Anticancer agent 87
Anticancer agent 87 is a spirooxindole-furan derivative with anticancer activity. Anticancer agent 87 can be used for the research of breast adenocarcinoma and human liver cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C30H21BrCl2N2O3S
- 分子量:640.37
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Anticancer agent 87 (Compound 6f) potently inhibits the viability of MCF7 breast adenocarcinoma cells with an IC50 of 10.3 μM/mL[1].
Anticancer agent 87 potently inhibits the viability of HepG2 liver carcinoma cells with an IC50 of 3.5 μM/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
化学情報
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分子量 640.37
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分子式 C30H21BrCl2N2O3S
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SMILES
O=C1NC2=C(C=CC(Cl)=C2)[C@@]13N4CSCC4[C@@H](C5=CC=C(C6=CC=CC=C6Cl)O5)[C@@H]3C(C7=CC=C(Br)C=C7)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)