Anticancer agent 90
Anticancer agent 90 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity. Anticancer agent 90 has high inhibition against the two cell line from ovarian cancer (OVCAR-4), renal cancer (A498).
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- CAS 番号: 2977251-03-7
- 分子式: C33H32N2O10S3
- 分子量:712.81
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Anticancer agent 90 (compound 6d) (0.01 mM; 24 h) has low cytotoxicity, shows high inhibition against two cell lines, SK-MEL-5, OVCAR-4[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cell lines
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Concentration:0-200 μg/mL
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Incubation Time:24 hours
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Result:Showed nontoxic under the doses of 100 μg/mL against FRHK-4, Hep2, BGM, Vero, and Huh 7.5 cells, respectively.
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Cell Line:SK-MEL-5, OVCAR-4, and A498
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Concentration:0.01 mM
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Incubation Time:24 hours
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Result:Inhibited SK-MEL-5 and OVCAR-4 cell viability by 30.64% and 30.71%, respectively.
化学情報
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CAS 番号 2977251-03-7
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分子量 712.81
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分子式 C33H32N2O10S3
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SMILES
[H][C@]1([C@@H]([C@H]([C@@H](O[C@@H]1COC(C)=O)SC2=C(C(N)=C(S2)C(C3=CC=C(C=C3)C)=O)C4=NC5=C(S4)C=CC=C5)OC(C)=O)OC(C)=O)OC(C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)