BCM-599
BCM-599 is a HBV (hepatitis B virus) capsid assembly inhibitor with the activity of inhibiting HBV capsid assembly. BCM-599 showed an IC50 value of 0.88μM and a CC50 value of 144μM in HepG2.2.15 cells. When used in combination with lamivudine, BCM-599 showed a synergistic inhibitory effect on viral concentration. BCM-599 can be used as an effective combined inhibition option for HBV infection.
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- CAS 番号: 1820763-99-2
- 分子式: C14H10Cl2FN3O2
- 分子量:342.15
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 2.2.15 | CC50 |
144 μM
Compound: 36; BCM-599
|
Cytotoxicity against human HepG2(2.2.15) cells after 24 hrs by MTS assay
Cytotoxicity against human HepG2(2.2.15) cells after 24 hrs by MTS assay
|
[PMID: 28383274] |
化学情報
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CAS 番号 1820763-99-2
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分子量 342.15
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分子式 C14H10Cl2FN3O2
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SMILES
FC1=CC=C(C=C1)C(NCC(NC2=C(N=C(C=C2)Cl)Cl)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)