BB-78485
BB-78485 is an LpxC metalloenzyme inhibitor with antibacterial activity. BB-78485 can inhibit LpxC with an IC50 value of 160 nM. BB-78485 can be used for the research of gram-negative selective antibacterials.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 207732-11-4
- 分子式: C23H20N2O4S
- 分子量:420.48
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
IC50: 160 nM(LpxC)[1]
BB-78485 can inhibit LpxC with an IC50 value of 160 nM[1].
BB-78485 has effect against D21 and D22 (lpxC101) with MICs values of 2 μg/mL and 0.016 μg/mL, respectively[1].
BB-78485 shows predominantly gram-negative activities against members of the Enterobacteriaceae, Serratia marcescens, Morganella morganii, Moraxella catarrhalis, Haemophilus influenzae, and Burkholderia cepacia with MICs values range from 1μg/mL to 32 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 207732-11-4
-
分子量 420.48
-
分子式 C23H20N2O4S
-
SMILES
O=C([C@@H](CC1=CC=C2C=CC=CC2=C1)NS(=O)(C3=CC=C4C=CC=CC4=C3)=O)NO
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)