Antimicrobial agent-50
Antimicrobial agent-50 is an anti-oomycete and Fungicidal agent. Antimicrobial agent-50 inhibits the activity of Mitochondrial respiratory chain complex III with an IC50 of 6.05 mg/L. Antimicrobial agent-50 inhibits ATP synthesis. Antimicrobial agent-50 exhibits protective activity against Phytophthora capsici in vivo. Antimicrobial agent-50 potently inhibits mycelial growth of Gaeumannomyces graminis, Rhizoctonia solani and Phytophthora capsici, with EC50 values of 2.97 mg/L, 1.86 mg/L and 0.74 mg/L, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 177776-73-7
- 分子式: C17H14O3
- 分子量:266.29
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
Antimicrobial agent-50 (Compound C2) (0.39-50.00 mg/L) potently inhibits mycelial growth of Gaeumannomyces graminis, Rhizoctonia solani and Phytophthora capsici, with EC50 values of 2.97 mg/L, 1.86 mg/L and 0.74 mg/L, respectively. At a concentration of 50.00 mg/L, this compound exhibits broad-spectrum in vitro fungicidal activity against another 6 tested phytopathogenic fungi/oomycetes[1].
Antimicrobial agent-50 causes severe ultrastructural damage to Phytophthora capsici hyphae, including cell wall thickening, mitochondrial degradation, and vacuole enlargement[1].
Antimicrobial agent-50 (12.50-50.00 mg/L) significantly inhibits the respiratory metabolism of Phytophthora capsici hyphae in a concentration-dependent manner, with an inhibition rate of 75.3% at 50.00 mg/L after 4 h of treatment[1].
Antimicrobial agent-50 (1-100 mg/L) inhibits the activity of mitochondrial respiratory chain complex III in Phytophthora capsici, with an IC50 of 6.05 mg/L, thereby causing a concentration-dependent decrease in intracellular ATP levels[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Animal Model:Adult worker honeybees[1]
-
Dosage:500 mg/L; 5000 mg/L; 50000 mg/L; >200 μg/bee
-
Administration:topical application to thorax; single dose
-
Result:Determined LD50 greater than 200 μg/bee.
Caused less than 10% mortality at dose greater than 200 μg/bee.
化学情報
-
CAS 番号 177776-73-7
-
分子量 266.29
-
分子式 C17H14O3
-
SMILES
O=C1OC(C2=CC=CC(OC3=CC=CC=C3)=C2)CC1=C
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
- Antimicrobial agent-50
- 177776-73-7
- Antimicrobial agent50
- Antimicrobial agent 50
- Fungal
- Mitochondrial Metabolism
- ATP Synthase
- adult worker honeybees
- Xanthomonas oryzae pv oryzae
- Pseudomonas syringae pv actinidiae
- Phytophthora capsici
- pepper seedlings
- mitochondrial respiratory chain
- Rhizoctonia solani
- ATP synthesis
- Gaeumannomyces graminis
- respiratory chain complex III
- Inhibitor
- inhibitor
- inhibit