | |
| 60 mM | 0.0521 mL | 0.2606 mL | 0.5211 mL | 1.3029 mL | |
| 80 mM | 0.0391 mL | 0.1954 mL | 0.3909 mL | 0.9771 mL | |
| 100 mM | 0.0313 mL | 0.1563 mL | 0.3127 mL | 0.7817 mL |
Anticancer agent 46 関連分類
HY-146030 関連分類
Powered by Bioz